Chromatographic separation for domoic acid using a fragment imprinted polymer

Molecular imprinted polymers as synthetic receptors for the analysis of myco- and phyco-toxins

“…As previously seen for microcystin LR, the fragmental imprinting approach has been used by Kubo et al to develop an imprinted polymer for DA 54 . Several commercial cyclic dicarboxylic compounds related to phthalic acid were tested to mimic molecular sub-structures of DA.…”

Synthesis and characterization of metal ion imprinted nano-porous polymer for the selective recognition of copper

“…Recent reviews reveal the current status of MIPs as alternatives to antibodies in sorbent assays (Lavignac et al, 2004), MIPs and their use in biomimetic sensors (Haupt and Mosbach, 2000), MIPs as new molecular recognition materials for selective solidphase extraction of organic compounds (Esteban, 2001), MIPs for drug delivery (Lorenzo and Concheiro, 2004), separation and screening of compounds of biological origin using MIPs (Xu et al, 2004). Moreover, MIPs are also finding application in many fields such as MIP membranes for the improved recognition of biomolecules in aqueous medium (Silvestri et al, 2006), for the recognition of proteins (Bossi et al, 2007), in the chromatographic separation of domoic acid using a fragment imprinted polymer (Kubo et al, 2006) and also in novel biphasic separations utilizing highly selective MIPs as biorecognition solvent extraction agents (Castell et al, 2006). Europium(III) containing imprinted polymers prepared by RAFT polymerization was utilized for luminescent sensing of organophosphates (Southard et al, 2007) and concentration dependent atrazine-atrazine complex formation that in turn promotes the selectivity in atrazine-imprinted polymers (Lavignac et al, 2006) are available in the literature.…”

Molecularly Imprinted Adsorbents for Selective Separation and/or Concentration of Environmental Pollutants

“…Therefore, we suppose that fragment imprinting is applicable for flexible compounds by the optimization of the arrangement of the functional monomer, which can interact with the functional groups of the targeting compounds. 38,40 Fragment imprinting has expanded the possibility of the MIP technique for a number of targeting compounds including toxins, rare natural compounds, and flexible compounds. However, in general, these results shown above as well as reports by other papers treated relatively hydrophobic compounds as the targeting compounds.…”

“…32 In the former technique, we employed a fragment template as a part of the structure of the targeting molecule, and achieved selective separation and/or concentration of endocrine disrupters and natural toxins. [33][34][35][36][37][38][39][40][41][42] In the latter technique, we utilized selective recognition based on the interval of the ionic functional groups in the targeting molecule, and achieved selective concentration of water-soluble pollutants as well as selective photodegradation of toxins. [43][44][45][46][47][48][49] In this review, we present the fundamental concepts of both techniques and their applications for environmental analyses, a photocatalysis, and a stimulus response hydrogel.…”