Choriocarcinomatous differentiation in rectal adenocarcinoma: A rare occurrence

Abstract

Letters to Editor non-availability of medical staff. In one of the study, it was indicated that 143 public facilities found absenteeism of 45% doctors from PHCs with 56% of time found to be closed with an unpredictable pattern of closure and absenteeism during regular hour visit. [2] A survey report from Madhya Pradesh in 2007 states that out of 24,807 qualified doctors and 94,026 qualified paramedical staff mapped in the survey in the state, 18,757 (75.6%) and 67,793 (72.1%) were working in the private sector respectively highlighting the government failure to provide basic infrastructure to doctors and other health care workers in rural areas. [7] This could be tackle by focusing on skill up gradation, capacity development and capability reinvigoration and limiting the scope for practice of illicit and unqualified practitioners. Thus, primary health care in India needs to be re-evaluate and immediately warrants reforms and concrete steps to be taken, otherwise this tug of war between growth and human resource development remains will continue forever.

Primary Rectal Tumor With Extensive Choriocarcinoma Differentiation in a Woman With Lung, Liver and Disseminated Peritoneal Disease: A Primary Rectal Adenocarcinoma With Extensive Choriocarcinoma Differentiation or Primary Rectal Choriocarcinoma?

“…[1][2][3][4][5][6][7][8][9][10][11][12][18][19][20][21][22][23][24][25] In adenocarcinomas of the gastrointestinal tract, choriocarcinomatous differentiation can manifest in different forms. [1][2][3][4][5][6][7][8][9][10][11][12][16][17][18][19][20][21][22][23][24][25] This can range from isolated β-HCG-positive malignant syncytiotrophoblastic giant cells in poorly differentiated adenocarcinomas, through mixed tumors, to pure choriocarcinoma. [1][2][3][4][5][6][7][8][9]...…”

“…[1][2][3][4][5][6][7][8][9][10][11][12][16][17][18][19][20][21][22][23][24][25] This can range from isolated β-HCG-positive malignant syncytiotrophoblastic giant cells in poorly differentiated adenocarcinomas, through mixed tumors, to pure choriocarcinoma. [1][2][3][4][5][6][7][8][9][10][11][12][16][17][18][19][20][21][22][23][24][25] Previous publications have proposed that most choriocarcinomas arise through the dedifferentiation process from a prior carcinoma or adenocarcinoma. [6][7][8][9][10][11]…”

Primary Adenocarcinoma with Focal Choriocarcinomatous Differentiation in the Sigmoid Colon

“…16 Only 20 cases of colorectal choriocarcinoma (including the case described here) have been reported worldwide (Table 1). [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] In the literature, primary colorectal choriocarcinoma was associated with adenocarcinoma in all except four cases, 6,12,15,17 in which only choriocarcinoma was noted and was accompanied by metastatic tumors at the time of diagnosis in 16 of 20 cases (80%). The median survival period was eight months (range, 0.5-60 months).…”

“…Primary colorectal choriocarcinoma is an even rarer tumor; only 16 cases have been published in the English medical literature, and only three cases have been reported in Korea. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Most of these tumors were associated with adenocarcinoma. We report a case involving a 61-year-old woman diagnosed with primary adenocarcinoma with focal choriocarcinomatous differentiation in the sigmoid colon.…”

A rare case of primary rectal choriocarcinoma and review of the literature

“…[1][2][3][4][5] Primary choriocarcinoma of colon is extremely rare, and only 18 cases have been previously published in medical literature based on English. [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] These tumors usually have poor prognosis and are associated with adenocarcinoma. We present a case of primary rectal choriocarcinoma with a good response to systemic chemotherapy including bleomycin, etoposide and cisplatin (BEP protocol) and review the literature on this rare tumor.…”