Choroid plexus carcinoma in an adolescent male: a case report

Abstract

Introduction/background Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children. Case presentation We report the case of an adolescent male belonging to central India who had presented with a history of persistent headache, projectile vomiting, neck stiffness, and an episode of generalized tonic-clonic seizure. Neurological examination was suggestive of a space-occupying lesion. Further neuroimaging was suggestive of a large left-sided choroid plexus carcinoma, later confirmed on pathological examination. Gross total resection was achieved and followed by radiation therapy. His recovery was satisfactory without any major events despite suffering from such a malignancy with a poor prognosis. Conclusion In the absence of a global consensus on choroid plexus carcinoma management, our patient underwent a successful gross total resection and received postoperative radiotherapy. He made a satisfactory recovery with a further plan to review with gadolinium-enhanced neuroimaging at a later date. We conclude that, when possible, achieving gross total resection is of utmost importance.

Durability of an endoscopic management strategy for recurrent choroid plexus carcinoma with a comprehensive molecular characterization: illustrative case

“…Over time, increased size, vascularity, mutagenicity, and dissemination of untreated CPC impact treatment strategy and may ultimately make GTR more difficult or impossible to achieve. 15,[18][19][20] Although several previous reports have detailed endoscopic resection for intraventricular choroid plexus papilloma, [21][22][23] the role of upfront endoscopic resection of CPC has been limited historically, given the hemorrhagic nature and voluminous size of the tumor. Advantages of endoscopy for intraventricular tumor removal relate to the minimally invasive nature of the approach, including the potential for shorter length of stay, reduced morbidity, and control of blood loss, which is often a limiting factor in CPC resection.…”

Management and outcome of Scrotal Abscess

“…Therefore, if a scrotal tumor, sepsis, or intestinal obstruction are present along with an acute scrotum, a preoperative CT scan should be recommended. [23][24][25][26][27][28][29][30][31][32][33][34][35][36]…”

Choroid plexus carcinoma: A case report

“…Patients who have undergone GTR have significantly better survival rates than those patients who have undergone subtotal resection. 9 Adjuvant chemotherapy can be used after surgery which causes shrinkage of tumour tissue but experience with this modality is limited. Irradiation following surgery is associated with improved survival but this modality is avoided in young children.…”