Chronic Auricular Fibrillation

McMillan, Robert L.

doi:10.1001/jama.1947.02890170010003

Cited by 18 publications

(4 citation statements)

References 9 publications

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“…The first 50 patients reported in the present series were shown to have dysrhythmias that were resistant to drugs, yet 86 per cent of these were successfully converted to sinus rhythm by direct-current shock. Gold (1950) considered that quinidine should no longer be used, but McMillan and Welfare (1947) thought that an attempt to convert chronic atrial fibrillation 80%5 to sinus rhythm, using quinidine, should be made in all patients. Relatively few toxic reactions to quinidine were reported by Sokolow (1951), but Rokseth and Storstein (1963) reported loss of consciousness, and collapse requiring resuscitation, in up to 6 per cent of patients being treated with quinidine for the conversion of dysrhythmias.…”

Section: Discussionmentioning

confidence: 99%

Appraisal of electroconversion in treatment of cardiac dysrhythmias.

Resnekov¹,

McDonald²

1968

Heart

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and his colleagues (Lown, Amarasingham, and Neuman, 1962a;Lown et al., 1962b) described the experimental development and successful clinical use of direct-current shock for the conversion of atrial and ventricular dysrhythmias to sinus rhythm, which was soon confirmed by others (O'Brien, Resnekov, and McDonald, 1964;Oram et al., 1964;Morris et al., 1964). An analysis of the indications, results, and complications of the method is presented below; this is based on observations that have been made on 220 consecutive patients with atrial and ventricular dysrhythmias which were associated with a wide variety of underlying heart disease, and treated by direct-current shock. METHODSClinical and Laboratory. A careful history was taken from all patients before treatment, with particular note of the duration of the dysrhythmias, drug therapy, and past cardiac surgery. Patients were examined clinically before direct-current shock and on the day after it. Twelve-lead standard electrocardiograms were recorded, and if the nature of the dysrhythmia was still uncertain the effect of carotid sinus compression was noted, or additional leads, such as lead CR1 or an oesophageal lead, were recorded. Three chest radiographs were taken before and after treatment: a postero-anterior view, a lateral view (right), and a penetrated antero-posterior grid view at 122 cm. (40 in.) to indicate the size of the left atrium. The electrocardiogram and chest radiographs were repeated on the day after treatment, and sometimes on the second day after treatment if there had been a significant alteration in heart size after directcurrent shock. -The over-all size of the heart was estimated by the cardiothoracic ratio (Danzer, 1919), and the left atrium was graded from the penetrated antero-posterior grid view into normal (N), slight (+ 1),

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Section: Discussionmentioning

confidence: 99%

Appraisal of electroconversion in treatment of cardiac dysrhythmias.

Resnekov¹,

McDonald²

1968

Heart

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“…Quinidine, one of the oldest antiarrhythmic drugs, was used extensively in the 20th century for a variety of arrhythmias, including AF ( Askey, 1946 ; McMillan and Welfare, 1947 ; Wegria, 1947 ). The combination of quinidine and verapamil has similar efficacy in preventing AF recurrences as sotalol but with better safety profile ( Fetsch et al, 2004 ; Patten et al, 2004 ).…”

Section: Early Antiarrhythmic Drugs For Rhythm Controlmentioning

confidence: 99%

“…However, concerning the two primary endpoints of improved survival and improved quality of life, catheter ablation has not yet proven superior to antiarrhythmic drug therapy as demonstrated by the Catheter Ablation vs. Antiarrhythmic Drug Therapy for AF randomized clinical trial (CABANA; n = 2,204 patients; 5-years follow up) ( Moreno and Zamorano, 2014 ; Packer et al, 2018 ). In addition, AF catheter ablation faces its own host of considerable limitations, such as higher costs, limited availabilities of skilled electrophysiologists and experienced centers, procedural risks, and patients’ ablation candidacy, to name just a few.…”

Section: Evolving Therapeutic Strategiesmentioning

confidence: 99%

Revisiting Antiarrhythmic Drug Therapy for Atrial Fibrillation: Reviewing Lessons Learned and Redefining Therapeutic Paradigms

2020

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“…The age of the patient, the aetiology of the heart disease, the presence of cardiac failure or cardiomegaly, and the duration of the arrhythmia have all been considered (Viko et al, 1923;Wolff and White, 1929;Harris, 1929;McMillan and Welfare, 1947;Holzman and Brown, 1951;Sokolow and Ball, 1956).…”

mentioning

confidence: 99%

Quinidine Therapy after Mitral Valvotomy

Aber¹

1962

Thorax

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Chronic Auricular Fibrillation

Cited by 18 publications

References 9 publications

Appraisal of electroconversion in treatment of cardiac dysrhythmias.

Appraisal of electroconversion in treatment of cardiac dysrhythmias.

Revisiting Antiarrhythmic Drug Therapy for Atrial Fibrillation: Reviewing Lessons Learned and Redefining Therapeutic Paradigms

Quinidine Therapy after Mitral Valvotomy

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