Chronic myelomonocytic leukemia (CMML) associated with symptomatic pericardial effusion.

Impact of Mutational Status and Prognostic Factors on Survival in Chronic Myelomonocytic Leukemia With Systemic Inflammation and Autoimmune Disorders

“…Previous studies reported a prevalence of ITP in 29% of CMML with SIAD, whereas inflammatory skin diseases, mostly neutrophilic dermatoses, and inflammatory arthritis were reported up to 15% 8–10 . Cases of pericarditis associated with CMML without pericardial monocyte infiltration have been described 11 . Some cohorts reported a prevalence of vasculitis in up to half of CMML patients with SIAD, mostly PAN 10,12 .…”

“…[8][9][10] Cases of pericarditis associated with CMML without pericardial monocyte infiltration have been described. 11 Some cohorts reported a prevalence of vasculitis in up to half of CMML patients with SIAD, mostly PAN. 10,12 Discerning causality or coincidence the association of SIAD and CMML is difficult, notably when SIAD precedes CMML by several years.…”

Chronic myelomonocytic leukemia primarily presenting as life‐threatening pericardial effusion, Eldoret, Kenya: A case report

“…Pericardial effusion as an initial presentation of CMML is rare and has been reported in few case reports in literature, 7,[15][16][17] reflecting the rarity of this presentation. Not detected early, pericardial effusion could lead to cardiac tamponade or acute HF as in our case.…”