Choroid plexus papilloma of the third ventricle: angiography, preoperative embolization, and histology

M, H; Marx, William F.; Khanam, Humaira; Jensen, Mary E.

doi:10.1007/s002340000470

Cited by 37 publications

(31 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the catheterization of narrow arteries in infants is not always feasible, 7) as only 6 of 13 procedures were successful. 3,6,7,9) In the present case, the efficacy of the embolization was unclear because only one of the feeding arteries from the anterior choroidal artery was embolized. However, the second surgery was safely carried out without excessive bleeding.…”

Section: Discussionmentioning

confidence: 72%

Efficacy of Multi-staged Surgery and Adjuvant Chemotherapy for Successful Treatment of Atypical Choroid Plexus Papilloma in an Infant -Case Report-

Takahashi

Yamamoto

Aoyama

et al. 2009

Neurol. Med. Chir.(Tokyo)

View full text Add to dashboard Cite

A 12-month-old girl presented with a rare atypical choroid plexus papilloma manifesting as conscious disturbance and vomiting. Magnetic resonance (MR) imaging revealed a well-delineated 5 × 6-cm lobulate mass in the right lateral ventricle. Only partial removal of the tumor was performed because of excessive intraoperative hemorrhage at the first surgery. The histological diagnosis was atypical choroid plexus papilloma. To control the intraoperative hemorrhage, embolization of the feeding artery was performed before the second surgery, and the tumor was macroscopically totally removed. MR imaging disclosed a small residual tumor which showed relatively rapid growth. The patient underwent the third removal 5 months after the second surgery. Two months later, MR imaging showed a cystic lesion with a small nodule adjacent to the midbrain, indicating dissemination of the tumor. The lesion was successfully treated with chemotherapy. Atypical choroid plexus papilloma was recently defined in the classification of the World Health Organization, so clinical data based on these criteria are lacking to establish the therapeutic strategy. Total resection of atypical choroid plexus papilloma is the most reliable treatment at present. However, postoperative chemotherapy should be considered for recurrence or dissemination.

show abstract

Section: Discussionmentioning

confidence: 72%

Efficacy of Multi-staged Surgery and Adjuvant Chemotherapy for Successful Treatment of Atypical Choroid Plexus Papilloma in an Infant -Case Report-

Takahashi

Yamamoto

Aoyama

et al. 2009

Neurol. Med. Chir.(Tokyo)

View full text Add to dashboard Cite

show abstract

“…As the third ventricle is small and complex in its anatomy, it presents certain difficulties for surgical tumor removal. 4 Moreover, given the anatomical features of the third ventricle, the clinical presentation of tumors localized there occurs earlier than for tumors inside the lateral ventricles. 25 Among children with such lesions, one of the most common features is the development of hypertensive hydrocephalus.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic monoportal removal of a choroid plexus papilloma in the posterior third ventricle in a child

Sufianov¹,

Gaibov²,

Sufianov³

2015

PED

View full text Add to dashboard Cite

Currently, only a few reports describe the minimally invasive removal of choroid plexus papillomas (CPPs) and, to the best of the authors' knowledge, no reports detail the resection of such a papilloma through an endoscopic approach in infants. The authors here describe the endoscopic removal of a third ventricle CPP in a child. A 5-month-old male infant presented with progressive macrocephaly, vomiting, and convulsions. A lesion in the posterior third ventricle was detected on brain MRI. Because of the patient's very young age, neuroendoscopy was used as the least invasive technique. The tumor was completely resected through a monoportal neuroendoscopic approach. Histologically, the tumor was classified as a WHO Grade I CPP. After surgery, the patient's condition improved, with no complications during his recovery. Ten-month follow-up neuroimaging revealed no evidence of tumor recurrence or progressive hydrocephaly. In view of the successful neuroendoscopic excision of this posterior third ventricle CPP, the authors believe that this method seems promising in the treatment of young children with intraventricular lesions.

show abstract

“…15,20,27 Gross-total resection has been associated with excellent prognosis, 9,18,20 with 5-year survival being close to 100% after complete resection, but survival is only 56% after subtotal resection. 6,14,15,17,[19][20][21]24,27 Complete initial removal of the tumor is essential to prevent further tumor growth or recurrence, malignant degeneration, 5 continued overproduction of CSF and hydrocephalus, the need for adjuvant therapies such as radiotherapy or chemotherapy, or the morbidity of repeat surgery. …”

Section: Discussionmentioning

confidence: 99%

“…12 In response to this difficulty, endovascular embolization has been advocated as a means to reduce intraoperative blood loss for these tumors. 6,19,20 It has also been suggested that less intraoperative bleeding due to embolization leads to a higher rate of complete resection and better outcome. 11 However, many series have reported a low rate of successful embolization when attempted due to small tortuous vessels that are difficult or impossible to cannulate, or feeding arteries that are judged to also perfuse deep brain structures.…”

Section: B C Kennedy Et Almentioning

confidence: 99%

Superior parietal lobule approach for choroid plexus papillomas without preoperative embolization in very young children

Kennedy¹,

Cloney²,

Anderson

et al. 2015

PED

View full text Add to dashboard Cite

OBJECT Choroid plexus papillomas (CPPs) are rare neoplasms, often found in the atrium of the lateral ventricle of infants, and cause overproduction hydrocephalus. The extensive vascularity and medially located blood supply of these tumors, coupled with the young age of the patients, can make prevention of blood loss challenging. Preoperative embolization has been advocated to reduce blood loss and prevent the need for transfusion, but this mandates radiation exposure and the additional risks of vessel injury and stroke. For these reasons, the authors present their experience using the superior parietal lobule approach to CPPs of the atrium without adjunct therapy. METHODS A retrospective review was conducted of all children who presented to Columbia University/Morgan Stanley Children's Hospital of New York with a CPP in the atrium of the lateral ventricle and who underwent surgery using a superior parietal lobule approach without preoperative embolization. RESULTS Nine children were included, with a median age of 7 months. There were no perioperative complications or new neurological deficits. All patients had intraoperative blood loss of less than 100 ml, with a mean minimum hematocrit of 26.9% (range 19.6%–36.2%). No patients required a blood transfusion. The median follow-up was 39 months, during which time no patient demonstrated residual or recurrent tumor on MRI, nor did any have an increase in ventricular size or require CSF diversion. CONCLUSIONS The superior parietal lobule approach is safe and effective for very young children with CPPs in the atrium of the lateral ventricle. The results suggest that preoperative embolization is not essential to avoid transfusion or achieve overall good outcomes in these patients. This management strategy avoids radiation exposure and the additional risks associated with embolization.

show abstract

Choroid plexus papilloma of the third ventricle: angiography, preoperative embolization, and histology

Cited by 37 publications

References 0 publications

Efficacy of Multi-staged Surgery and Adjuvant Chemotherapy for Successful Treatment of Atypical Choroid Plexus Papilloma in an Infant -Case Report-

Efficacy of Multi-staged Surgery and Adjuvant Chemotherapy for Successful Treatment of Atypical Choroid Plexus Papilloma in an Infant -Case Report-

Endoscopic monoportal removal of a choroid plexus papilloma in the posterior third ventricle in a child

Superior parietal lobule approach for choroid plexus papillomas without preoperative embolization in very young children

Contact Info

Product

Resources

About