Chronic Gastrointestinal Bleeding

Muñoz-Navas, Miguel; Ibáñez, Maite Betés

doi:10.1016/b978-1-4377-1529-3.00016-6

Cited by 5 publications

(5 citation statements)

References 310 publications

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“…Angiodysplasia is an arterio-venous malformation of colonic mucosa and sub mucosa that is characterised by markedly dilated and tortuous submucosal veins with replacement of overlying mucosa by collection of thinwalled venules and capillaries. Literature suggests that the colon is one of the most frequent sites for of angiodysplasia [5,6]. Angiodysplasia of the colon was first reported as a hemangioma of the sigmoid colon in mid-nineties by Holman et al, and Marguillis, et al [7,8].…”

Section: Discussionmentioning

confidence: 99%

Angiodysplasia of Left Colon Extending to Anal Verge Landed Patient into Apr: A Rare Diagnosis

Gaurav¹

2020

J Clin Stud Rev Rep

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Section: Discussionmentioning

confidence: 99%

Angiodysplasia of Left Colon Extending to Anal Verge Landed Patient into Apr: A Rare Diagnosis

Gaurav¹

2020

J Clin Stud Rev Rep

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“…Literature suggests that the colon is one of the most frequent sites for of angiodysplasia. 5,6 Angiodysplasia of the colon was first reported as a hemangioma of the sigmoid colon in midnineties by Holman et al, and Marguillis, et al 7,8 Angiodysplasia of colon is recognized as an important cause of lower gastro-intestinal bleeding in the elderly. 9 However, it may occur anywhere in the gastro-intestinal tract, but most of the angiodysplasias are located at the cecum and right side of the colon.…”

Section: Discussionmentioning

confidence: 99%

Angiodysplasia of left colon extending to anal verge landed patient into APR: a rare finding

Jain¹,

Jain²

2018

Int Surg J

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Angiodysplasias is a kind of vascular malformation preferably involves the veins. Angiodysplasia of colon is the second most common cause of lower gastrointestinal bleeding after diverticulosis. It usually involves caecum and ascending colon. Patient may either present with complaints of fresh bleeding per rectum or with melena. It usually occurs in elderly because of age related degeneration of small blood vessel walls. The case presented here involves a male patient of 25-year age with complains of intermittent bleeding per rectum and generalized weakness from one month. After examination it was found to have vascular ectasia involving mid transverse colon, left colon and the rectum coming down to anal verge which culminated into abdominoperineal resection. Biopsy of resected segment came to be angiodysplasia with external surface of specimen showing dilation of multiple vascular channels in entire length up to anal verge. This case report shows that though angiodysplasia is more common in old age but while exploring a young patient with lower gastrointestinal tract bleeding, and congestive changes are found in left colon possibility of angiodysplasia should also be kept in mind.

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“…There are various theories proposed to explain the pathogenesis. It has been suggested that colonic angiectasia might be a result of chronic, partial, intermittent and low‐grade obstruction of the submucosal veins at the sites at which they penetrate the muscle layer of the colon, and that such mechanical compression may be induced by the wall tension of the colon [2,16]. Previous reports have also suggested intermittent submucosal venous obstruction, intermittent abnormal arterial flow, and local vascular degeneration with local hypoxaemia as potential aetiological factors [17,18].…”

Section: Discussionmentioning

confidence: 99%

“…With the widespread use of endoscopy, it is now recognized to be common. Although it may occur in any part of the gastrointestinal tract, several reports have suggested that the colon is one of the most frequent sites of occurrence [1,2]. Colonic angiectasia was first reported as a haemangioma of the sigmoid colon by Holman [3], and Marguilis et al [4] reported arteriovenous malformations diagnosed by angiography to be a cause of gastrointestinal bleeding.…”

Section: Introductionmentioning

confidence: 99%

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Clinical associations and risk factors for bleeding from colonic angiectasia: a case‐controlled study

et al. 2012

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Aim A case‐controlled study was performed to investigate the association of colonic angiectasia with other conditions and to identify risk factors for bleeding. Method Information was collected from all patients who underwent colonoscopy at our hospital between January 2008 and December 2010. Data on 90 individuals with angiectasia [58 men; median age 69 (26–92) years] were compared with those of 180 individuals without angiectasia, matched for gender and age. Results Multivariate analysis showed that occult gastrointestinal bleeding [odds ratio (OR) 2.523; 95% confidence interval (CI) 1.238–5.142], liver cirrhosis (OR 13.195; 95% CI 3.502–49.711), chronic renal failure (OR 6.796; 95% CI 1.598–28.904) and valvular heart disease (OR 6.425; 95% CI 1.028–40.165) were identified as significant predictors of the presence of colonic angiectasia. Eight patients were diagnosed with bleeding from angiectasia. Cardiovascular disease (OR 22.047; 95% CI 1.063–457.345) and multiple angiectasias (P‐value 0.0019) were identified as significant risk factors for active bleeding. Medication and a large size were not associated with an increased risk of bleeding. Conclusion The presence of colonic angiectasia was associated with valvular heart disease, liver cirrhosis and chronic renal failure. Valvular heart disease and multiple lesions increased the risk of bleeding.

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Chronic Gastrointestinal Bleeding

Cited by 5 publications

References 310 publications

Angiodysplasia of Left Colon Extending to Anal Verge Landed Patient into Apr: A Rare Diagnosis

Angiodysplasia of Left Colon Extending to Anal Verge Landed Patient into Apr: A Rare Diagnosis

Angiodysplasia of left colon extending to anal verge landed patient into APR: a rare finding

Clinical associations and risk factors for bleeding from colonic angiectasia: a case‐controlled study

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