Chromoendoscopy in small bowel capsule endoscopy: Blue mode or Fuji Intelligent Colour Enhancement?

Blue mode does not offer any benefit over white light when calculating Lewis score in small-bowel capsule endoscopy

“…With the current study we demonstrated that the use of BM, despite our initial hypothesis [7] , offered little aid (in comparison to WL) in LS calculation. In fact, LS calculation with BM showed slighly weaker (as compared to LS-WL) correlation to FC (rho = 0.472 vs rho = 0.490), although this did not reach statistical significance (P = 0.938).…”

“…Calprotectin, on the other hand, is a protein complex of the S-100 family of calcium binding proteins [7] . It is found in high concentration in the cytosol of neutrophils and is resistant to intestinal degradation for up to a week, thus distributed throughout the stool where it can be readily detected using standard enzyme linked immunosorbent assays (ELISA) [8] .…”

“…The experience with BM application in SBCE reading is even more limited [7,1,22] . BM is a colour coefficient shift of light in the short wavelength range (490-430 nm) superimposed onto a WL image.…”

“…They prospectively reviewed a total of 20 SBCE from patients with cirrhosis, at speed of 8 fps, and identified more erosions than with WL. We recently showed that BM provides image improvement for many SBCE lesion categories, but is more useful in enhancing visualisation of surface mucosal changes, e.g., mucosal breaks, ulcerations (in > 90% of cases) and mucosal cobblestoning [7] . This seems to be of particular importance in LS calculation, as one of the three LS parameters is the presence and number of mucosal breaks/ulcers.…”

“…Virtual chromoendoscopy has been already widely used in conventional endoscopy, aiming to improve diagnostic yield by enhancing the contrast between background and surface mucosal abnormalities, through narrowing the bandwidth of WL to that of blue-green light. To date, the published experience of its use in SBCE is only limited [7,[18][19][20][21] . Furthermore, the ability of chromoendscopy to improve detection rate of clinically significant lesions during SBCE is still questionable [21] .…”