Chronic Kidney Disease: Common, Harmful and Treatable – World Kidney Day 2007

Levey, Andrew S.; Andreoli, Sharon P.; DuBose, Thomas D.; Provenzano, Robert; Collins, Allan J.

doi:10.1159/000099801

Cited by 55 publications

(29 citation statements)

References 30 publications

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“…On March 8, 2007 (the second ‘World Kidney Day’), activities have been performed throughout China. The message of the World Kidney Day is that kidney disease is common and harmful, but treatable [49]. The CSN will launch a study on the CKD epidemic in China, in order to facilitate early prevention of CKD by controlling diabetes, hypertension and hyperlipidemia, and furthermore to have patients with mild or moderate CKD treated as early as possible.…”

Section: Ckd: a Great Challenge To Chinese Nephrologistsmentioning

confidence: 99%

Epidemiology, Major Outcomes, Risk Factors, Prevention and Management of Chronic Kidney Disease in China

Xie

Chen

2007

Am J Nephrol

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Chronic kidney disease (CKD) is common in China. In residents older than 40 years in Beijing, China, 11.3% of subjects had at least one indicator of kidney damage. The primary cause of chronic renal failure in China was glomerulonephritis, which was followed by diabetic nephropathy and hypertensive nephrosclerosis. Renal failure, cardiovascular disease and infection were important complications. IgA nephropathy (IgAN) is the most common CKD in China. The prevalence of hypertension, intrarenal artery lesions and tubulointerstitial lesions in patients with IgAN at the time of renal biopsy was approximately 40, 55 and 85%, respectively. The genetic variation in Megsin confers susceptibility to IgAN in Chinese. The patients with SL/LL genotypes of the MUC20 gene, the 38AA genotype of uteroglobin and DD genotype of the angiotensin-converting enzyme gene had a higher risk of progression. Chinese prospective clinical trials showed that benazepril (BZ) conferred substantial renal benefits in patients with advanced renal insufficiency. The combined therapy with urokinase and BZ was more effective than with BZ alone in reducing proteinuria and protecting renal function in Chinese patients with severe IgAN. Lupus nephritis (LN) is a common form of secondary renal disease diagnosed by renal biopsy in China. Chinese multicenter clinical trials showed that mycophenolate mofetil or leflunomide combined with steroids was effective as induction therapy for proliferative LN.

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Section: Ckd: a Great Challenge To Chinese Nephrologistsmentioning

confidence: 99%

Epidemiology, Major Outcomes, Risk Factors, Prevention and Management of Chronic Kidney Disease in China

Xie

Chen

2007

Am J Nephrol

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“…Chronic kidney disease (CKD) is a growing public health problem that has become recognized globally as an important cause of premature morbidity and mortality 1–3 . Disparities in CKD may be related to many factors such as socioeconomic status (SES), gender, and race/ethnicity 4–6 .…”

Section: Introductionmentioning

confidence: 99%

Socioeconomic Disparities in Chronic Kidney Disease

Nicholas

Kalantar-Zadeh

Norris

2015

Advances in Chronic Kidney Disease

195

164

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Chronic kidney disease (CKD) is a national public health problem that afflicts persons of all segments of society. While racial/ethnic disparities in advanced CKD including dialysis dependent populations have been well established, the finding of differences in CKD incidence, prevalence and progression across different socioeconomic groups and racial and ethnic strata has only recently started to receive significant attention. Socioeconomics may exert both interdependent and independent effects on CKD and its complications, and may confound racial and ethnic disparities. Socioeconomic constellations influence not only access to quality care for CKD risk factors and CKD treatment, but may mediate many of the cultural and environmental determinants of health that are becoming more widely recognized as impacting complex medical disorders. In this manuscript we have reviewed the available literature pertaining to the role of socioeconomic status and economic factors in both non-dialysis dependent CKD and end-stage-renal disease. Advancing our understanding of the role of socioeconomic factors in patients with or at risk for CKD can lead to improved strategies for disease prevention and management.

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“…World Kidney Day (WKD) is an initiative of the International Society of Nephrology and International Federation of Kidney Foundations that is intended to raise awareness and increase the detection of chronic kidney disease (CKD) in the general population [1]. The message of WKD is that kidney disease is 'common', 'harmful' and 'treatable'.…”

Section: Introductionmentioning

confidence: 99%

Screening for kidney disease in children on World Kidney Day in Jalisco, Mexico

et al. 2009

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World Kidney Day (WKD) is intended to raise awareness and increase detection of chronic kidney disease (CKD), but most emphasis is placed on adults rather than children. We examined yield of screening for CKD and hypertension among poor children in Mexico. On WKD (2006, 2007), children (age < 18 years) without known CKD were invited to participate at two screening stations. We measured body mass index (BMI), blood pressure, and serum creatinine, and performed dipstick urinalysis. The Schwartz equation was used to estimate glomerular filtration rate (GFR; reduced GFR defined as < 60 ml/min per 1.73 m(2)). Proteinuria and hematuria were defined by a reading of >or= 1+ protein or blood on dipstick. Hypertension was defined by gender, age, and height-specific norms. In total, 240 children were screened (mean age 8.9 +/- 4.1 years; 44.2% male). Proteinuria and hematuria were detected in 38 (16.1%) and 41 (17.5%), respectively; 15% had BMI > 95th percentile for age. Reduced GFR was detected in four (1.7%) individuals. Systolic hypertension was more prevalent in younger children (age 0-8 years, 19.6%; age 9-13 years, 7.1%; age 14-17 years, 5.3%) suggesting a possible white-coat effect. Hematuria, proteinuria, hypertension and obesity were frequently detected among children in a community based screening program in Mexico. This form of screening might be useful in identifying children with CKD and hypertension in developing nations.

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Chronic Kidney Disease: Common, Harmful and Treatable – World Kidney Day 2007

Cited by 55 publications

References 30 publications

Epidemiology, Major Outcomes, Risk Factors, Prevention and Management of Chronic Kidney Disease in China

Epidemiology, Major Outcomes, Risk Factors, Prevention and Management of Chronic Kidney Disease in China

Socioeconomic Disparities in Chronic Kidney Disease

Screening for kidney disease in children on World Kidney Day in Jalisco, Mexico

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