Chronic kidney disease in children: The National Paediatric Hospital experience in Hanoi, Vietnam

Hương, Nguyễn Thị Quỳnh; Long, Tran Dinh; Bouissou, F; Liêm, Nguyễn Thanh; Truong, Dinh Minh; Nga, Do Kim; Chien, Tran Thi Trung; Bascands, Jean-Loup

doi:10.1111/j.1440-1797.2009.01142.x

Cited by 19 publications

(13 citation statements)

References 14 publications

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“…there was a high prevalence of glomerular diseases (68.5%), comparable to published data from developing countries like Vietnam [17] , Sudan [18] , Thailand [20] and Malaysia [24] . It has been postulated that high proportions of glomerulonephritis may be related to high prevalence of bacterial, viral and parasitic infections that commonly affect the kidneys in developing countries [14] .…”

Section: Tan Sy Et Al Ckd In Children In Bruneisupporting

confidence: 70%

Chronic kidney disease in children and adolescents in Brunei Darussalam

Tan

Lin

Han

et al. 2016

WJN

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AIM:To determine epidemiology of Bruneian paediatric chronic kidney disease (CKD) patients and factors that affect growth and progression of disease. METHODS:A cross-sectional study conducted on all children below 18 years old who were diagnosed with CKD over a ten year period (2004 to 2013). The reference population was all children (< 18 years old) suffering from CKD and attending the tertiary paediatric nephrology clinic in Brunei Darussalam. Demographic (current age, age of diagnosis, gender, ethnicity), anthropometric (weight and height), diagnosis, laboratory data (serum creatinine and haemoglobin, urinalysis) and blood pressure were extracted from the patients' clinical case notes and recorded using a data collection form. RESULTS:The study revealed a high national prevalence [736 per million child population (pmcp)] and incidence (91 pcmp) of CKD. If CKD was defined at Stage 1, 2, 3, 4 or 5, the associated prevalence figures were 736, 132, 83, 50 and 33 pmcp. Glomerulonephritis accounted for 69% of all prevalent cases, followed by congenital abnormalities of kidney and urinary tract (20%) and tubulointerstitial diseases (8%). Minimal change disease being the most common histological diagnosis. The median age of diagnosis was 4.5 years, with congenital disease patients experiencing an earlier onset of diagnosis. A large ORIGINAL ARTICLE Observational Studyproportion of patients were below the 5% percentile for height and weight. Non-glomerular diseases, adolescent and female patients were significantly associated with poor growth, but not glomerular filtration rate, age of diagnosis or steroid usage. CONCLUSION:Brunei has a high prevalence of chronic kidney disease in the paediatric population with glomerulonephritis being the most common disease.

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Section: Tan Sy Et Al Ckd In Children In Bruneisupporting

confidence: 70%

Chronic kidney disease in children and adolescents in Brunei Darussalam

Tan

Lin

Han

et al. 2016

WJN

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“…An incidence of 11 pmarp and a prevalence of 51 pmarp have been reported in Jordanian children [16]. Two reports from Vietnam have suggested an annual incidence of hospitalization for CKD of around 5 pmarp, and most of the patients had already reached ESRD [19, 20]. …”

Section: Demographics Of Ckdmentioning

confidence: 99%

Epidemiology of chronic kidney disease in children

et al. 2011

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In the past 30 years there have been major improvements in the care of children with chronic kidney disease (CKD). However, most of the available epidemiological data stem from end-stage renal disease (ESRD) registries and information on the earlier stages of pediatric CKD is still limited. The median reported incidence of renal replacement therapy (RRT) in children aged 0–19 years across the world in 2008 was 9 per million of the age-related population (4–18 years). The prevalence of RRT in 2008 ranged from 18 to 100 per million of the age-related population. Congenital disorders, including congenital anomalies of the kidney and urinary tract (CAKUT) and hereditary nephropathies, are responsible for about two thirds of all cases of CKD in developed countries, while acquired causes predominate in developing countries. Children with congenital disorders experience a slower progression of CKD than those with glomerulonephritis, resulting in a lower proportion of CAKUT in the ESRD population compared with less advanced stages of CKD. Most children with ESRD start on dialysis and then receive a transplant. While the survival rate of children with ERSD has improved, it remains about 30 times lower than that of healthy peers. Children now mainly die of cardiovascular causes and infection rather than from renal failure.Electronic supplementary materialThe online version of this article (doi:10.1007/s00467-011-1939-1) contains supplementary material, which is available to authorized users

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“…In our study only 7.8% of parents refused treatment. In study of Gulati in 1999, in India[13] 40% and in Vietnam[10] 50% of parents refused from further therapy because of financial problems.…”

Section: Discussionmentioning

confidence: 99%

“…[5] While in a 5-year study in Sudan, only 3.9% of ESRD children underwent transplantation[9] and in Vietnam more than 70% of pediatric ESRD patients did not benefit from RRT due to limited facilities for RRT in children. [1011]…”

Section: Introductionmentioning

confidence: 99%

Management and outcome of children with end-stage renal disease in northwest Iran

Mortazavi

Maleki

2012

Indian J Nephrol

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Outcome of end-stage renal disease (ESRD) in children has considerably improved since the development of dialysis and kidney transplantation. This study was conducted to evaluate the management and outcome of ESRD children in a referral pediatric center in northwest Iran. A cross-sectional study of medical records of ESRD children (glomerular filtration rate less than 15 ml/min/1.73 m2) younger than 16 years who were admitted in Children's Hospital of Tabriz between October 1999 and October 2009 was performed. Ninety-four children with ESRD including 51 boys (54.3%) and 43 girls (45.7%) with a mean age of 7.9 ± 3.49 years were studied. Parents of nine patients (7.8%) refused treatment. Eighty patients underwent renal replacement therapy (RRT) and were followed for a mean period of 4.86 ± 2.77 years. Initial modality of RRT was hemodialysis in 81.25%, continuous ambulatory peritoneal dialysis in 16.25%, and preemptive kidney transplantation in 2.5%. Thirty-two patients (34%) underwent renal transplantation. The mean duration of staying on dialysis before transplantation was 12.4 ± 11 months. Twenty-nine of kidney donors (90.6%) were living unrelated donors. The 1-and 3-year graft survival rates were 81.2% and 68.8% and the 1- and 3-year patient survival rates were 96.9% and 93.8%, respectively. Thirty-one patients died (33%). The mortality of girls was significantly higher than boys (P=0.04). There was a significant negative correlation between age and mortality (P=0.01). Heart failure and infections were the most common cause of death. This study showed that ESRD children in our area have a poor outcome in comparison with developed countries.

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Chronic kidney disease in children: The National Paediatric Hospital experience in Hanoi, Vietnam

Abstract: Late referral, and limited facilities for renal replacement therapy explain the poor outcome in this study. We need a program to delineate the burden of chronic kidney disease and improve primary health care for health promotion and prevention of paediatric chronic kidney disease.

Cited by 19 publications

References 14 publications

Chronic kidney disease in children and adolescents in Brunei Darussalam

Chronic kidney disease in children and adolescents in Brunei Darussalam

Epidemiology of chronic kidney disease in children

Management and outcome of children with end-stage renal disease in northwest Iran

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