Chronic high-caloric diet accentuates age-induced sleep alterations in mice

Panagiotou, Maria; Deboer, Tom

doi:10.1016/j.bbr.2019.01.017

Cited by 9 publications

(3 citation statements)

References 58 publications

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“…As adolescents become older, academic pressures increase, leading to sleep loss and later The dependent variable was pubertal timing: on-time = 0; early pubertal timing = 1 a Bedtimes as a continuous variable bedtime. Furthermore, overweight or obesity is a risk factor for many sleep breathing diseases [40,41], which is consistent with our findings. The research also suggested that later bedtimes were predominant in only children.…”

Section: Discussionsupporting

confidence: 93%

The association between sleep duration, bedtimes, and early pubertal timing among Chinese adolescents: a cross-sectional study

Hua

Wang

Yang

et al. 2020

Environ Health Prev Med

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Background and objective Early pubertal timing is associated with sleep among Western adolescents, but little is known about this association in Chinese adolescents, especially with regard to the association between bedtimes and early pubertal timing. This paper aimed to identify the association between sleep duration, bedtimes, and early pubertal timing in Chinese adolescents. Methods An anonymous cross-sectional survey was conducted among primary and junior middle students (grades 3 to 9) from QiJiang District, ChongQing, China. Participants were recruited by applying stratified cluster sampling. Pubertal timing, sleep duration, and bedtimes were assessed using the Pubertal Development Scale and a self-designed sleep questionnaire. We utilized multivariable logistic linear regression (MLLR) to test the association between sleep duration, bedtimes, and pubertal timing. Results A total of 5461 adolescents were evaluated, with mean age and BMI values of 11.41 ± 2.05 and 18.03 ± 3.03, respectively, of whom 1257 (23.02%) were in early pubertal timing. In MLLR controlling for age, BMI, family economic status, and other covariates, sufficient sleep (b = − 0.214, P = 0.032, OR = 0.808, 95% CI 0.664–0.982) was negatively related to early pubertal timing, and later bedtime (b = 0.195, P < 0.001, OR = 1.215, 95% CI 1.104–1.338) was positively associated with early pubertal timing. Conclusion Students with early pubertal timing had less sleep duration and later bedtimes, which may be the result of increased stress caused by physical and psychological changes. Therefore, more attention should be paid to pubertal health education for adolescents during puberty. Further longitudinal studies are needed to confirm the causality between sleep and early pubertal timing in Chinese adolescents.

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Section: Discussionsupporting

confidence: 93%

The association between sleep duration, bedtimes, and early pubertal timing among Chinese adolescents: a cross-sectional study

Hua

Wang

Yang

et al. 2020

Environ Health Prev Med

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“…Spectral analysis was performed using fast Fourier transform (FFT; 0.1–25 Hz, 0.1 Hz resolution); the relative power density spectra of waking and REM sleep in caffeine and saline day (CT0-CT6) were analyzed. The peak frequency of waking (theta range) and REM sleep was determined in hourly values in the same 6 h. Sleep–wake state episodes were determined with an algorithm described previously [ 67 ]. Episodes of each vigilance state were partitioned into a maximum of ten bins with the exponentially increased duration from 10 s to >2560 s. All PLH neuronal activity and EEG power density data were standardized relative to the mean 24 h saline control injection day in NREM sleep.…”

Section: Methodsmentioning

confidence: 99%

Long-Term Effect of a Single Dose of Caffeine on Sleep, the Sleep EEG and Neuronal Activity in the Peduncular Part of the Lateral Hypothalamus under Constant Dark Conditions

Wang

Deboer

2022

Clocks & Sleep

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Background: Caffeine is a central nervous system stimulant that influences both the sleep–wake cycle and the circadian clock and is known to influence neuronal activity in the lateral hypothalamus, an important area involved in sleep–wake regulation. Light is a strong zeitgeber and it is known to interact with the effect of caffeine on the sleep–wake cycle. We therefore wanted to investigate the long-term effects of a single dose of caffeine under constant dark conditions. Methods: We performed long-term (2 days) electroencephalogram (EEG)/electromyogram recordings combined with multi-unit neuronal activity recordings in the peduncular part of the lateral hypothalamus (PLH) under constant darkness in Brown Norway rats, and investigated the effect of a single caffeine treatment (15 mg/kg) or saline control given 1 h after the onset of the endogenous rest phase. Results: After a reduction in sleep and an increase in waking and activity in the first hours after administration, also on the second recording day after caffeine administration, rapid eye movement (REM) sleep was still reduced. Analysis of the EEG showed that power density in the theta range during waking and REM sleep was increased for at least two days. Neuronal activity in PLH was also increased for two days after the treatment, particularly during non-rapid eye movement sleep. Conclusion: Surprisingly, the data reveal long-term effects of a single dose of caffeine on vigilance states, EEG, and neuronal activity in the PLH. The absence of a light–dark cycle may have enabled the expression of these long-term changes. It therefore may be that caffeine, or its metabolites, have a stronger and longer lasting influence, particularly on the expression of REM sleep, than acknowledged until now.

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“…The effects of lipid intake on sleep have primarily been studied in high fat diet obesity models, rather than isocaloric meals containing altered lipid proportions, so it is difficult to separate the effects of dietary fats from that of obesity-related behavioral changes. In mice, high fat diets have been shown to increase sleep pressure, reduce wakefulness, and fragment sleep, as supported by a significant increase in SWA during both wake and rest phases (131,132). Alterations to fatty acid metabolism also alter sleep parameters.…”

Section: High Fat Diet and Sleep Needmentioning

confidence: 99%

The interplay between macronutrients and sleep: focus on circadian and homeostatic processes

Gangitano,

Baxter,

Voronkov

et al. 2023

Front. Nutr.

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Sleep disturbances are an emerging risk factor for metabolic diseases, for which the burden is particularly worrying worldwide. The importance of sleep for metabolic health is being increasingly recognized, and not only the amount of sleep plays an important role, but also its quality. In this review, we studied the evidence in the literature on macronutrients and their influence on sleep, focusing on the mechanisms that may lay behind this interaction. In particular, we focused on the effects of macronutrients on circadian and homeostatic processes of sleep in preclinical models, and reviewed the evidence of clinical studies in humans. Given the importance of sleep for health, and the role of circadian biology in healthy sleep, it is important to understand how macronutrients regulate circadian clocks and sleep homeostasis.

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Chronic high-caloric diet accentuates age-induced sleep alterations in mice

Cited by 9 publications

References 58 publications

The association between sleep duration, bedtimes, and early pubertal timing among Chinese adolescents: a cross-sectional study

The association between sleep duration, bedtimes, and early pubertal timing among Chinese adolescents: a cross-sectional study

Long-Term Effect of a Single Dose of Caffeine on Sleep, the Sleep EEG and Neuronal Activity in the Peduncular Part of the Lateral Hypothalamus under Constant Dark Conditions

The interplay between macronutrients and sleep: focus on circadian and homeostatic processes

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