Chronic pelvic pain and rectal prolapse invite consideration of enterocele

Abstract

Aim Data on the pathogenesis and symptoms of enterocele are limited. The objectives of this study were to determine the clinical phenotype of patients with enterocele, to highlight the main functional and/or anatomical associations and to improve the accuracy of the preoperative assessment of pelvic floor disorders. Method A total of 588 patients who were referred to a tertiary unit for an anorectal complaint completed a self‐administered questionnaire and underwent physical examination, anorectal manometry and defaecography. Using defaecography, enterocele was defined as a radiological hernia of the small bowel into an enlarged rectovaginal space. One hundred and thirty‐five patients with enterocele were age‐ and gender‐matched with 270 patients without enterocele. Factors associated with enterocele were assessed using univariate and multivariate analysis models. Results Patients with enterocele were less frequently obese than patients without enterocele (8/135 vs 36/270; P = 0.02) and more frequently had a past history of pelvic surgery (51/135 vs 75/270; P = 0.04). They complained more frequently of pelvic pain on bearing down (29/135 vs 24/270; P = 0.003), anal procidentia (37/135 vs 46/270; P = 0.01) and more frequently had irritable bowel syndrome (83/135 vs 131/270; P = 0.01) and severe constipation according to the Kess score (104/135 vs 182/270; P = 0.04). Anorectal function was comparable between the two groups. Patients with enterocele had more frequent rectoceles and overt rectal prolapses than patients without enterocele. Conclusions Enterocele should be investigated in patients with chronic pelvic pain, overt rectal prolapse and/or a past history of pelvic surgery.

The Causal Association of Irritable Bowel Syndrome with Multiple Disease Outcomes: A Phenome-Wide Mendelian Randomization Study

“…IBS and hernia have similar symptoms, such as abdominal pain, constipation, and diarrhea, but few studies have focused on the association between these two diseases. One study focused on 558 patients with small bowel hernia and observed that IBS was more common in these patients than in those without enterocele [32]. Although the pathogenesis of IBS and diverticular disease remains incompletely understood, substantial overlap or coexistence of these two diseases has been observed.…”