Chronic diarrhoea-all in the bowel?

Gupta, Sanjay; Tibbs, C. J.; Farthing, M. J. G.; Pollok, Richard

doi:10.1258/jrsm.100.8.379

Journal of the Royal Society of Medicine

2007

DOI: 10.1258/jrsm.100.8.379

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Chronic diarrhoea-all in the bowel?

Sanjay Gupta

C. J. Tibbs

M. J. G. Farthing

et al.

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Cited by 3 publications

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References 26 publications

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“…I thank Mr Marston for his comments regarding our article (JRSM 2007;100: 379). 1 He raises two issues. Regarding the first, I agree that the patient may have been saved from all the invasive investigations if the thyromegaly and cervical lymph node enlargement had been identified earlier.…”

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confidence: 99%

Chronic diarrhoea-author's response

Gupta¹

2007

J R Soc Med

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mentioning

confidence: 99%

Chronic diarrhoea-author's response

Gupta¹

2007

J R Soc Med

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Chronic diarrhoea

Marston¹

2007

J R Soc Med

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Small Cell Variant of Medullary Thyroid Carcinoma: A Possible Treatment

Sherret

Alomari

Coleman

et al. 2020

Cureus

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Small cell variant of medullary thyroid carcinoma is an extremely rare histologic entity with a paucity of data. As such, there is a lack of literature and clinical experience regarding this disease. In this report, we examine a case of small cell variant of medullary thyroid carcinoma that presented with intractable nausea, vomiting and diarrhea. While these symptoms were essentially refractory to the standard symptomatic treatment, further laboratory analysis revealed dramatically elevated calcitonin levels and mildly raised thyroid-stimulating hormone levels. Interestingly, repletion of thyroid hormone and treatment with lanreotide resulted in an abatement of our patient's symptoms. This temporal clinical improvement highly suggests a potential role involving thyroid-stimulating hormone and calcitonin levels in the pathogenesis of this disease, and consequently suggests a role for thyroxine in treating the associated gastrointestinal symptoms.

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Chronic diarrhoea-all in the bowel?

Cited by 3 publications

References 26 publications

Chronic diarrhoea-author's response

Chronic diarrhoea-author's response

Chronic diarrhoea

Small Cell Variant of Medullary Thyroid Carcinoma: A Possible Treatment

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