Chronic Primary Pain of the Spine: an Integrative Perspective Part 2

Williamson, Timothy J; Bolles, Chandler L.; Hedges, Nicholas A.; Kettner, Norman W.

doi:10.1007/s42399-021-00779-6

Cited by 3 publications

(3 citation statements)

References 127 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, whether there are differences in neurobiological mechanisms between different sites of pain remains to be further investigated. Overall, our findings support the positive significance of psychotherapy in alleviating pain and advocate for creating greater self-efficacy and empowerment in patients [42].…”

Section: Discussionsupporting

confidence: 74%

Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study

Yao

Zhang

et al. 2023

J Headache Pain

View full text Add to dashboard Cite

Background The close relationship between pain and mental health problems is well-known, and psychological intervention can provide an effective alternative to medication-based pain relief. However, previous studies on the connection between pain and psychological problems, the findings thus far have been inconclusive, limiting the potential for translating psychological interventions into clinical practice. To complement the gap, this study utilized genetic data and Mendelian randomization (MR) to examine the potential relationship between pain in different parts and common mental disorders. Methods Based on the instrumental variables selected from the Genome-wide association study summary statistics of localized pain and mental disorders, we conducted bidirectional two-sample MR analyses to infer bidirectional causal associations between pain and mental disorders. The inverse-variance weighted MR method and MR-Egger were used as the primary statistical method according to the horizontal pleiotropy and heterogeneity level. We reported the odds ratio to infer the causal effect between pain and mental disorders. F statistic was calculated to measure the statistical efficacy of the analyses. Results Insomnia is causally related to the genetic susceptibility of multisite pain including head (OR = 1.09, 95% CI: 1.06–1.12), neck/shoulder (OR = 1.12, 95% CI: 1.07–1.16), back (OR = 1.12, 95% CI: 1.07–1.18) and hip (OR = 1.08, 95% CI: 1.05–1.10). Reversely, headache (OR = 1.14, 95% CI: 1.05–1.24), neck/shoulder pain (OR = 1.95, 95% CI: 1.03–3.68), back pain (OR = 1.40, 95% CI: 1.22–1.60), and hip pain (OR = 2.29, 95% CI: 1.18–4.45) promote the genetic liability of insomnia. Depression is strongly associated with the predisposition of multisite pain including headache (OR = 1.28, 95% CI: 1.08–1.52), neck/shoulder pain (OR = 1.32, 95% CI: 1.16–1.50), back pain (OR = 1.35, 95% CI: 1.10–1.66) and stomach/abdominal pain (OR = 1.14, 95% CI: 1.05–1.25), while headache (OR = 1.06, 95% CI: 1.03–1.08), neck/shoulder (OR = 1.09, 95% CI: 1.01–1.17), back (OR = 1.08, 95% CI: 1.03–1.14), and stomach/abdominal pain (OR = 1.19, 95% CI: 1.11–1.26) are predisposing factors for depression. Additionally, insomnia is associated with the predisposition of facial, stomach/abdominal, and knee pain, anxiety was associated with the predisposition of neck/shoulder and back pain, while the susceptibilities of hip and facial pain are influenced by depression, but these associations were unidirectional. Conclusions Our results enhance the understanding of the complex interplay between pain and mental health and highlight the importance of a holistic approach to pain management that addresses both physical and psychological factors.

show abstract

Section: Discussionsupporting

confidence: 74%

Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study

Yao

Zhang

et al. 2023

J Headache Pain

View full text Add to dashboard Cite

show abstract

“…This aligns with the growing body of evidence that underscores the probable effectiveness of physiotherapy in migraine management [ 15 , 25 , 26 ]. Physiotherapy emerges as a potential integrative tool in the treatment of migraine, with techniques such as manual therapy, which was the most recalled in our study, demonstrating to alleviate migraine symptoms, possibly addressing musculoskeletal dysfunctions that can trigger or exacerbate headaches, including those stemming from cervical pain [ 26 – 28 ]. Patients’ expectations from physiotherapy, as revealed in our study, were predominantly centered on tangible outcomes: a reduction in the number and intensity of migraine attacks, highlighting the urgent need for relief among migraine sufferers and reinforcing the potential role of physiotherapy in meeting these expectations.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, the physiotherapeutic approach can also aim to improve posture and neck mechanics, which can be additional contributing factors to the chronicization of pain in individuals with migraines. It is essential to consider neck pain not only as a symptom but also as a potential causal factor in migraine pathophysiology, which can be effectively managed through targeted physiotherapeutic interventions [ 26 – 28 ].…”

Section: Discussionmentioning

confidence: 99%

Is physiotherapy in migraines known to sufferers? A cross-sectional study

Tedeschi,

Pillastrini,

Pierangeli

et al. 2023

Neurol Sci

View full text Add to dashboard Cite

Background Migraine, a prevalent neurological condition, often impairs daily functioning and quality of life. While medications are the primary treatment, the potential of physiotherapy as an integrative approach remains underexplored. The aim of the study was to explore the awareness and experience of migraine patients regarding physiotherapy as a complementary treatment. Methods A comprehensive survey was conducted on 200 migraine patients. Data collected included demographics, diagnosis, Migraine Disability Assessment Score Questionnaire (MIDAS) scores, and perceptions and experiences related to physiotherapy. Results The average age of participants was 47.7 ± 13.2 years, with a predominance of females, 149 out of 200 (74.5%). The mean MIDAS score was 36.7 ± 45.3, indicating a significant impact on daily life. While 39 out of 200 (19.5%) had undergone physiotherapy for their headache, 161 out of 200 (80.5%) had not. Of those who had, 22 out of 39 (56.4%) reported benefits, including reduced attack intensity and frequency. Interestingly, 145 out of 161 (90.1%) expressed interest in physiotherapy, with many expecting it to reduce attack intensity, 57 out of 200 (28.5%) and frequency, 77 out of 200 (38.5%). Conclusions The study highlights the substantial burden of migraines and the potential of physiotherapy as an adjunctive treatment. Increasing awareness and accessibility to physiotherapy could offer migraine patients a more holistic treatment approach; however, randomized controlled trials are mandatory in order to confirm its efficacy.

show abstract

Evaluation of chiropractic students’ knowledge and attitudes following pain interventions: A randomized educational trial at 2 institutions

Miller,

Boylan,

Mullen

et al. 2024

Journal of Chiropractic Education

View full text Add to dashboard Cite

Objective To examine chiropractic students’ attitudes regarding knowledge of pain neuroscience, chronic pain, and patient-centered care before and after educational interventions. Secondarily, this study aimed to compare measures of these skills between cohorts at different timepoints throughout training programs. Methods Using stratified randomization, 281 Year 3 chiropractic students at 2 institutions were allocated into 1 of 3 educational interventions and served as active-control comparison groups: pain neuroscience education, chronic pain education, or patient-centered care. Participants completed validated surveys regarding their experience with the education interventions immediately pre- and post-lecture and 12 weeks after completion. For further comparison, surveys were also completed by 160 Year 1 students and 118 Year 2 students at 1 of the institutions. Independent sample t tests and 1-way analysis of variance were used for data analysis. Results All Year 3 lecture groups showed immediate improvements (pain neuroscience education: 3.99 + 3.09/100, p = .18 [95% CI: 10.10 to −1.77]; chronic pain education: 0.42 + 0.74/7, p = .02 [95% CI: 0.72 to 0.07]; patient-centered care: 0.25 + 0.12/6, p = .05 [95% CI: 0.12–0.51]), but these were not sustained at the 12-week follow-up (pain neuroscience education: −6.25 + 4.36/100, p = .15 [95% CI: 14.93 to −2.42]; chronic pain education: 0.33 + 0.16/7, p = .19 [95% CI, 0.66 to 0.01]; patient-centered care: 0.13 + 0.13/6, p = .30 [95% CI: 0.41 to −0.13]). Compared to active controls, only the patient-centered care group showed an immediate statistically significant difference. Conclusions While this study found that immediate improvement in targeted competencies is possible with focused interventions, they were not sustained long term.

show abstract

Chronic Primary Pain of the Spine: an Integrative Perspective Part 2

Cited by 3 publications

References 127 publications

Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study

Exploring the bidirectional relationship between pain and mental disorders: a comprehensive Mendelian randomization study

Is physiotherapy in migraines known to sufferers? A cross-sectional study

Evaluation of chiropractic students’ knowledge and attitudes following pain interventions: A randomized educational trial at 2 institutions

Contact Info

Product

Resources

About