Chromoblastomycosis in Texas

Wilson, Sidney J.; Hulsey, Sim; Weidman, Fred D.

doi:10.1001/archderm.1933.01450040110010

Cited by 27 publications

(6 citation statements)

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“…The second case of CBM in the United States was not described until 1933 in Texas; this patient presented with ulcerated and nodular lesions on the right foot (96). Over subsequent decades, scattered cases have been described, particularly from Texas and Louisiana (84,(100)(101)(102)(103)(104)(105)(106)(107).…”

Section: Chromoblastomycosis In the Americasmentioning

confidence: 99%

Chromoblastomycosis

et al. 2017

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SUMMARY Chromoblastomycosis (CBM), also known as chromomycosis, is one of the most prevalent implantation fungal infections, being the most common of the gamut of mycoses caused by melanized or brown-pigmented fungi. CBM is mainly a tropical or subtropical disease that may affect individuals with certain risk factors around the world. The following characteristics are associated with this disease: (i) traumatic inoculation by implantation from an environmental source, leading to an initial cutaneous lesion at the inoculation site; (ii) chronic and progressive cutaneous and subcutaneous tissular involvement associated with fibrotic and granulomatous reactions associated with microabscesses and often with tissue proliferation; (iii) a nonprotective T helper type 2 (Th2) immune response with ineffective humoral involvement; and (iv) the presence of muriform (sclerotic) cells embedded in the affected tissue. CBM lesions are clinically polymorphic and are commonly misdiagnosed as various other infectious and noninfectious diseases. In its more severe clinical forms, CBM may cause an incapacity for labor due to fibrotic sequelae and also due to a series of clinical complications, and if not recognized at an early stage, this disease can be refractory to antifungal therapy.

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Section: Chromoblastomycosis In the Americasmentioning

confidence: 99%

Chromoblastomycosis

et al. 2017

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“…14 The second case in the United States was reported by Wilson et al in 1933. 15 In 1935, as the name “chromoblastomycosis” suggested that the etiological agents display budding yeasts in the tissue, Moore and Almeida (1935) proposed the term “chromomycosis” to replace “chromoblastomycosis”. 16 More cases were reported in European countries.…”

Section: Historymentioning

confidence: 99%

Chromoblastomycosis: an etiological, epidemiological, clinical, diagnostic, and treatment update

Brito

Bittencourt

2018

An. Bras. Dermatol.

102

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Chromoblastomycosis is a chronic, granulomatous, suppurative mycosis of the skin and subcutaneous tissue caused by traumatic inoculation of dematiaceous fungi of the family Herpotrichiellaceae. The species Fonsecaea pedrosoi and Cladophialophora carrionii are prevalent in regions where the disease is endemic. Chromoblastomycosis lesions are polymorphous: verrucous, nodular, tumoral, plaque-like, and atrophic. It is an occupational disease that predominates in tropical and subtropical regions, but there have been several reports of cases in temperate regions. The disease mainly affects current or former farm workers, mostly males, and often leaving disabling sequelae. This mycosis is still a therapeutic challenge due to frequent recurrence of lesions. Patients with extensive lesions require a combination of pharmacological and physical therapies. The article provides an update of epidemiological, clinical, diagnostic, and therapeutic features.

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“…In addition to fungi with rounded shapes colored dark brown, septated, and with no budding, with different morphology from Blastomyces sp, differentiating chromoblastomycosis from blastomycosis. The researchers also pointed out that there was no involvement of internal organs (Wilson et al, 1933).…”

Section: Histopathologymentioning

confidence: 99%

“…They described the formation of conidia chains and the phialides aspect of the fungus, identified as Phialophora verrucosa, as well as in the case of Boston, reported in 1915 by Medlar and Lane. The authors noted that the characteristics of micromorphology were different from Brazilian patients' culture, whose agent at the time was called Acrotheca pedrosoi (Wilson et al, 1933).…”

Section: Culturementioning

confidence: 99%

Diagnosis of chromoblastomycosis: an historical review

Borges

Eda

Ianhez³

et al. 2022

Rev Patol Trop

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Chromoblastomycosis is a skin infection caused by dematiaceous fungi, characterized by a verrucous plaque on the limbs. It mainly affects rural workers in tropical countries. The purpose of this review is to identify how the diagnostic methods used in the propaedeutic of chromoblastomycosis emerged and were developed. The MeSH terms “chromoblastomycosis” or “chromomycosis” or “verrucous dermatitis” and “diagnosis” were used to search articles indexed in MEDLINE and LILACS databases. The description of a first-time-used method in diagnosing chromoblastomycosis or modifications and innovations in an existing technique was the criteria used to deem the article eligible. The first methods described in diagnosing chromoblastomycosis were histopathological examination and culture, which characterizes and defines the disease in the early 20th century. Subsequently, they were described as direct microscopic examination, fine needle aspiration for cytology, electron microscopy, serology, molecular tests, scintigraphy, nuclear magnetic resonance and dermoscopy. Tests based on the direct identification of the fungus through biopsy, culture, or direct microscopy are the oldest and more employed methods for diagnosing chromoblastomycosis. The polymerase chain reaction was introduced in the last few decades and is a promising technique. Dermoscopy of chromoblastomycosis shows blackish red dots and white and pink areas along with scaling. Other techniques, such as serology and skin testing for delayed-type hypersensitivity, have not been incorporated into clinical practice. KEY WORDS: Chromoblastomycosis; diagnosis; review.

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Chromoblastomycosis in Texas

Cited by 27 publications

References 1 publication

Chromoblastomycosis

Chromoblastomycosis

Chromoblastomycosis: an etiological, epidemiological, clinical, diagnostic, and treatment update

Diagnosis of chromoblastomycosis: an historical review

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