Chronic kidney disease in children: the global perspective

Warady, Bradley A.; Chadha, Vimal

doi:10.1007/s00467-006-0410-1

Cited by 515 publications

(392 citation statements)

References 53 publications

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“…These charges are beyond the means of most of the population considering the per capita GDP of <$10 000 (Table 1). Paucity of facilities in the public sector, high costs in the private and inaccessibility of centers render 75-85% of the children disfranchised from RRT (20,21,25). In fact 35% refuse RRT in India due to high costs (8) and 8% in Iran (26).…”

Section: Access To Renal Replacement Therapymentioning

confidence: 99%

Pediatric Kidney Transplantation in the Developing World: Challenges and Solutions

Rizvi

Sultan

Zafar

et al. 2013

American Journal of Transplantation

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The prevalence of pediatric RRT and transplantation are low in developing countries, 6-12 and <1 to 5 per million child population (pmcp), respectively. This is due to low GDP/capita of <$10 000, government expenditure on health of <2.6-9% of GDP and paucity of facilities. The reported incidence of pediatric CKD and ESRD is <1.0-8 and 3.4-35 pmcp, respectively. RRT and transplantation are offered mostly in private centers in cities where HD costs $20-100/session and transplants $10 000-20 000. High costs and long distance to centers results in treatment refusal in up to 35% of the cases. In this backdrop 75-85% of children with ESRD are disfranchised from RRT and transplantation. Our center initiated an integrated dialysis-transplant program funded by a community-government partnership where RRT and transplantation was provided ''free of cost'' with life long follow-up and medication. Access to free RRT at doorsteps and transplantation lead to societal acceptance of transplantation as the therapy of choice for ESRD. This enabled us to perform 475 pediatric transplants in 25 years with 1-and 5-year graft survival of 96% and 81%, respectively. Our model shows that pediatric transplantation is possible in developing countries when freely available and accessible to all who need it in the public sector.

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Section: Access To Renal Replacement Therapymentioning

confidence: 99%

Pediatric Kidney Transplantation in the Developing World: Challenges and Solutions

Rizvi

Sultan

Zafar

et al. 2013

American Journal of Transplantation

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“…[1][2][3][4] Además, la IRC infantil -en su mayoría de tipo congénito-y las complicaciones de muchas enfermedades no renales que afectan los riñones de manera secundaria, no solamente producen morbimortalidad considerable durante la niñez, sino que también llevan a afecciones médicas más allá de este período. De hecho, muchas muertes infantiles causadas por una larga lista de enfermedades transmisibles están inextricablemente relacionadas con el compromiso renal.…”

Section: Introductionunclassified

“…La prevalencia de la IRC infantil es rara: se ha notificado con una variación de 15 a 74,7 cada millón de niños. 3 La causa de dicha variación probablemente sea que los datos sobre la IRC están influenciados por factores regionales y culturales, además de la metodología empleada para generarlos. Recientemente, la Organización Mundial de la Salud (OMS) incorporó las nefropatías y las uropatías a la información sobre mortalidad registrada a nivel mundial, la cual debería considerarse, con el tiempo, como una valiosa fuente de información; sin embargo, la OMS no publica dicha información por grupo etario.…”

Section: Introductionunclassified

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Día Mundial del Riñón 2016. Prevención del legado de la nefropatía, con enfoque en la niñez

2016

Arch Argent Pediat

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“…systemic lupus erythematous), vascular inflammation, bacterial and viral infection, tubulointerstitial renal disorders (e.g. toxic influence of drugs), some genetic disorders (polycystic kidney, Alport syndrome) [6].…”

mentioning

confidence: 99%

Oral Health in Chronic Kidney Disease Patients: A Literature Review

Rabiega¹,

Eliasz²,

Pawlaczyk³

2016

Dent. Med. Probl.

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Chronic kidney disease (CKD) is a broad term used to describe progressive structural and functional kidney disorders that may be accompanied by a decrease in the glomerular filtration rate (GFR), and that have lasted for at least 3 months [1]. The diagnosis of CKD is also made if GFR values are below 60 mL/min/1.73 m 2 for a minimum of 3 months, independently of the presence of kidney damage markers [2,3]. There are several symptoms that can indicate CKD in patients, e.g. abnormalities visible in diagnostic imaging procedures, in blood and urine tests (e.g. proteinuria, abnormal urine sediment) or blood morphology. GFR is, however, the most important factor when it comes to the physiopathology of chronic kidney disease. Nowadays, CKD is classified into five stages, according to the value of this index: stage 1 (GFR > 90 mL/ /min/1.73 m 2 ), stage 2 (60-89 mL/min/1.73 m 2 ), stage 3 (30-59 mL/min/1.73 m 2 ), stage 4 (15-29 mL/min/1.73 m 2 ) and stage 5 (GFR < 15 mL/ /min/1.73 m 2 ). Stage 3 can be further divided into 3A (45-59 mL/min/1.73 m 2 ) and 3B (30-44 mL/ /min/1.73 m 2 ). Stage 5, the most advanced and dangerous one, is also described as "end-stage renal failure" (ESRF), and constitutes an indica-REVIEWS

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Chronic kidney disease in children: the global perspective

Cited by 515 publications

References 53 publications

Pediatric Kidney Transplantation in the Developing World: Challenges and Solutions

Pediatric Kidney Transplantation in the Developing World: Challenges and Solutions

Día Mundial del Riñón 2016. Prevención del legado de la nefropatía, con enfoque en la niñez

Oral Health in Chronic Kidney Disease Patients: A Literature Review

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