Chromobacterium violaceum endocarditis and hepatic abscesses treated successfully with meropenem and ciprofloxacin

Lim, Ivan; Stride, Peter; Horvath, Robert; Hamilton-Craig, C.; Chau, Phi P

doi:10.5694/j.1326-5377.2009.tb02454.x

Cited by 14 publications

(8 citation statements)

References 11 publications

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“…The association of Chromobacterium violaceum infection with CGD has been previously described, mainly in children since the hereditary nature of the disease and almost none in adults with skin and soft tissue infections [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. Nonetheless, this association does not seem to be directly related to an increase in mortality [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Chromobacterium violaceum Periareolar Infection, First Non-Lethal Case in Colombia: Case Report and Literature Review

Díaz

Martin

Ortiz

et al. 2021

Infectious Disease Reports

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Chromobacterium violaceum is a facultative anaerobic, Gram-negative rod found in different ecosystems, especially tropical and subtropical areas. Human infections are rare, and just a few cases have been reported in literature. In this paper, we present the first non-lethal infection due to Chromobacterium violaceum, in an adult male with polycystic kidney disease in Colombia. Periareolar soft tissue infection was documented with isolation of Chromobacterium violaceum. Clinical manifestations, treatment, and outcome are shown.

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Section: Discussionmentioning

confidence: 99%

Chromobacterium violaceum Periareolar Infection, First Non-Lethal Case in Colombia: Case Report and Literature Review

Díaz

Martin

Ortiz

et al. 2021

Infectious Disease Reports

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“…Infection often occurs via a traumatic injury or by drinking contaminated water, and cellulitis or an abscess may or may not form at the site 1 . Systemic clinical symptoms are sepsis and visceral abscesses in the liver, lung, spleen and kidneys 2,3 .…”

Section: Introductionmentioning

confidence: 99%

Liver abscesses by Chromobacterium violaceum: a case report of a rare disease

Orsetti¹,

Markiewicz²,

Epstein³

et al. 2013

OA Case Reports

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IntroductionChromobacterium violaceum is a Gram-negative bacillus often found in soil and water of tropical and subtropical regions. Human infection by this bacterium is rare; however, when it occurs, it is associated with high mortality rates if not diagnosed or treated correctly or early enough. Systemic clinical symptoms include sepsis and visceral abscesses in the liver. The combination of percutaneous drainage of abscesses and systemic antibiotic therapy remains the most common treatment. Currently, it is believed that diagnosis via computed tomography scan and ultrasound-guided aspiration must be done before beginning antibiotic therapy. This report discusses liver abscesses by Chromobacterium violaceum. Case reportWe report a case of C. violaceum infection in Brazil in a patient who had rapid evolution of signs and multiple liver abscesses. Treatment consisted of interventional radiology and ciprofloxacin without the need for surgical intervention. ConclusionLiver abscesses caused by C. violaceum can cause high mortality rates if not treated correctly. Early diagn-osis will allow less painful drainage and antibiotics will help manage this infection effectively.

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“…The opportunistic pathogens Pseudomonas aeruginosa and Chromobacterium violaceum are involved in human and animal morbid and mortal antibioticresistant infections (Sirinavin et al, 2005;Lim et al, 2009;Strateva and Yordanov, 2009). Pseudomonas aeruginosa is one of the leading nosocomial pathogens worldwide (Strateva and Yordanov, 2009), infecting patients suffering from cystic fibrosis, AIDS, chronic granulomatous diseases, burns, ventilator-associated pneumonia, renal transplantations, and aplastic anemia as well as patients recovering from heart surgery.…”

Section: Introductionmentioning

confidence: 99%

Blocking of Pseudomonas aeruginosa and Chromobacterium violaceum lectins by diverse mammalian milks

Zinger-Yosovich

Iluz

Sudakevitz

et al. 2010

Journal of Dairy Science

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Pseudomonas aeruginosa and Chromobacterium violaceum morbid and mortal infections are initiated by bacterial adherence to host-cell receptors via their adhesins, including lectins (which also contribute to bacterial biofilm formation). Pseudomonas aeruginosa produces a galactophilic lectin, PA-IL (LecA), and a fucophilic (Lewis-specific) lectin, PA-IIL (LecB), and C. violaceum produces a fucophilic (H-specific) lectin, CV-IIL. The antibiotic resistance of these bacteria prompted the search for glycosylated receptor-mimicking compounds that would function as glycodecoys for blocking lectin attachment to human cell receptors. Lectins PA-IL and PA-IIL have been shown to be useful for such glycodecoy probing, clearly differentiating between human and cow milks. This article describes their usage, together with CV-IIL and the plant lectin concanavalin A, for comparing the anti-lectin-dependent adhesion potential of diverse mammalian milks. The results show that the diverse milks differ in blocking (hemagglutination inhibition) and differential binding (Western blots) of these lectins. Human milk most strongly inhibited the 3 bacterial lectins (with PA-IIL superiority), followed by alpaca, giraffe, and monkey milks, whereas cow milk was a weak inhibitor. Lectin PA-IL was inhibited strongly by human, followed by alpaca, mare, giraffe, buffalo, and monkey milks, weakly by camel milk, and not at all by rabbit milk. Lectins PA-IIL and CV-IIL were also most sensitive to human milk, followed by alpaca, monkey, giraffe, rabbit, and camel milks but negligibly sensitive to buffalo and mare milks. Plant lectin concanavalinA, which was used as the reference, differed from them in that it was much less sensitive to human milk and was equally as sensitive to cow milk. These results have provided important information on the anti-lectin-dependent adhesion potential of the diverse milks examined. They showed that human followed by alpaca, giraffe, and Rhesus monkey milks efficiently blocked the binding of both the galactophilic and fucophilic (>mannophilic) pathogen lectins. The results also proved the advantage of isolated pathogenic bacterial lectins as superb probes for unveiling bacterial adhesion-blocking glycodecoys. The chosen milks or their polymeric glycans might be implicated in blocking lectin-dependent adhesion of antibiotic-resistant pathogens leading to skin, eye, ear, and gastrointestinal infections.

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Chromobacterium violaceum endocarditis and hepatic abscesses treated successfully with meropenem and ciprofloxacin

Cited by 14 publications

References 11 publications

Chromobacterium violaceum Periareolar Infection, First Non-Lethal Case in Colombia: Case Report and Literature Review

Chromobacterium violaceum Periareolar Infection, First Non-Lethal Case in Colombia: Case Report and Literature Review

Liver abscesses by Chromobacterium violaceum: a case report of a rare disease

Blocking of Pseudomonas aeruginosa and Chromobacterium violaceum lectins by diverse mammalian milks

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