Chronic pain patients' perspectives of medical cannabis

Piper, Brian J.; Beals, Monica; Abess, Alexander T.; Nichols, Stephanie D.; Martin, Maurice; Cobb, Catherine M.; DeKeuster, Rebecca M.

doi:10.1097/j.pain.0000000000000899

Cited by 92 publications

(100 citation statements)

References 31 publications

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“…Nine studies were qualitative and data were collected by interview [56,58,63,74,77,84,91,93,96]. Three studies used closed-ended questions with free space for comments or open-ended questions [60,65,98]. Thirty-four studies used quantitative methods.…”

Section: Characteristics Of the Included Studiesmentioning

confidence: 99%

“…Two studies were supported by non-governmental organizations [51,87]. Five studies received mixed funding from research grants, non-governmental organizations, dispensaries or private foundations [57, 64,65,68,82,94]. All the ve studies that were supported by mixed funding also had received funding from commercial enterprises with a speci c focus towards cannabis, or from cannabis interest or patients groups [51,57,64,68,87,94].…”

Section: Fundingmentioning

confidence: 99%

“…Perceived positive and negative effects MC smoking was described by the participants as enjoyable, easy to titrate, and procuring immediate pain relief [34,65,74,77,78,84]; however, respiratory side effects and bad smell and taste were perceived as negative effects of cannabis smoking [65,74,78,96] (Table 2). Edible MC products were considered healthier, tasty when cooked in a recipe, and with long-lasting pain relief effects [34,63] [71] to 63% of participants [75].…”

Section: Patterns Of MC Usementioning

confidence: 99%

“…Obstacles to the medical use of cannabis have been reported at several levels (Supplemental Table S2), including stigmatization from others [65,77], fear of discrimination [73]…”

Section: Reported Barriers To the Medical Use Of Cannabismentioning

confidence: 99%

“…The conditions permitting to be registered as a MC user as well as access to MC vary between states, countries and over time. For example, MC can be obtained from pharmacies in the Netherlands [83,85,89], from special dispensaries in some cities of the US [36,54,57,61,65,70,72], and since 2013 from registered producers in Canada [75,78,80]. The included studies, therefore, recruited participants from different sources: dispensaries, registration clinics, or through online advertisement.…”

Section: Strengths and Limitations Of The Reviewmentioning

confidence: 99%

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Cannabis against chronic muskuloskeletal pain: A scoping review on users and their perceptions

Furrer

Kröger

Marcotte

et al. 2020

Preprint

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Abstract Background Chronic musculoskeletal pain (CMP) may lead to reduced physical function and is the most common cause of chronic non cancer pain. Currently, the pharmacotherapeutic options against CMP are limited and mainly consist of pain management with gabapentinoids or opioids, which carry major adverse effects. Although the effectiveness of medical cannabis (MC) for CMP still lacks solid evidence, several patients suffering from it are exploring this therapeutic option.Objectives Little is known about MC users suffering from CMP. We aimed to increase this knowledge, useful for health care professionals and policy makers considering this treatment, as well as for researchers planning rigorous randomized clinical trials on the effectiveness of MC.Methods We conducted a scoping literature review, according to the methods developed by Arksey and O’Malley, to describe the views and perceptions of patients who had consumed MC to relieve chronic CMP and other non-cancer pain, as well as their demographic characteristics, patterns of MC use, and perceived positive and negative effects.Conclusion Our review shows that MC users are frequently young or middle-aged men, and that the preferred form of use was smoking. Participants of the included studies reported that MC use was helpful in reducing CMP and other chronic non-cancer pain with only minor adverse effects; in addition, they reported improved psychological well-being. Discussion The information from the included studies has several methodological limitations and is exploratory. MC use might, from the perspective of persistent users suffering from CMP and other chronic non-cancer pain, produce more benefits than harms. However, specific results for CMP are very scarce.

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Section: Characteristics Of the Included Studiesmentioning

confidence: 99%

Section: Fundingmentioning

confidence: 99%

Section: Patterns Of MC Usementioning

confidence: 99%

“…Obstacles to the medical use of cannabis have been reported at several levels (Supplemental Table S2), including stigmatization from others [65,77], fear of discrimination [73]…”

Section: Reported Barriers To the Medical Use Of Cannabismentioning

confidence: 99%

Section: Strengths and Limitations Of The Reviewmentioning

confidence: 99%

See 3 more Smart Citations

Cannabis against chronic muskuloskeletal pain: A scoping review on users and their perceptions

Furrer

Kröger

Marcotte

et al. 2020

Preprint

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Medical cannabis: A forward vision for the clinician

Fitzcharles

Eisenberg

2018

European Journal of Pain

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Obesity aggravates the role of C‐reactive protein on knee pain: A cross‐sectional analysis with NHANES data

Luo,

Li,

Huang

et al. 2024

Immunity Inflam & Disease

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ObjectiveTo examine the relationship between C‐reactive protein (CRP) and knee pain, and further explore whether this association is mediated by obesity.MethodsThe population was derived from 1999 to 2004 National Health and Nutrition Examination Survey. Logistic regression was used to analyze the relationship between CRP and knee pain in three different models, and the linear trend was analyzed. A restricted cubic spline model to assess the nonlinear dose−response relationship between CRP and knee pain. Mediation analyses were used to assess the potential mediating role of obesity. Subgroup analyses and sensitivity analyses were performed to ensure robustness.ResultsCompared with adults with lower CRP (first quartile), those with higher CRP had higher risks of knee pain (odds ratio 1.39, 95% confidence interval 1.12−1.72 in third quartile; 1.56, 1.25−1.95 in fourth quartile) after adjusting for covariates (except body mass index [BMI]), and the proportion mediated by BMI was 76.10% (p < .001). BMI and CRP were linear dose−response correlated with knee pain. The odds ratio for those with obesity compared with normal to knee pain was 2.27 (1.42−3.65) in the first quartile of CRP, 1.99 (1.38−2.86) in the second, 2.15 (1.38−3.33) in the third, and 2.92 (1.72−4.97) in the fourth.ConclusionObesity mediated the systemic inflammation results in knee pain in US adults. Moreover, higher BMI was associated with higher knee pain risk in different degree CRP subgroups, supporting an important role of weight loss in reducing knee pain caused by systemic inflammation.

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Chronic pain patients' perspectives of medical cannabis

Abstract: Summary Medical cannabis patients, including two-thirds with chronic-pain, report health benefits including improved pain management and sleep. Pharmacoeconomic factors were the greatest limitation of medical cannabis.

Cited by 92 publications

References 31 publications

Cannabis against chronic muskuloskeletal pain: A scoping review on users and their perceptions

Cannabis against chronic muskuloskeletal pain: A scoping review on users and their perceptions

Medical cannabis: A forward vision for the clinician

Obesity aggravates the role of C‐reactive protein on knee pain: A cross‐sectional analysis with NHANES data

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