Chronic Cholecystitis

Nesland, Jahn M.

doi:10.1080/01913120490489441

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…Patients with chronic cholecystitis usually do not require antibiotics. However, it is important to use antibiotics appropriately when the patient has a combination of underlying diseases, especially if there is impairment of liver or kidney function [ 12 ]. However, when surgery is indicated, surgical removal of the gallbladder is the treatment of choice [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Effect of Laparoscopic Cholecystectomy on Patients with Cholecystolithiasis Complicated with Chronic Cholecystitis and Postoperative Quality of Life

Song

Chen

Lin

2022

Evidence-Based Complementary and Alternative Medicine

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Objective. To assess the treatment outcome and postoperative quality of life of patients with gallbladder stones and chronic cholecystitis after open cholecystectomy and laparoscopic cholecystectomy. Methods. Between 2018 and 2020, 108 patients with gallbladder stones and chronic cholecystitis treated in our hospital were assessed for eligibility and randomly recruited. They were concurrently assigned (1 : 1) to receive either open cholecystectomy (control group) or laparoscopic cholecystectomy (study group). Outcome measures include surgical indices, inflammatory response, postoperative complications, and quality of life of patients. Results. Laparoscopic cholecystectomy was associated with a shorter duration of surgery, intraoperative bleeding, time to first postoperative bowel movement, and postoperative hospital stay versus open cholecystectomy ( P < 0.05 ). The levels of inflammatory factors of all eligible patients were comparable before cholecystectomy ( P > 0.05 ). The patients given laparoscopic cholecystectomy showed lower levels of C-reactive protein (CRP), interleukin (IL)-6, and IL-8 versus those given open cholecystectomy ( P < 0.05 ). Laparoscopic cholecystectomy resulted in a significantly lower incidence of complication (3.56%) versus open cholecystectomy (24.07%) ( P < 0.05 ). The patients had significantly higher physical, psychological, and social function scores after laparoscopic cholecystectomy versus open cholecystectomy ( P < 0.05 ). Conclusion. Laparoscopic cholecystectomy provides better surgical results, mitigates the inflammatory response, lowers the incidence of complications, and improves the quality of life of patients versus open cholecystectomy, so it is worthy of application in clinical treatment.

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Section: Introductionmentioning

confidence: 99%

Therapeutic Effect of Laparoscopic Cholecystectomy on Patients with Cholecystolithiasis Complicated with Chronic Cholecystitis and Postoperative Quality of Life

Song

Chen

Lin

2022

Evidence-Based Complementary and Alternative Medicine

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“…However, the mechanisms leading to this pathology are not fully understood [2]. In light of recent studies, chronic inflammatory conditions are tightly related to tissue procoagulation state [3].…”

Section: Introductionmentioning

confidence: 99%

“…Chronic cholecystitis is characterised by chronic inflammation of a gallbladder mucosa and it is usually associated with gallstones [ 1 ]. However, the mechanisms leading to this pathology are not fully understood [ 2 ]. In light of recent studies, chronic inflammatory conditions are tightly related to tissue procoagulation state [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Tissue Factor and Tissue Factor Pathway Inhibitor in Chronically Inflamed Gallbladder Mucosa

Liczko

Stawski²,

Żaba

et al. 2014

BioMed Research International

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We characterised a tissue factor (TF) and tissue factor pathway inhibitor (TFPI) expression in relation to severity of inflammatory infiltration of the gallbladder mucosa in a chronic cholecystitis. We prospectively studied the gallbladder specimens obtained from 54 patients who had undergone cholecystectomy due to chronic calculous cholecystitis and 16 calculosis-free gallbladder specimens obtained from patients who underwent cholecystectomy due to the polyp/polyps as well as in cases of gallbladder injury. To assess TF and TFPI immunoreactivity by immunohistochemistry, the monoclonal anti-human TF and TFPI antibodies were used. The inflammatory infiltration of the gallbladder mucosa was reflected by the number of CD3 and CD68 positive cells. The expression of TF and TFPI differed significantly between the cholecystitis and the control group. Most capillary endothelial cells of the cholecystitis group presented weak expression for TFPI. The mean number of CD3 positive lymphocytes in the cholecystitis group was 18.6 ± 12.2, but the mean number of CD68 positive cells was 29.7 ± 13.9. In the control sections, it was 3.1 ± 1.9 and 8.8 ± 3.9, respectively (P < 0.001). The results of the current study suggest that the tissue procoagulant state found may be engaged in the etiopathogenesis of the cholecystitis.

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Gallstones and Benign Gallbladder Disease

Pitchumoni

Ravindran

2021

Geriatric Gastroenterology

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Chronic Cholecystitis

Cited by 4 publications

References 7 publications

Therapeutic Effect of Laparoscopic Cholecystectomy on Patients with Cholecystolithiasis Complicated with Chronic Cholecystitis and Postoperative Quality of Life

Therapeutic Effect of Laparoscopic Cholecystectomy on Patients with Cholecystolithiasis Complicated with Chronic Cholecystitis and Postoperative Quality of Life

Tissue Factor and Tissue Factor Pathway Inhibitor in Chronically Inflamed Gallbladder Mucosa

Gallstones and Benign Gallbladder Disease

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