Chronic Effect Of Photobiomodulation Therapy On Muscle Function In Persons With Multiple Sclerosis

Abstract

Muscle weakness and fatigue are two disabling symptoms of Multiple Sclerosis (MS). Photobiomodulation therapy (PBMT) using red/near-infrared light is an emerging therapeutic modality thought to improve endurance or strength in healthy populations. Previously presented work revealed that a single acute high energy dose of PBMT may improve muscle force recovery in persons with MS (PwMS). PURPOSE: To investigate the effect of extended PBMT at an optimal dose of energy on muscle strength and endurance during a fatiguing contraction in PwMS. METHODS: Randomized crossover design. Persons with mild-moderate relapsing-remitting MS (n=12, F=11) were recruited. Participants applied PBMT (active or placebo) to the gastrocnemius and Tibialis Anterior (TA) muscles of both legs twice a day. The optimal dose of energy of the active device for each participant was 40J, 80J, or 120J as determined individually from preliminary studies. The effect of PBMT on muscle function was assessed in five sessions, pre-and post-treatment, and post-washout. The measurements comprised three maximal voluntary contractions (MVCs) of the right TA, followed by an intermittent contraction at 50% MVC to task failure. The measurements were obtained at baseline, after which

Evaluation of thermal shock therapy for reducing pain during intense pulsed light therapy: An intrapatient randomized controlled study

“…IPL causes tissue local heat accumulation and initiates a skin inflammatory response through photothermal and photochemical effects. This can result in a range of symptoms, including itching, erythema, skin desquamation, and skin irritation 26 . Thermal shock therapy has adequate heat abstraction capabilities, inducing vascular constriction and reducing nerve conduction velocity to alleviate the sensation of pain.…”

“…This can result in a range of symptoms, including itching, erythema, skin desquamation, and skin irritation. 26 Thermal shock therapy has adequate heat abstraction capabilities, inducing vascular constriction and reducing nerve conduction velocity to alleviate the sensation of pain. On the contrary, capillary constriction slows blood flow, lowers tissue temperature and cellular metabolism, thereby inhibiting the spread of inflammation.…”