Chromatographic behaviour of 4′-dimethylaminoazobenzene-4-sulphonyl derivatives of amines in liquid—solid systems

Synthesis and application of 4-dipropylaminodiazabenzene-4′-isothiocyanate to the derivatization and chromatographic separation of biogenic amines

“…One means of facilitating their analysis is through derivatization. Among the many reagents developed for these amines are the following: phenylisothiocyanate (PITC) [5], the chloride of 4-dimethylaminodiazaPresented at Balaton Symposium on High Performance Separation Methods, Sidfok, Hungary, September 1 3, 1999 benzene-4'-sulphonic acid (DABS-C1) [6,7], and dimethylaminodiaza-benzene-4'-isothiocyanate (DA-BITC) [8]. The derivatives obtained are compounds of lower polarity and larger molecular size, which decreases their adsorption on an active carrier surface, thereby increasing the selectivity of the chromatographic separation and the detection sensitivity [9][10][11][12].…”