Chronic Cadmium Intoxication and Renal Injury Among Workers of a Small-scale Silver Soldering Company

Choi, Won-Jun; Kang, Shan; Ham, Seunghon; Chung, Wookyung; Kim, Ae Jin; Kang, Myunghee

doi:10.1016/j.shaw.2020.03.005

Cited by 7 publications

(8 citation statements)

References 26 publications

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“…Although the present article is focused on environmental exposure to Cd, one should not ignore that another source of intoxication with this element is the inhalation of airborne Cd particles in the workplace (e.g., in the production of alloys and batteries; the coating, enameling, and smelting of metals; and the printing of textiles) [87][88][89][90][91][92][93][94]. The concentration of Cd in the blood and urine of individuals occupationally exposed to this element exceeds the "normal concentration" of this heavy metal by many times, and is higher than that noted in persons who are not occupationally exposed, reaching 34 µg/L in the blood and 62 µg/g creatinine in the urine [90].…”

Section: The Current CD Exposure Level In Industrialized Countriesmentioning

confidence: 99%

“…The very limited data from the last 10 years show that the mean concentration of this heavy metal in this organ is 16.0 ± 13.2 µg/g w.w. in subjects aged 37.1 ± 18.7 [112]. The concentration of Cd in the kidneys of individuals occupationally exposed to this xenobiotic [2,[88][89][90]94] may be many times higher (150-395 µg/g w.w.) than in the general population (Table 4). Cd accumulates in the body mainly in the form of complexes with MT.…”

Section: Kidneys As the Main Organ Of CD Accumulation In The Bodymentioning

confidence: 99%

“…Since acute poisoning with this toxic element is very rare nowadays, the risk of acute kidney damage is negligible on a global scale. Chronic occupational [90,93,94] and environmental [7,16,40,126,127] exposure to Cd may cause or contribute to kidney injury; however, the risk of damage to this organ in the general population at the low and moderately low exposure levels that currently occur in many developed and developing countries has not been fully estimated.…”

Section: As a Nephrotoxic Factormentioning

confidence: 99%

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Current Levels of Environmental Exposure to Cadmium in Industrialized Countries as a Risk Factor for Kidney Damage in the General Population: A Comprehensive Review of Available Data

Smereczański

Brzóska

2023

IJMS

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The growing number of reports indicating unfavorable outcomes for human health upon environmental exposure to cadmium (Cd) have focused attention on the threat to the general population posed by this heavy metal. The kidney is a target organ during chronic Cd intoxication. The aim of this article was to critically review the available literature on the impact of the current levels of environmental exposure to this xenobiotic in industrialized countries on the kidney, and to evaluate the associated risk of organ damage, including chronic kidney disease (CKD). Based on a comprehensive review of the available data, we recognized that the observed adverse effect levels (NOAELs) of Cd concentration in the blood and urine for clinically relevant kidney damage (glomerular dysfunction) are 0.18 μg/L and 0.27 μg/g creatinine, respectively, whereas the lowest observed adverse effect levels (LOAELs) are >0.18 μg/L and >0.27 μg/g creatinine, respectively, which are within the lower range of concentrations noted in inhabitants of industrialized countries. In conclusion, the current levels of environmental exposure to Cd may increase the risk of clinically relevant kidney damage, resulting in, or at least contributing to, the development of CKD.

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Section: The Current CD Exposure Level In Industrialized Countriesmentioning

confidence: 99%

Section: Kidneys As the Main Organ Of CD Accumulation In The Bodymentioning

confidence: 99%

Section: As a Nephrotoxic Factormentioning

confidence: 99%

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Current Levels of Environmental Exposure to Cadmium in Industrialized Countries as a Risk Factor for Kidney Damage in the General Population: A Comprehensive Review of Available Data

Smereczański

Brzóska

2023

IJMS

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“…It is dangerous to all living organisms, including plants and animals [5,6]. When plants experiences toxic Cd, food chains are also probably affected by it, which may further lead to several human health problems such as renal failure, osteoporosis, liver cirrhosis, and Itai-Itai diseases [7][8][9][10][11]. It inhibits growth; activates or inhibits enzymes; affects water balance and ion transport; interferes with chlorophyll biosynthesis; inhibits various enzymes involved in the Calvin cycle; disrupts the evolution of O 2 over photosystem II (PSII); affects the transfer of electrons between PSI and PSII; and inhibits the activity of a variety of enzymes including carbonic anhydrase, NADP + glyceraldehyde-3-phosphate dehydrogenase, phosphoenolpyruvate carboxylase, ribulose-1,5-bisphosphate carboxylase oxygenase, fructose bis-phosphatase, and fructose-6phosphate kinase [12,13].…”

Section: Introductionmentioning

confidence: 99%

Cadmium-Tolerant Plant Growth-Promoting Bacteria Curtobacterium oceanosedimentum Improves Growth Attributes and Strengthens Antioxidant System in Chili (Capsicum frutescens)

Patel

Al-Keridis

et al. 2022

Sustainability

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The remediation of potentially toxic element-polluted soils can be accomplished through the use of microbial and plant-assisted bioremediation. A total of 32 bacteria were isolated from soil samples contaminated with potentially toxic elements. The isolated bacterial strain DG-20 showed high tolerance to cadmium (up to 18 mM) and also showed bioaccumulative Cd removal properties, as demonstrated by atomic absorption spectroscopy studies. By sequencing the 16S rRNA gene, this strain was identified as Curtobacterium oceanosedimentum. Under stress and normal conditions, isolate DG-20 also produced a wide range of plant growth promoting traits, including ammonia production (51–73 µg/mL) and IAA production (116–183 µg/mL), alongside siderophore production and phosphate solubilization. Additionally, pot experiments were conducted to determine whether the strain could promote Chili growth when Cd salts are present. Over the control, bacterial colonization increased root and shoot lengths significantly up to 58% and 60%, respectively. Following inoculation with the Cd-tolerant strain, the plants also increased in both fresh and dry weight. In both the control and inoculated plants, Cd was accumulated more in roots than in shoots, indicating that Chili was phytostabilizing Cd levels. Besides improving the plant attributes, Cd-tolerant bacteria were also found to increase the amount of total chlorophyll, proline, total phenol, and ascorbic acid in the soil when added to the soil. These results suggest that the inoculant provides protection to plants from negative effects. The results of the present study predict that the combined properties of the tested strain in terms of Cd tolerance and plant growth promotion can be exploited for the purpose of the bioremediation of Cd, and for the improvement of Chili cultivation in soils contaminated with Cd.

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“…In 2014, the European Union stated the tolerable cadmium intake per week in 2.5 µg kg −1 of body weight [35]. Cadmium intoxication may lead to renal tubular injury [36], hepatic, skeletal and cardiovascular damage, and even cancer [37]. Humans can be daily exposed to Cd via air, drinking water, or food.…”

Section: Introductionmentioning

confidence: 99%

Sensing Cd(II) Using a Disposable Optical Sensor Based on a Schiff Base Immobilisation on a Polymer-Inclusion Membrane. Applications in Water and Art Paint Samples

et al. 2021

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A disposable colour-changeable optical sensor based on an interesting polymer inclusion-membrane (PIM) was designed to determine Cd(II) ions in aqueous medium. The Schiff base 2-acetylpyridine benzoylhydrazone (2-APBH) immobilised on the polymer membrane was used as a sensing molecule. The amounts of the PIM components were optimised by a 32 fractional factorial design with two central points and two blocks. The best optical sensor composition consisted of 2.5 g of poly(vinylchloride) (PVC) as a base polymer, 3 mL of tributyl phosphate (TBP) as a plasticiser, and 0.02 g of 2-APBH as a reagent. The sensor showed a good linear response in the range from 0.02 mg L−1 (limit of detection) to 1 mg L−1 of Cd(II) under the following experimental conditions: pH 9.5 (adjusted using ammonium chloride buffer solution at 0.337 mol L−1), 60 min of exposure time plus 2 min of sonication (pulses at 2 s intervals), and 10 min of short-term stability. The relative standard deviation of the method was determined to be 4.04% for 0.4 mg L−1 of Cd(II). The optical sensor was successfully applied to the determination of Cd(II) in natural-water and art-paint samples.

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Chronic Cadmium Intoxication and Renal Injury Among Workers of a Small-scale Silver Soldering Company

Cited by 7 publications

References 26 publications

Current Levels of Environmental Exposure to Cadmium in Industrialized Countries as a Risk Factor for Kidney Damage in the General Population: A Comprehensive Review of Available Data

Current Levels of Environmental Exposure to Cadmium in Industrialized Countries as a Risk Factor for Kidney Damage in the General Population: A Comprehensive Review of Available Data

Cadmium-Tolerant Plant Growth-Promoting Bacteria Curtobacterium oceanosedimentum Improves Growth Attributes and Strengthens Antioxidant System in Chili (Capsicum frutescens)

Sensing Cd(II) Using a Disposable Optical Sensor Based on a Schiff Base Immobilisation on a Polymer-Inclusion Membrane. Applications in Water and Art Paint Samples

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