Choroidal Thickness in Childhood Obesity

Buluş, Ayşe Derya; Can, Mehmet Erol; Baytaroğlu, Ata; Çan, Gamze; Çakmak, Hasan Basri; Andıran, Nesibe

doi:10.3928/23258160-20161219-02

Cited by 31 publications

(35 citation statements)

References 41 publications

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“…Previous studies have shown that the choroidal thickness is higher in patients with BMI between 18-24 compared to those with BMI < 18.5 (384 ± 102 μm versus 378 ± 86 μm; p<0.01) [18]. Similarly, studies in obese women and children have shown that choroidal thickness is higher in patients with obesity compared to healthy control population [30,31]. In our study, we also observed higher choroidal thickness values in participants with obesity compared to healthy controls (Table 3), though it did not reach statistical significance.…”

Section: Plos Onementioning

confidence: 87%

Effect of weight loss on the retinochoroidal structural alterations among patients with exogenous obesity

et al. 2020

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Section: Plos Onementioning

confidence: 87%

Effect of weight loss on the retinochoroidal structural alterations among patients with exogenous obesity

et al. 2020

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“…This chronic inflammation also has the potential to produce changes in the retina and macular layer (20). Indeed, previous MetS: metabolic syndrome studies have shown that obesity reduces the thickness of the retinal nerve fiber layer in children and affects choroid tissue (21,22,23). Some studies have shown that obesity leads to changes in the macular layers in children.…”

Section: Discussionmentioning

confidence: 99%

Macular Variability in Children and Adolescents with Metabolic Syndrome: A Cross-sectional Study Examining the Associations with Anthropometric Measurements, Metabolic Parameters and Inflammatory Markers

Öztürk¹,

Özen²,

Çatlı³

et al. 2020

Jcrpe

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Macular damage may be observed in obesity and metabolic syndrome (MetS), a condition which leads to chronic subclinical inflammation and affects most organ systems. To investigate the association between macular variability and anthropometric measurements, metabolic parameters, and inflammatory markers in children and adolescents with MetS. Methods: Two hundred and twenty eyes of 62 obese and 48 healthy children and adolescents were examined. Bilateral macular retinal thickness (MRT) and macular retinal volume (MRV) were measured in all subjects using optical coherence tomography. Associations between mean MRT and mean MRV and age, auxological measurements including body mass index standard deviation scores (BMI-SDS) and waist circumference-SDS (WC-SDS), metabolic parameters and inflammatory parameters including neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio and systemic immune-inflammatory index (SIII) were investigated. Results: No statistically significant difference was observed between the groups in terms of age or sex distribution (p>0.05). Mean MRT (r=-0.326, p=0.007) and MRV (r=-0.303, p=0.007) values in the obese group with MetS decreased as homeostasis model assessmentinsulin resistance (HOMA-IR) values increased. SIII values were higher in obese groups, but particularly in obese subject with MetS, compared to the control group (p=0.021). The decrease in mean MRT (r=-0.544, p=0.046) and MRV (r=-0.651, p=0.031) in the obese subjects with MetS was negatively correlated with NLR. Mean MRT and MRV decreased in all obese subjects as SIII increased (p<0.05). Conclusion: This is the first study to show that mean MRT and MRV values decrease as BMI-SDS, WC-SDS and HOMA-IR increase in obese children and adolescents with MetS. NLR and SIII may serve as markers of chronic inflammation in obese children with MetS associated with macular damage.

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“…Koroid kalınlık değişimine neden olan çok sayıda metabolik hastalık vardır. Egzersiz, gebelik, erkek cinsiyet, sildenafil kullanımı, prediyabetik retinopati, çocukluk çağı obesitesinin koroid kalınlığını artırdığı bildirilmiştir (12)(13)(14)(15)(16)(17) . Konjestif kalp yetersizliği, karotis stenozu, sigara, kahve, ileri yaş, çocuklarda demir eksikliği anemisi, diyabetik makülar ödem ve proliferatif diyabetik retinopatinin eşlik ettiği diyabetin koroid kalınlığını azalttığı bildirilmiştir (7,(18)(19)(20)(21)(22) .…”

Section: Discussionunclassified

Effect of diastolic heart dysfunction due to hypertrophic cardiomyopathy on choroidal thickness

Bayramoğlu¹,

Özbay²,

Sayın³

2018

İKSST

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Choroidal Thickness in Childhood Obesity

Abstract: CT increases in childhood obesity. Findings revealed that adiposity causes a significant increase in CT, and it may be related to ocular complications. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:10-17.].

Cited by 31 publications

References 41 publications

Effect of weight loss on the retinochoroidal structural alterations among patients with exogenous obesity

Effect of weight loss on the retinochoroidal structural alterations among patients with exogenous obesity

Macular Variability in Children and Adolescents with Metabolic Syndrome: A Cross-sectional Study Examining the Associations with Anthropometric Measurements, Metabolic Parameters and Inflammatory Markers

Effect of diastolic heart dysfunction due to hypertrophic cardiomyopathy on choroidal thickness

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