Chronic fungal vaginitis: The value of cultures

Nyirjesy, Paul; Seeney, Sueny M.; Grody, Marvin H. Terry; Jordan, Carol A.; Buckley, Helen R.

doi:10.1016/0002-9378(95)90347-x

Cited by 121 publications

(80 citation statements)

References 5 publications

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“…3,8,9 Several studies in other centers suggested that these infections were caused by an inappropriate use of antifungal. [8][9][10] However, we failed to show this association in this study.…”

Section: Discussioncontrasting

confidence: 69%

“…albicans C. non-albicans Mix Total n(%) p RO; CI (95%) n (%) n (%) n (%) 10 But recurrent infections during the last one year did not seem to correlate with C. non-albicans VVC. Opposite finding was reported by Sobel et al 8 The cause of this difference is not well understood, but the infection pattern in different region might have influence the results.…”

Section: Objective Findingsmentioning

confidence: 88%

“…7,10,17,18 VVC patients can transmit the infection to her partner 17,18 but, relationship between C. non-albicans infection and the partner's symptoms is not known. Table 4.…”

Section: Discussionmentioning

confidence: 99%

“…The most common non-albicans species are: Candida glabrata, followed by Candida tropicalis and Candida parapsilosis. [6][7][8][9][10] 143 C. non-albicans infection now becomes a medical problem, due to the increasing prevalence especially in immunocompromised patients, the emergence of newly recognized pathogens, the discovery of resistance species to anti-fungal azoles as well as recurrent infections. 8,9,11 It is also suggested to be associated with inadequate treatment with broad spectrum anti-fungal.…”

mentioning

confidence: 99%

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Vulvovaginal candidosis caused by Candida non-albicans, proportion and clinical characteristics in the Dr. Cipto Mangunkusumo National General Hospital, Jakarta

Haryani¹,

Urip²,

Wasitaatmadja³

2003

Med J Indones

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Section: Discussioncontrasting

confidence: 69%

Section: Objective Findingsmentioning

confidence: 88%

“…7,10,17,18 VVC patients can transmit the infection to her partner 17,18 but, relationship between C. non-albicans infection and the partner's symptoms is not known. Table 4.…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Vulvovaginal candidosis caused by Candida non-albicans, proportion and clinical characteristics in the Dr. Cipto Mangunkusumo National General Hospital, Jakarta

Haryani¹,

Urip²,

Wasitaatmadja³

2003

Med J Indones

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“…5-10 %), Candida tropicalis (5-10 %), Candida parapsilosis and Candida krusei (2-5 %), are less common pathogens in vaginitis. However, a significant increase in non-albicans species (up to 20-30 % in some cases) has been reported to be associated with recurrent candidiasis (Nyirjesy et al, 1995).…”

Section: Introductionmentioning

confidence: 99%

Genetic relatedness of Candida strains isolated from women with vaginal candidiasis in Malaysia

Chong

Lee

Tan

et al. 2003

Journal of Medical Microbiology

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The aims of this study were to compare the genetic relatedness of: (i) sequential and single isolates of Candida strains from women with recurrent vaginal candidiasis (RVC); and (ii) Candida strains from women who had only one episode of infection within a 1-year period. In total, 87 isolates from 71 patients were cultured, speciated and genotyped by random amplification of polymorphic DNA (RAPD) analysis. Patients were categorized into three groups, namely those with: (i) a history of RVC from whom two or more yeast isolates were obtained (group A); (ii) a history of RVC from whom only a single isolate was obtained (group B); and (iii) a single episode of vaginal candidiasis within a 1-year period (group C). Six yeast species were detected: Candida albicans, Candida glabrata, Candida lusitaniae, Candida famata, Candida krusei and Candida parapsilosis. Interestingly, the prevalence of non-albicans species was higher in group A patients (50 %) than in patients in groups B (36 %) or C (18·9 %). Eighty RAPD profiles were observed, with a total of 61 polymorphic PCR fragments of distinct sizes. Clustering analysis showed that, overall, the majority of patients in group A had recurrent infections caused by highly similar, but not identical, sequential strains [mean pairwise similarity coefficient (S AB ) ¼ 0·721 AE 0·308]. The range of mean S AB values for intergroup comparisons for C. albicans isolates alone was 0·50-0·56, suggesting that there was no significant relatedness between strains from different groups. Genetic similarity of C. albicans isolates from patients in group A was lower than that of C. albicans isolates from patients in group C (mean S AB ¼ 0·532 AE 0·249 and 0·636 AE 0·206, respectively); this difference was statistically significant (P ¼ 0·036). These results demonstrate that the cause of recurrent infections varies among individuals and ranges between strain maintenance, strain microevolution and strain replacement; the major scenario is strain maintenance with microevolution. They also show that C. albicans strains that cause recurrent infections are less similar to each other than strains that cause one-off infections, suggesting that the former may represent more virulent subtypes.

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Boric acid vaginal suppositories: A brief review

Prütting

Cerveny

1998

Infect. Dis. Obstet. Gynecol.

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Chronic fungal vaginitis: The value of cultures

Cited by 121 publications

References 5 publications

Vulvovaginal candidosis caused by Candida non-albicans, proportion and clinical characteristics in the Dr. Cipto Mangunkusumo National General Hospital, Jakarta

Vulvovaginal candidosis caused by Candida non-albicans, proportion and clinical characteristics in the Dr. Cipto Mangunkusumo National General Hospital, Jakarta

Genetic relatedness of Candida strains isolated from women with vaginal candidiasis in Malaysia

Boric acid vaginal suppositories: A brief review

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