Chronic pancreatitis with secondary diabetes mellitus treated by use of insulin in an adult California sea lion

Meegan, Jenny; Sidor, Inga; Steiner, Jörg M.; Sarran, Delphine; Dunn, J. Lawrence

doi:10.2460/javma.232.11.1707

Cited by 7 publications

(6 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1 Formation of fructosamine is proportional to the degree and duration of hyperglycemia within the patient. [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] It has also been shown to be a useful marker for differentiating nondiabetic causes of glucosuria. [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] It has also been shown to be a useful marker for differentiating nondiabetic causes of glucosuria.…”

mentioning

confidence: 99%

Reference Point: Exploring fructosamine beyond diabetes mellitus

Pattullo

Kidney²

2014

javma

View full text Add to dashboard Cite

mentioning

confidence: 99%

Reference Point: Exploring fructosamine beyond diabetes mellitus

Pattullo

Kidney²

2014

javma

View full text Add to dashboard Cite

“…Fibrosis of islets of Langerhans and chronic pancreatitis was identified in Procavia capensis (rock hyrax) and California sea lion, describing another type such as secondary DM [ 60 , 61 ]. Panthera onca , African spotted leopard, and even their progeny developed DM in confined conditions [ 62 , 63 ].…”

Section: Dm In Wild Animalsmentioning

confidence: 99%

Comparative occurrence of diabetes in canine, feline, and few wild animals and their association with pancreatic diseases and ketoacidosis with therapeutic approach

Niaz¹,

Maqbool²,

Khan³

et al. 2018

Vet World

View full text Add to dashboard Cite

Diabetes mellitus (DM) is a chronic metabolic disorder in which blood glucose level raises that can result in severe complications. However, the incidence increased mostly by obesity, pregnancy, persistent corpus luteum, and diestrus phase in humans and animals. This review has focused on addressing the possible understanding and pathogenesis of spontaneous DM in canine, feline, and few wild animals. Furthermore, pancreatic associated disorders, diabetic ketoacidosis, hormonal and drug interaction with diabetes, and herbal remedies associated with DM are elucidated. Bibliographic search for the present review was done using PubMed, Scopus, and Google Scholar for articles on concurrent DM in small and wild animals. Persistent corpus luteal and pseudopregnancy in female dogs generate gestational DM (GDM). GDM can also be caused by extensive use of drugs/hormones such as glucocorticosteroids. Although many similarities are present between diabetic cats and diabetic humans which present islet amyloidosis, there was a progressive loss of β- and α-cells and the normal number of δ-cells. The most prominent similarity is the occurrence of islet amyloidosis in all cases of diabetic cat and over 90% of human non-insulin dependent DM Type-2. Acute pancreatic necrosis (APN) occurs due to predisposing factors such as insulin antagonism, insulin resistance, alteration in glucose tolerance, obesity, hyperadrenocorticism, and persistent usage of glucocorticoids, as these play a vital role in the progression of APN. To manage such conditions, it is important to deal with the etiological agent, risk factors, diagnosis of diabetes, and hormonal and drug interaction along with its termination with suitable therapy (herbal) protocols. It should be noted that the protocols used for the diagnosis and treatment of human DM are not appropriate for animals. Further investigations regarding diabetic conditions of pets and wild animals are required, which will benefit the health status of all animals health worldwide.

show abstract

“…Secondary diabetes mellitus was also described in rock hyraxes (Procavia capensis) diagnosed with pancreatic islet fibrosis [150] and in California sea lion due to chronic pancreatitis [151].…”

Section: Diabetes Mellitus In Wildlifementioning

confidence: 99%

Spontaneous Diabetes Mellitus in Animals

Ciobotaru¹

2013

Diabetes Mellitus - Insights and Perspectives

View full text Add to dashboard Cite

[23][24][25][26]. Young individuals are constantly affected, the age ranging between 6 months and 5 years of age. Although there is no evidence of sex predilection, most of the data report cases of diabetes in females. Mild weight loss to severe emaciation, polyuria, polydipsia, dehydration, hyperglycemia, glucosuria and kenonuria are the most important clinical signs described. Previous studies mention diagnostic tests used in cattle: glucose tolerance test and measurements of serum fructosamine to prove that the most important signs of diabetes (hyperglycemia, glucosuria and kenonuria) have been induced by insulin deficiency. The results of these tests proved that the glucose disappearance rate and half time were longer than in normal control cows. Elevated values of serum fructosamine were also observed [22,25].

show abstract

Chronic pancreatitis with secondary diabetes mellitus treated by use of insulin in an adult California sea lion

Abstract: Diabetes mellitus can occur secondary to chronic pancreatitis in California sea lions and insulin therapy should be considered.

Cited by 7 publications

References 36 publications

Reference Point: Exploring fructosamine beyond diabetes mellitus

Reference Point: Exploring fructosamine beyond diabetes mellitus

Comparative occurrence of diabetes in canine, feline, and few wild animals and their association with pancreatic diseases and ketoacidosis with therapeutic approach

Spontaneous Diabetes Mellitus in Animals

Contact Info

Product

Resources

About