Chronic Eosinophilic Pneumonia

Robertson, Charles L.; Shackelford, Gary D.; Armstrong, John D.

doi:10.1148/101.1.57

Cited by 9 publications

(2 citation statements)

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“…Patchy, homogeneous, nonsegmental infiltrates appear and disappear in unpredictable fashion and have a tendency to recur in the same loca tions [11,20]. A characteristic picture is one of dense peripheral infil trates often involving the entire 'cortex' of the lung leaving but a center of perihilar aeration.…”

Section: Roentgenologymentioning

confidence: 99%

Chronic Eosinophilic Pneumonia

et al. 1975

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An association betwen migratory pulmonary infiltrates and peripheral eosinophilia has been known for at least 40 years. Diagnostic challenges still exist in the classifications within this syndrome. We describe a 33-year-old female without asthma but with definite ‘atopy’ who had a 4-year history of recurring pulmonary lesions. These were sometimes segmental, at other times dense and peripheral, and once there was lobar atelectasis due to mucoid impaction. Diagnosis by lung biopsy revealed eosinophilic pneumonia with bronchiolitis obliterans as a prominent feature. Steroid treatment resulted in prompt improvement; during a 5-year follow-up the infiltrates have not recurred but there has been persistent mild obstruction.

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Section: Roentgenologymentioning

confidence: 99%

Chronic Eosinophilic Pneumonia

et al. 1975

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“…CEP predominantly occurs in middle-aged women, and common symptoms include cough, fever, dyspnoea, fatigue and malaise [3,4]. In the peripheral lungs, the imaging features of CEP consist of multiple patchy infiltrations with ill-defined margins [5][6][7][8][9][10][11][12], and spontaneous migration of these infiltrates occurs in approximately 25% of patients [13]. Diagnosis relies on clinical signs, typical imaging findings and blood and/or alveolar eosinophilia once other aetiological diagnoses have been excluded.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of short-term prednisolone treatment in patients with chronic eosinophilic pneumonia

et al. 2015

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In patients with chronic eosinophilic pneumonia (CEP), dramatic improvements are seen in response to corticosteroid therapy; however, relapse is common after treatment has ceased. The optimal duration of corticosteroid therapy remains unclear.In a randomised, open-label, parallel group study, eligible patients with CEP received oral prednisolone for either 3 months (3-month group) or 6 months (6-month group), followed by 2 years observation. All patients were treated with an initial dose of prednisolone of 0.5 mg·kg −1 ·day −1, which was then tapered and discontinued at either 3 or 6 months. The primary end-point was relapse during the follow-up period.In the final analysis, there were 23 patients in the 3-month group and 21 patients in the 6-month group. All patients showed a good response to prednisolone treatment. There were 12 (52.1%) relapses in the 3-month group and 13 (61.9%) relapses in the 6-month group. No significant difference was found in the cumulative rate of relapse ( p=0.56). All relapse cases showed improvement upon resumption of prednisolone treatment.No difference was observed in the rate of relapse between the 3-and 6-month prednisolone treatment groups for patients with CEP. @ERSpublications Short-term, 3 month, prednisolone treatment is a therapeutic option for chronic eosinophilic pneumonia

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Lungenveränderungen auf immunologischer Basis

Majewski¹,

Stender²

1989

Handbuch Der Medizinischen Radiologie / Encyclopedia of Medical Radiology

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Chronic Eosinophilic Pneumonia

Cited by 9 publications

References 0 publications

Chronic Eosinophilic Pneumonia

Chronic Eosinophilic Pneumonia

Efficacy of short-term prednisolone treatment in patients with chronic eosinophilic pneumonia

Lungenveränderungen auf immunologischer Basis

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