Chronic exposure to diclofenac on two freshwater cladocerans and Japanese medaka

Lee, Jin Young; Ji, Kyunghee; Kho, Younglim; Kim, Pilje; Choi, Kyungho

doi:10.1016/j.ecoenv.2011.03.014

Cited by 110 publications

(48 citation statements)

References 32 publications

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“…Furthermore, a 3-month exposure time of fish to 0.001-10 mg/L of diclofenac caused a lower hatching success and a delay in hatch [85]. Diclofenac did not cause any effects to early-life stages of D. rerio.…”

Section: Nonsteroidal Anti-inflammatory Drugs: the Example Of Diclofementioning

confidence: 86%

Bioassays Currently Available for Evaluating the Biological Potency of Pharmaceuticals in Treated Wastewater

Vasquez

Michael²,

Kümmerer

et al. 2015

The Handbook of Environmental Chemistry

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Water deprivation with regard to quantity and quality is one of the most important environmental problems of the century. The increasing demand of water resources puts pressure on the utilization of alternative sources such as treated wastewater. In the context of "reduce, reuse, and recycle," the inclusion of treated wastewater in the water cycle seems a promising practice for water management. The lack of general acceptance of stakeholders and public, however, still hinders the widespread application of wastewater reuse. A reason for this is, among others, the presence of contaminants of emerging concern in treated wastewater. This has led to an increased concern about direct and indirect effects to the environment and possible implications to human health. The development and application of bioassays able to identify and quantify the biological potency of treated wastewater is an ongoing research effort, especially when taking into consideration that a plethora of contaminants exist and interact in this complex matrix. This chapter summarizes available literature regarding the sensitivity of currently applied bioassays for assessing biological effects of treated wastewater and their correlation with chemical analysis. The focus is on pharmaceuticals since they represent one of the major groups of contaminants of emerging concern with many unanswered questions currently in place.

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Section: Nonsteroidal Anti-inflammatory Drugs: the Example Of Diclofementioning

confidence: 86%

Bioassays Currently Available for Evaluating the Biological Potency of Pharmaceuticals in Treated Wastewater

Vasquez

Michael²,

Kümmerer

et al. 2015

The Handbook of Environmental Chemistry

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“…While this species has been employed in toxicity evaluation of chronic exposure as well (Han et al 2010;Lee et al 2011), a standardized chronic toxicity test protocol for this species is not currently available. Careful review of available articles shows that M. macrocopa was generally used either as a component of a freshwater community or under varying test conditions, e.g., with different temperature or feeding schedules.…”

Section: Introductionmentioning

confidence: 99%

Optimal conditions for three brood chronic toxicity test method using a freshwater macroinvertebrate Moina macrocopa

Choi

2011

Environ Monit Assess

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Freshwater cladocera such as Daphnia magna and Ceriodaphnia dubia have been used extensively for freshwater toxicity test worldwide. However, these species may not be indigenous in certain geographical regions, which restrict the utility of these organisms as test species. In the present study, we investigated optimal culture and test conditions for an indigenous freshwater macroinvertebrate of Korea, Moina macrocopa. The culture conditions that were evaluated included water temperature (20°C and 25°C), rearing media (moderately hard water or MHW, with or without selenium supplementation, or Elendt M4), and food density (2.5 × 10(7) and 5 × 10(7) cells/mL of Selenastrum capricornutum), and their effects on the life history characteristics of M. macrocopa were determined. Population growth rate of M. macrocopa was maximized at 25°C with 5 × 10(7) cells/mL of algal food density in MHW. A series of chronic three brood reference toxicant tests were conducted under the ideal culture conditions that were identified here, and the results of the tests indicated reliable reproducibility of the test protocol. Optimal culture and test conditions that were identified for M. macrocopa in the present study are suggested for evaluation of chronic toxicity of chemicals and industrial or municipal discharge.

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“…(Stumpf et al 1999;Ashton et al 2004). Adverse effect of DCF contamination on vulture and aquatic species can be noticed, as declination in populations of vultures in the Indian subcontinent (Shulzt et al 2004) and Southern African wild (Naidoo et al 2009) and decrease in reproduction of fish (Lee et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Aqueous degradation kinetics of pharmaceutical drug diclofenac by photocatalysis using nanostructured titania–zirconia composite catalyst

Das

Barodia

Sengupta

et al. 2014

Int. J. Environ. Sci. Technol.

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Diclofenac (DCF) is an anti-inflammatory pharmaceutical drug, and its presence in a trace amount in waste water makes severe environmental pollution. The degradation of DCF was investigated by a photocatalytic process in presence of ultra violet irradiation at room temperature using titania and titania-zirconia nanocomposite catalysts in a batch reactor. The composite catalyst was prepared by sol-gel method and characterized by X-ray diffraction, transmission electron microscopy as well as BET surface area analyzer. The effect of various process parameters such as catalyst loading, initial concentration of DCF and pH of the experimental solution was observed on the degradation of DCF. The titania-zirconia nanocomposites exhibited reasonably higher photocatalytic activity than that of anatase form of titania without zirconia. The maximum removal of DCF of about 92.41 % was achieved using Zr/Ti mass ratio of 11.8 wt% composite catalyst. A rate equation was proposed for the degradation of DCF using the composite catalyst. The values of rate constant (k c ) and adsorption equilibrium constant (K 1 ) were found to vary with the catalyst content in the reaction mixture.

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Chronic exposure to diclofenac on two freshwater cladocerans and Japanese medaka

Cited by 110 publications

References 32 publications

Bioassays Currently Available for Evaluating the Biological Potency of Pharmaceuticals in Treated Wastewater

Bioassays Currently Available for Evaluating the Biological Potency of Pharmaceuticals in Treated Wastewater

Optimal conditions for three brood chronic toxicity test method using a freshwater macroinvertebrate Moina macrocopa

Aqueous degradation kinetics of pharmaceutical drug diclofenac by photocatalysis using nanostructured titania–zirconia composite catalyst

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