Chronic Pyelonephritis

Brod, J

doi:10.1016/s0140-6736(56)91798-6

Cited by 83 publications

(20 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Fig. 6, (Loopuyt, 1946;Brod, 1956;Kass, 1956; MacDonald, Levitin, Mallory, and Kass, 1957; Jackson, Poirier, and Kleeman, Hewitt, and Guze, 1960). The present unsatisfactory diagnostic position would be much improved by widespread screening of patients by methods which are simple and reasonably accurate.…”

Section: Results and Interpretationmentioning

confidence: 97%

“…It is suggested that a quantitative bacterial count should replace non-quantitative culture methods when urinary infection is suspected and that the quantitative white cell count should be performed as a routine part of the initial clinical and laboratory assessment of all patients, followed by a bacterial count if pyuria is revealed. Experience has shown that routine urine microscopy by a precise method leads to the detection of many cases of occult urinary infection.Estimates of the incidence of pyelonephritis on the basis of necropsy evidence have ranged from 6 18 % (Brod, 1956) to 20% (Rhoads, Billings, and O'Conor, 1952). Many of these cases are undiagnosed, probably because obvious symptoms of urinary tract inflammation, such as dysuria and frequency of micturition, are often absent or slight, particularly if the infection is chronic.…”

mentioning

confidence: 99%

“…Estimates of the incidence of pyelonephritis on the basis of necropsy evidence have ranged from 6 18 % (Brod, 1956) to 20% (Rhoads, Billings, and O'Conor, 1952). Many of these cases are undiagnosed, probably because obvious symptoms of urinary tract inflammation, such as dysuria and frequency of micturition, are often absent or slight, particularly if the infection is chronic.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Simplified quantitative methods for bacteriuria and pyuria

McGeachie

Kennedy

1963

Journal of Clinical Pathology

View full text Add to dashboard Cite

SYNOPSIS Although pyelonephritis is a common disease, it escapes clinical detection in an undesirably high proportion of patients. The present unsatisfactory diagnostic position would be much improved by widespread screening of patients by simple yet reasonably accurate methods. Bacterial counts by the pour-plate technique and estimates of the white cell excretion per hour or day, while undoubtedly of diagnostic value, are probably unsuitable for use on a wide scale. In an attempt to find more convenient procedures a simplified stroke-plate method of bacterial counting and a simplified quantitative white cell count method were devised and applied to over 1,000 mid-stream urine samples from 398 patients. Good correlation was obtained between the simpler stroke-plate method of bacterial counting and the more time-consuming pour-plate method. The quantitative white cell procedure was a much more sensitive index of pyuria than wet-film microscopy, and comparison with the bacterial count results showed that it gave a useful indication of urinary infection. It is suggested that a quantitative bacterial count should replace non-quantitative culture methods when urinary infection is suspected and that the quantitative white cell count should be performed as a routine part of the initial clinical and laboratory assessment of all patients, followed by a bacterial count if pyuria is revealed. Experience has shown that routine urine microscopy by a precise method leads to the detection of many cases of occult urinary infection.Estimates of the incidence of pyelonephritis on the basis of necropsy evidence have ranged from 6 18 % (Brod, 1956) to 20% (Rhoads, Billings, and O'Conor, 1952). Many of these cases are undiagnosed, probably because obvious symptoms of urinary tract inflammation, such as dysuria and frequency of micturition, are often absent or slight, particularly if the infection is chronic. Thus, Kleeman, Hewitt, and Guze (1960) report that out of 629 cases of significant pyelonephritis seen at necropsy in a five-year period, only 104 (16.6%) were diagnosed clinically, although they stress that retrospective study of the case records indicated that there was suggestive information in 70% of all cases.

show abstract

Section: Results and Interpretationmentioning

confidence: 97%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Simplified quantitative methods for bacteriuria and pyuria

McGeachie

Kennedy

1963

Journal of Clinical Pathology

View full text Add to dashboard Cite

show abstract

“…They are divided into two groups : group 1 consists of 14 girls with normal urinary tracts or normal save for abnormalities considered secondary to infection2 (Fig 1, Patients 1-14) ; group 2 consists of six girls with intrinsic abnormalities of the urinary tract which may have predisposed them to infection (Fig 1, Patients [15][16][17][18][19][20].…”

Section: Methodsmentioning

confidence: 99%

Prevention of Recurrent Urinary Tract Infections in Girls

Holland¹,

West²

1963

Arch Pediatr Adolesc Med

View full text Add to dashboard Cite

Death from chronic pyelonephritis of several girls with otherwise normal urinary tracts has focused our attention on the importance of controlling bacterial infections of the kidney. At the same time, difficulties encountered in the management of kidney infections were emphasized by the stormy courses of six girls with frequently recurring pyelonephritis. Although these children had anatomically normal urinary tracts and each infection could be eradicated by appropriate therapy utilizing information gained from urine cultures and sensitivity studies, reinfection invariably followed. Prior to referral, several therapeutic approaches had been tried without achieving permanent remission, including one month of hospitalization for treatment with massive doses of antibiotic combinations. Finally, a program was instituted for the purpose of preventing recurrences.1 After the infections had been cleared by appropriate antibacterial drugs, the patient was started on methenamine mandelate and, when indicated, a urinary acidifying agent. This paper describes this prophylactic program and its effectiveness in preventing recurrences of pyelonephritis as determined by its use in 20 girls over the past five years.

show abstract

“…In recent years increasing attention has been paid to the behaviour of the renal tubule in pyelonephritis (Brod, 1956;Kleeman, Hewitt, and Guze, 1960;Kaitz, 1961), but there has been little systematic examination of the renal handling of hydrogen ion in this condition. Several authors have noted a failure to conserve bicarbonate in cases of pyelonephritis, but they have tended to distinguish between this disorder and renal tubular acidosis as the term is generally used (Schwartz and Relman, 1957;Lathem, 1958).…”

mentioning

confidence: 99%

Renal tubular acidosis of pyelonephritis with renal stone disease.

Cochran¹,

Smith²,

Nordin³

1968

BMJ

View full text Add to dashboard Cite

These findings seem to confirm that prognosis is improved by early diagnosis, which can be improved if routine examinations are carried out at intervals not exceeding six months.Probably a mass x-ray uni; concentrating on men aged 55 and over smoking 15 cigarettes a day could salvage four-year survivors at a cost of only £300 each. Every 1,000 films taken would pick up a potential four-year survivor.This study was possible only with the help of many people. We are grateful to them all, particularly the staffs of the Registrar

show abstract

Chronic Pyelonephritis

Cited by 83 publications

References 5 publications

Simplified quantitative methods for bacteriuria and pyuria

Simplified quantitative methods for bacteriuria and pyuria

Prevention of Recurrent Urinary Tract Infections in Girls

Renal tubular acidosis of pyelonephritis with renal stone disease.

Contact Info

Product

Resources

About