Chronic cannabis use and ERP correlates of visual selective attention during the performance of a flanker go/nogo task

Nicholls, C; Bruno, Raimondo; Matthews, Allison

doi:10.1016/j.biopsycho.2015.07.013

Cited by 15 publications

(9 citation statements)

References 71 publications

(122 reference statements)

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“…This is consistent with our data showing a decrease in the later P3 for implicit processing task which is most likely driven by early selective attentional processes. Our study however saw no differences behavioral measures whereas Nichols et al saw an increased reaction time response in cannabis users [ 46 ].…”

Section: Discussioncontrasting

confidence: 85%

“…Nichols et al used a flanker go/no go task to look at effects of early selective attention in cannabis users compared to controls. They showed a decrease in the N2 ERP associated with early selective attention in cannabis users compared to controls [ 46 ]. This is consistent with our data showing a decrease in the later P3 for implicit processing task which is most likely driven by early selective attentional processes.…”

Section: Discussionmentioning

confidence: 99%

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An Event-Related Potential Study on the Effects of Cannabis on Emotion Processing

et al. 2016

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The effect of cannabis on emotional processing was investigated using event-related potential paradigms (ERPs). ERPs associated with emotional processing of cannabis users, and non-using controls, were recorded and compared during an implicit and explicit emotional expression recognition and empathy task. Comparisons in P3 component mean amplitudes were made between cannabis users and controls. Results showed a significant decrease in the P3 amplitude in cannabis users compared to controls. Specifically, cannabis users showed reduced P3 amplitudes for implicit compared to explicit processing over centro-parietal sites which reversed, and was enhanced, at fronto-central sites. Cannabis users also showed a decreased P3 to happy faces, with an increase to angry faces, compared to controls. These effects appear to increase with those participants that self-reported the highest levels of cannabis consumption. Those cannabis users with the greatest consumption rates showed the largest P3 deficits for explicit processing and negative emotions. These data suggest that there is a complex relationship between cannabis consumption and emotion processing that appears to be modulated by attention.

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Section: Discussioncontrasting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

An Event-Related Potential Study on the Effects of Cannabis on Emotion Processing

et al. 2016

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Section: Discussionmentioning

confidence: 97%

“…The distribution of attention resources, the process of conflict monitoring, and the response inhibition are the important parts of attention, especially to sustained attention. Previous research using the AX‐CPT combined with ERPs suggested that Go‐N2 and Go‐P3 were related to the distribution of attention resources, Nogo‐N2 was related to the process of conflict monitoring, and Nogo‐P3 primarily reflected the response inhibition function (Guan et al., ; Nicholls, Bruno, & Matthews, ). Our study showed that patients with mTBI exhibited impairments in sustained attention, maybe due to the impairments of the distribution of attention resources and the process of conflict monitoring, sustained attention, and conflict monitoring, while response inhibition may have been spared.…”

Section: Discussionmentioning

confidence: 99%

Behavioral and neurophysiological abnormalities during cued continuous performance tasks in patients with mild traumatic brain injury

Zhao

Wang

et al. 2018

Brain and Behavior

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ObjectiveThis study's aim was to investigate the features and neural mechanisms of sustained attention in patients with mild traumatic brain injury (mTBI) by comparing and analyzing neuropsychological, behavioral, event‐related potentials, and event‐related desynchronization and synchronization between mTBI patients and healthy controls.MethodsTwenty mTBI patients with mTBI and 20 healthy controls underwent the Mini‐Mental State Examination (MMSE) and a cued continuous performance task (AX‐CPT). Neuropsychological, behavioral, and electroencephalogram (EEG) data were collected and analyzed.ResultsThere were significant differences between the mTBI group and the control group in their MMSE total scores, attention, and calculation, but there were no significant differences in orientation, memory, recall, and verbal scores. There were significant differences between the mTBI group and the control group in hitting the number, reaction time, and the number of errors of omission, but there were no significant differences in the number of false errors. The amplitude of Go‐N2 and Nogo‐N2 was significantly smaller for the mTBI group than that for the control group. The amplitude of Go‐P3 was significantly smaller for the mTBI group than that for the control group, but not for the amplitude of Nogo‐P3. The Go‐αERS were significantly less for the mTBI group than for the control group during the 0–200 ms after the stimulus onset. The Go‐αERD and Nogo‐αERD were significantly less for the mTBI group than for the control group during the 600–1,000 ms after the stimulus onset. The Go‐βERS were significantly less for the mTBI group than for the control group during the 200–400 ms after the stimulus onset. There were no significant differences in the Nogo‐αERS and Nogo‐βERD/ERS between the mTBI group and the control group.ConclusionPatients with mTBI exhibited impairments in sustained attention and conflict monitoring, while response inhibition may have been spared.

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“…Interestingly, the difference in marijuana use by teens with PCE was largely driven by a greater number of males compared to girls with PCE. Given findings indicating that marijuana use among teens increases risk for psychosis (Green et al, 2016), poorer visual selective attention (Nicholls et al, 2015), lower academic achievement (Arria et al, 2015; Bechtold et al, 2016), and reduction in cortical thickness (Mashhoon et al, 2015), males with PCE could be at increased risk for negative effects of marijuana use. However, additional studies considering use quantity, frequency and/or marijuana use disorder symptoms would provide important clarifying information.…”

Section: Discussionmentioning

confidence: 99%

The association of prenatal cocaine exposure, externalizing behavior and adolescent substance use

Minnes

Min

Kim

et al. 2017

Drug and Alcohol Dependence

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Prenatal cocaine exposure (PCE) may increase adolescent substance use through alterations of neurotransmitter systems affecting fetal brain development. The relationship between PCE and substance use at 15 and 17 years was examined. Subjects (365: 186 PCE; 179 non-cocaine exposed (NCE)) supplied biologic and self-report data using the Youth Risk Behavior Surveillance System (YRBSS) and Computerized Diagnostic Interview Schedule for Children (C-DISC 4) at ages 15 and 17. The relationship between PCE and substance use was assessed using General Estimating Equation (GEE) analyses controlling for confounding factors including violence exposure and preschool lead level. Teens with PCE vs. NCE teens were 2 times more likely to use tobacco (OR = 2.1; 95% CI 1.21–3.63; p < .001) and marijuana (OR = 1.85; CI 1.18–2.91; p < .001) and have a substance use disorder at age 17 (OR = 2.51; CI 1.00–6.28; p < .05). Evaluation of PCE status by gender revealed an association between PCE and marijuana use that was more pronounced for boys than girls at 17 years. Violence exposure was also a significant predictor of alcohol (p < .001), tobacco (p < .05), and marijuana (p < .0006) use and substance abuse/dependence (p < .01). Externalizing behavior at age 12 fully mediated the effects of PCE on substance use disorder at age 17 and partially mediated effects of PCE on tobacco use, but did not mediate effects on marijuana use. The percentage of substance use reported increased between 15 and 17 years, with no differences between the PCE and NCE groups. Data suggest specialized drug use prevention measures for children with PCE may benefit this high risk group.

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Chronic cannabis use and ERP correlates of visual selective attention during the performance of a flanker go/nogo task

Cited by 15 publications

References 71 publications

An Event-Related Potential Study on the Effects of Cannabis on Emotion Processing

An Event-Related Potential Study on the Effects of Cannabis on Emotion Processing

Behavioral and neurophysiological abnormalities during cued continuous performance tasks in patients with mild traumatic brain injury

The association of prenatal cocaine exposure, externalizing behavior and adolescent substance use

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