2024
DOI: 10.1080/22221751.2024.2339942
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Chromosomal integration and plasmid fusion occurring in ST20 carbapenem-resistant Klebsiella pneumoniae isolates coharboring bla NDM-1 and bla IMP-4 induce resistance transmission and fitness variation

Qiucheng Shi,
Huangdu Hu,
Qian Yu
et al.

Abstract: To investigate the epidemiology of ST20 carbapenem-resistant Klebsiella pneumoniae (CRKP) in China, and further explore the genomic characteristics of bla IMP-4 and bla NDM-1 coharboring isolates and plasmid contributions to resistance and fitness. Seven ST20 CRKP isolates were collected nationwide, and antimicrobial susceptibility testing was performed. Antimicrobial resistance genes, virulence genes, and plasmid re… Show more

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