La Cabaña peridotite is part of a dismembered ophiolite complex located within the metamorphic basement of the Coastal Cordillera of south-central Chile, and is the only location in Chile were Cr-spinels have been described so far. The La Cabaña peridotite is part of the Western Series unit, which comprises meta-sedimentary rocks, metabasites, and serpentinized ultramafic rocks. This unit has been affected by greenschist-facies metamorphism with reported peak PT conditions of 7.0-9.3 kbar and 380°-420°C. Within La Cabaña peridotite Cr-spinels are present in two localities: Lavanderos and Centinela Bajo. In Lavanderos, Cr-spinel occurs in small chromitite pods and as accessory/disseminated grains with a porous or spongy texture in serpentinite, whereas in Centinela Bajo Cr-spinel is present as accessory zoned grains in partly serpentinized dunites, and in chromitite blocks. All Cr-spinels display variable degrees of alteration to Fe 2+ -rich chromite with a variation trend of major elements from chromite to Fe 2+ -rich chromite similar to those observed in other locations, i.e., an increase in Fe 2 O 3 and FeO, a decrease in Al 2 O 3 and MgO. Cr 2 O 3 content increases from chromite to Fe 2+ -rich chromite in chromitite pods from Lavanderos and chromitite blocks from Centinela Bajo, but decreases in ferrian chromite zones in accessory grains from Centinela Bajo. The minor element (Ti, V, Zn, Ni) content is mostly low and does not exceed 0.4 wt.%, with the exception of MnO (<0.9 wt.%), which shows a correspondence with increasing degree of alteration. Cr# (Cr/Cr+ Al) versus Mg# (Mg/Mg+Fe 2+ ) and Fe 3+ /Fe 3+ +Fe 2+ versus Mg# plots are used to illustrate the Cr-spinel alteration process. Overall, the Cr-spinels from Lavanderos (chromitite pods and disseminated grains) exhibit Cr# values ranging from 0.6 to 1.0, Mg# (Mg/Mg+Fe 2+ ) below 0.5, and (Fe 3+ /Fe 3+ +Fe 2+ ) <0.4. Cr-spinels from chromitites in Centinela Bajo have Cr# and Mg# values that range from 0.65 to 1.0, and 0.7-0.3, respectively, and (Fe 3+ /Fe 3+ +Fe 2+ )<0.4. Accessory Cr-spinels from Centinela Bajo have Cr# and Mg# values that range from 0.55 to 1.0, and 0.6-<0.1, respectively. The (Fe 3+ /Fe 3+ +Fe 2+ ) ratio is less than 0.4 in chromite cores and Fe 2+ -rich chromite, and >0.5 in ferrian chromite and Cr-magnetite. Interpretation of the data obtained and Cr-spinel textures indicate that the alteration of Cr-spinel is a progressive process that involves in its initial stages the reaction of chromite with olivine under watersaturated conditions to produce clinochlore and Fe 2+ -rich chromite. During this stage the chromite can also incorporate Ni, Mn, and/or Zn from the serpentinization fluids. As alteration progresses, Fe 2+ -rich chromite loses mass resulting in the development of a spongy texture. In a later stage and under more oxidizing conditions Fe 3+ is incorporated in chromite/Fe 2+ -rich chromite shifting its composition to an Fe 3+ -rich chromite (i.e., ferrian chromite). Depending on the fluid/rock and Cr-spinel/ silicate ratios, Cr-...