Chronic Kidney Disease: Early Detection, Mechanisms, and Therapeutic Implications

Delrue, Charlotte; Speeckaert, Marijn M.

doi:10.3390/jpm13101447

Cited by 1 publication

(1 citation statement)

References 8 publications

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“…Chronic kidney disease (CKD), characterized by progressively declining kidney function and vascular complications, can ultimately lead to chronic renal failure that requires dialysis or transplantation [1]. CKD often gives rise to various neurological issues, including cerebrovascular disorders such as stroke, cognitive impairment, white matter diseases, and headaches [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Associations between Chronic Kidney Disease and Migraine Incidence: Findings from a Korean Longitudinal Big Data Study

Kwon,

Kim,

Kim

et al. 2024

JPM

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While headaches frequently occur in individuals with chronic kidney disease (CKD), there are few statistical evaluations of their connection to migraines in population-based studies. In this nationwide longitudinal follow-up study of Korean health examination data (2002–2019), a total of 15,443 participants with CKD and 61,772 matched controls were enrolled. We applied overlap-weighted Cox proportional hazard regression models to assess hazard ratios, examining the correlation between CKD and the development of migraines. After accounting for various factors, we observed a modest reduction of approximately 11% in the likelihood of migraine occurrence among CKD patients (95% confidence intervals = 0.81–0.97) during the 16-year monitoring period. Subgroup analysis revealed a significant association among specific demographic and health conditions, including individuals aged 70 or older, females, overweight individuals, nonsmokers, and those without hypertension or diabetes. Our research may indicate a potential relationship between CKD and the onset of migraines in Korean adults, suggesting a slight reduction in the probability of the occurrence of migraines among those with CKD. These findings emphasize the need for attentive follow-up and preventive management in individuals without the identified protective factors, particularly in male CKD patients under the age of 70 with hypertension.

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Section: Introductionmentioning

confidence: 99%

Associations between Chronic Kidney Disease and Migraine Incidence: Findings from a Korean Longitudinal Big Data Study

Kwon,

Kim,

Kim

et al. 2024

JPM

View full text Add to dashboard Cite

show abstract

Chronic Kidney Disease: Early Detection, Mechanisms, and Therapeutic Implications

Abstract: Chronic Kidney Disease (CKD) constitutes a global health crisis, silently affecting millions worldwide [...]

Cited by 1 publication

References 8 publications

Associations between Chronic Kidney Disease and Migraine Incidence: Findings from a Korean Longitudinal Big Data Study

Associations between Chronic Kidney Disease and Migraine Incidence: Findings from a Korean Longitudinal Big Data Study

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