Chronic disease comorbidity in patients with oral leukoplakia: A matched case–control study

Giudice, Lance W; Graff, Emrik A; Haripersad, Yasmita; Frydrych, Agnieszka; Parsons, Richard; Kujan, Omar; Farah, Camile S.

doi:10.1111/odi.13315

Cited by 4 publications

(6 citation statements)

References 51 publications

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“…is is depicted in the present study where 12.6% of participants reported visiting the dental hospital because of oral lesions. e literature indicates that systemic diseases are associated with oral lesions [29,30]. For instance, oral ulceration may be a sign of underlying systemic conditions [30].…”

Section: Discussionmentioning

confidence: 99%

“…For instance, oral ulceration may be a sign of underlying systemic conditions [30]. Likewise, certain chronic conditions such as dyslipidemia and asthma are independently associated with oral leukoplakia [29]. Given the challenges of diagnosing and treating oral lesions due to remarkable similarities in their clinical appearance, it is crucial for clinicians to have a clear understanding of the distribution and clinical presentations of oral lesions for the provision of quality oral care.…”

Section: Discussionmentioning

confidence: 99%

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Medical Conditions, Oral Health Practices, and Barriers to Treatment among Patients Visiting a Teaching Dental Hospital in Eastern Saudi Arabia

Alonaizan

Almas

Nazir

et al. 2022

The Scientific World Journal

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Objective. To assess the prevalence of medical conditions, oral hygiene practices, and dental visits among patients who attended a teaching dental hospital in Dammam, Saudi Arabia. Materials & Methods. This retrospective cross-sectional study used patient records from 2009 to 2015 from the dental hospital of the College of Dentistry Imam Abdulrahman Bin Faisal University, Dammam. Patients’ demographics, medical history, oral hygiene practices, reasons for attending the facility, attendance patterns, and smoking habits were studied. Results. The study included 1502 records of patients with 65.1% of males and 34.9% of females. The prevalence of medical conditions was 25.7% in the study. The most common medical conditions included diabetes mellitus (7.2%), hypertension (6.5%), and anemia (4.7%). Only 21.8% reported visiting the dental hospital in the past one year. The prevalence of smoking was 16.7%, and this did not differ significantly between healthy and medically compromised patients ( P = 0.165 ). Fillings were the most common (21.6%) reason for visiting a dental hospital, followed by treatment for periodontal problems (12.9%) and oral lesions (12.6%), whereas treatment for braces (orthodontics) was the least common (5%) reason for visiting the hospital. The reasons for visiting the hospital did not differ significantly between healthy and medically compromised patients ( P > 0.05 ). The three most common barriers to dental visits included long waiting time (18.1%), fear of dental treatment (14.4%), and difficulty in getting an appointment (11.3%). Conclusion. The study showed that dental patients had a high prevalence of medical conditions. Diabetes mellitus was the most prevalent problem. Most patients visited the dental hospital to receive restorative treatment, and a long waiting time was the most common barrier to dental visits. Public health measures should be taken to improve the general health and oral care of patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Medical Conditions, Oral Health Practices, and Barriers to Treatment among Patients Visiting a Teaching Dental Hospital in Eastern Saudi Arabia

Alonaizan

Almas

Nazir

et al. 2022

The Scientific World Journal

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“…9 Similarly, chronic diseases have been identified to be more common in patients with OPMDs; for instance, dyslipidemia and asthma have been identified as being more prevalent in patients with oral leukoplakia in comparison to case-controls. 10 Furthermore, elderly patients (≥75 years of age) who develop oral leukoplakia have a higher 5-year cumulative incidence (3.21%) for the development of oral cancer. 5 Tobacco use has also been identified in increasing the risk for adverse events in patients with COVID-19.…”

Section: Considerations For the Evaluation Of New And Established Pmentioning

confidence: 99%

Considerations in the evaluation and management of oral potentially malignant disorders during the COVID‐19 pandemic

et al. 2020

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Aim: The COVID-19 pandemic has resulted in society experiencing unprecedented challenges for health care practitioners and facilities serving at the frontlines of this pandemic. With regard to oral cancer, there is a complete absence of literature regarding the long-term impact of pandemics on patients with oral potentially malignant disorders (OPMDs). The objective of this article is to put forth an institutional multidisciplinary approach for the evaluation and management of OPMDs. Methods: A multidisciplinary approach was put formalized within our institution to risk stratify patients based on need for in-person assessment vs telehealth assessment during the COVID-19 pandemic. Results: With judicious risk stratification of patients based on clinical features of their OPMD and with consideration of ongoing mitigation efforts and regional pandemic impact, providers are able to safely care for their patients. Conclusions:The COVID-19 pandemic has required health care practitioners to make novel decisions that are new to us with development of creative pathways of care that focused on patient safety, mitigation efforts, and clinical management of disease processes. The care of patients with OPMDs requires special considerations especially as patients at high risk for severe illness are also higher risk for the development of OPMDs.

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“…In the interest of improving patient care, it is important to recognise that individual's psychological and social well‐being appears to be most significantly compromised at the time of diagnosis and it is at this time in particular that support should be provided. Diagnosis of OPMDs has been associated with increased levels of anxiety in view of the cancer risk and the uncertainty surrounding disease progression, stability or regression 19,20 . Improvements in life quality over time may be attributed to progressive patient acceptance of their disease and adaptation to their affliction.…”

Section: Discussionmentioning

confidence: 99%

Changes in quality of life over time in patients diagnosed with oral leukoplakia: A prospective longitudinal study

Frydrych

Schaijik

Parsons

et al. 2023

J Oral Pathology Medicine

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Background: Oral leukoplakia (OL) is one of the most prevalent oral potentially malignant disorders (OPMD). Although there is emerging evidence that quality of life (QoL) is impaired in subjects with OL; studies to date are based on single and heterogenous point-in-time assessments. The aim of this study was to ascertain if QoL scores change over time in individuals diagnosed with OL.Methods: Forty-one individuals with OL were administered the Short Generic Health Questionnaire (SF-12) and the discipline-specific Oral Potentially Malignant Disorder Questionnaire (OPMDQ) at four points in time: at the time of clinical diagnosis, at the post-biopsy review (confirmed diagnosis), and at 3-and 6-month follow-up appointments. Responses were compared between the four time points.Results: No significant differences were observed in the SF-12 questionnaire scores over time. However, a general improvement in the participants' life quality was evident over the 6-month period under investigation in the domains of psychological and social well-being (p = 0.0027) and effect of treatment on daily life (p = 0.0317) as well as in the total score (p = 0.0005) of the OPMDQ. Age, gender, medical status, tobacco/alcohol use, lesion site, size, the presence of dysplasia and treatment did not impact QoL scores over time.Conclusions: QoL scores of OL subjects may improve with time. Our results suggest that studies examining QoL in individuals with OL should be controlled for time at which the participants are surveyed.change, longitudinal study, oral leukoplakia, oral potentially malignant disorder, quality of life | INTRODUCTIONOral potentially malignant disorders (OPMDs) refer to "any oral mucosal abnormality that is associated with a statistically increased risk of developing oral cancer." 1 Oral leukoplakia (OL) is among the most prevalent OPMDs and defined as a predominantly white plaque of questionable risk having excluded other known diseases or disorders that carry no increased risk for cancer. 2,3 Diagnosis is based on clinical presentation and histopathology (keratosis with no/mild/moderate/ severe dysplasia). 1 The aetiology of OL is complex and not fully understood, with tobacco and alcohol use considered important risk factors. 4 The global prevalence is estimated to be 2% with a reported Australian average annual malignant transformation rate of about 1%. 2,5,6 Management of OL remains a challenge given difficulties

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Chronic disease comorbidity in patients with oral leukoplakia: A matched case–control study

Cited by 4 publications

References 51 publications

Medical Conditions, Oral Health Practices, and Barriers to Treatment among Patients Visiting a Teaching Dental Hospital in Eastern Saudi Arabia

Medical Conditions, Oral Health Practices, and Barriers to Treatment among Patients Visiting a Teaching Dental Hospital in Eastern Saudi Arabia

Considerations in the evaluation and management of oral potentially malignant disorders during the COVID‐19 pandemic

Changes in quality of life over time in patients diagnosed with oral leukoplakia: A prospective longitudinal study

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