Choroidal neovascularisation secondary to serpiginous choroiditis: The value of OCT-angiography in diagnosis and response to therapy with aflibercept

Polo, R. Campos; Sánchez, C. Rubio; Trancón, Angel Sánchez

doi:10.1016/j.oftale.2018.12.012

Cited by 1 publication

(3 citation statements)

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“…It is known that among the prevalent theories regarding the pathogenesis of CNV is inflammatory-induced angiogenesis mediated by vascular endothelial growth factor (VEGF). 6 , 12 , 15 It is no surprise then, that the anti-VEGF medications exert a beneficial impact on CNV. Furthermore, damage to the RPE and Bruch’s membrane complex caused by chronic inflammation enables these new capillaries to pass from the choroid to the sub-RPE and subretinal space.…”

Section: Discussionmentioning

confidence: 99%

“…Campos Polo et al 6 used OCTA for the detection of CNV and its response to anti-VEGF injections in SC. Aggarwal et al 10 reported that OCTA is a helpful diagnostic tool for the detection of type 1 CNV in patients with tuberculous serpiginious-like choroiditis TB-SLC when conventional multimodal imaging methods fail to assist in the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…As a result, OCTA contributes significantly to the identification and monitoring of chorioretinopathies and their related complications such as CNV. 5 , 6 , 7 , 8 , 9 , 10 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Serpiginous Choroiditis Complicated with Choroidal Neovascular Membrane Detected using Optical Coherence Tomography Angiography: A Case Series and Literature Review

Perente¹,

Kotsiliti²,

Taliantzis³

et al. 2021

tjo

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Serpiginous choroiditis (SC) is a rare, chronic, recurrent, progressive disease of unknown origin. The inflammatory process of SC can disrupt Bruch’s membrane, allowing occasional choroidal vascular growth, leading to significant visual loss even in the healed stages of the disease. Optical coherence tomography angiography (OCTA) can help in the detection of choroidal neovascular membrane (CNV), leading to a definitive diagnosis and thereby guide the initiation of intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment. We report herein two cases of SC complicated with a CNV detected with OCTA and treated with a series of anti-VEGF injections.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%