2015
DOI: 10.1016/j.etap.2015.02.016
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Chronic exposure to cigarette smoke causes extrapulmonary abnormalities in rats

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Cited by 20 publications
(13 citation statements)
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“…These results agree well with previous reports of weight and muscle strength loss in COPD mice exposed to cigarette smoke [25]. They are also consistent with the observations of Kamiide et al [33], who show COPD rats exhibit substantially weaker grips than normal rats. However, the 16-week CSE did not affect NAGS in MG rats.…”
Section: Effect Of Smoke Exposure On the Skeletal Muscles Of Ratssupporting
confidence: 93%
“…These results agree well with previous reports of weight and muscle strength loss in COPD mice exposed to cigarette smoke [25]. They are also consistent with the observations of Kamiide et al [33], who show COPD rats exhibit substantially weaker grips than normal rats. However, the 16-week CSE did not affect NAGS in MG rats.…”
Section: Effect Of Smoke Exposure On the Skeletal Muscles Of Ratssupporting
confidence: 93%
“…As expected, smoking caused emphysema (23), reduced food intake (24,25) and lowered body weight (23,(26)(27)(28)(29). While reduced food intake could only partially explain the lowered body weight, as previously reported (24), loss of fat mass (28) and reduced lean mass and body growth also contribute to body weight loss.…”
Section: Discussionsupporting
confidence: 65%
“…They develop COPD-like lesions and emphysema-like airspace enlargement within a few months of active CS exposure. By contrast, rat strains seem to be more resistant to the induction of emphysema-like lesions [80][81][82][83]. Equally, animal sex has been reported as a confounding factor in COPD susceptibility.…”
Section: Smoke Exposure Modelsmentioning
confidence: 99%