Chromogenic Chemodosimeter for Highly Selective Detection of Cyanide in Water and Blood Plasma Based on Si–O Cleavage in the Micellar System

Abstract

A novel silylated imine was designed to act efficiently in a chemodosimeter approach for the selective detection of cyanide in an aqueous micellar CTABr solution. This simple system allows the detection of cyanide, with high sensitivity and specific selectivity, in water and in human blood plasma.

Aggregation-Induced Emission-Based Material for Selective and Sensitive Recognition of Cyanide Anions in Solution and Biological Assays

“…Cyanide anions inhibit the mitochondrial electron transport in respiratory chain via binding with a ferric form of cytochrome P450 . The cyanide anions are the most toxic and cause serious damage to human health such as affecting the central nervous system and living environment. − Cyanide is extensively utilized in industrial factories particularly in gold mining, synthetic fiber, herbicides, and electroplating technology, and the presence of cyanide in environment and drinking water can cause a variety of diseases. − Furthermore, cyanide salts have been employed in the preparation of organic compounds and polymers, for example, nylon, nitrile rubber, acrylo nitrile-based polymer and acrylic plastics . These human activities in the modern industry releases cyanide anions in the environment which ultimately enters the human body via drinking water and the food chain. ,, The World Health Organization (WHO) stipulates the permissible limit of cyanide anions in water to about 1.9 μM .…”

Quantifying cyanide in water and foodstuff using corrin-based CyanoKit technologies and a smartphone

“…11 To avoid such situations in the future, more appropriate point-of-need tests are required that can accurately and rapidly identify foodstuff at risk. 12,13 Herein, we report on a smartphone-based device for the quantitative detection of biological endogenous cyanide (CN − ) in water and foodstuff using CyanoKit technologies (Cyanoguard AG, Wädenswil, CH). Thus far, CyanoKit technology has been constrained to the semi-quantitative detection of cyanide by the "naked-eye" using a colour reference chart.…”

Highly sensitive detection of low-level water content in organic solvents and cyanide in aqueous media using novel solvatochromic AIEE fluorophores

“…32,33 To date, reports relating sensors that recognized cyanide in complete water have been scarce. [34][35][36][37][38][39] We believe that there is large room for improvement in terms of sensitivity and applicability, and that it thereby is important to develop effective chemosensors for detection of cyanide in aqueous media.…”