Chromogenic and fluorogenic “off–on–off” chemosensor for selective and sensitive detection of aluminum (Al³⁺) and bifluoride (HF₂⁻) ions in solution and in living Hep G2 cells: synthesis, experimental and theoretical studies

Abstract

<p>A simple pyridine-dicarbohydrazide based colorimetric and fluorometric chemosensor L was designed and synthesized for Al3+ ions sensing in organo aqueous solution. In presence of Al3+ ions, probe L exhibited visible...</p>

1,8‐Naphthalimide‐Based Chemosensors: A Promising Strategy for Detection of Metal Ions in Environmental and Biological Systems

“…[130][131][132][133][134][135][136][137] This non-essential metal ion is found to have a determinant effect on biological and environmental systems. [138][139][140][141][142][143][144][145] Studies have found that the excess presence of Al 3 + leads to various neurological disorders like dementia, Alzheimer's disease, and Parkinson's disease. [146][147][148][149][150] Whereas, its high concentration in soil has a detrimental effect on plant growth and affects its productivity.…”

“…The third‐most prevalent metal ion on the planet, aluminium has several uses in daily life in various forms like cosmetics, food supplements, water purifiers, and pharmaceutics [130–137] . This non‐essential metal ion is found to have a determinant effect on biological and environmental systems [138–145] . Studies have found that the excess presence of Al 3+ leads to various neurological disorders like dementia, Alzheimer's disease, and Parkinson's disease [146–150] .…”

A naphthalene-based azo armed molecular framework for selective sensing of Al3+

“…1 Although there are many analytical techniques for detecting ions, their operation demands skilled operators, high equipment costs, and complex preparatory processes. [2][3][4][5][6] A transition metal is an integral part of an enzyme that regulates biological activity, yet it can be detrimental to the environment and human life; thus, it is a real paradox of the environment. 7 Aluminium, when absorbed in our body from various sources such as aluminium-based utensils and medicines, circulates to almost all tissue, reaches plasma through iron-binding protein, and is stored in the brain.…”