Chronic Rhinosinusitis and Olfactory Dysfunction

Raviv, Joseph; Kern, Robert C.

doi:10.1159/000093757

Cited by 27 publications

(30 citation statements)

References 43 publications

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“…However, this perception of 'taste' does not reflect the gustatory dysfunction but the olfactory contribution to the food appreciation via the retronasal route [5] . Loss of appetite, difficulties with cooking, decreased enjoyment of a good meal and its impact on many social activities have been reported [2,3,6] .…”

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confidence: 99%

Olfactory Dysfunction in Nasal Polyposis: Correlation with Computed Tomography Findings

Konstantinidis¹,

Triaridis²,

Printza³

et al. 2007

ORL

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Aims: This study evaluates if a computed tomography (CT) scan is useful to assess the olfactory loss in sinonasal disease, and if a preoperative CT scan has a predictive value for the long-term outcome regarding olfaction. Methods: Thirty-one patients with nasal polyposis were included. Olfactory function was assessed with the ‘Sniffin’ Sticks’ test and subjective perception recorded with a visual analogue scale. CT scans were assessed with the Lund-Mackay system and the Damm nasal segmentation. Patients were retested after endoscopic sinus surgery in a follow-up appointment at least 1 year later. Results: Disease in the upper meatus and the posterior portion of the middle meatus strongly affects olfactory function. Lund-Mackay scores were significantly correlated with preoperative olfactory test results. Preoperative subjective ratings had a significant correlation only with present disease in the anterior upper meatus. Postoperative results were significantly decreased. Their relative percentage change was correlated only with the preoperative presence of disease in the anterior upper meatus. No correlation was found between the Lund-Mackay score and the postoperative olfactory results. Conclusions: Olfactory dysfunction in nasal polyposis is strongly related to specific obstructed nasal areas. A CT scan has no predictive value for the long-term surgical outcome regarding olfaction.

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confidence: 99%

Olfactory Dysfunction in Nasal Polyposis: Correlation with Computed Tomography Findings

Konstantinidis¹,

Triaridis²,

Printza³

et al. 2007

ORL

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“…Olfaction also plays a key role in the hygiene matters, sensing danger, as well as sexual behavior. Among the various causes of olfactory disorders, nasal and sinus diseases are very important as they are the most treatable causes of olfactory loss [1,2].…”

Section: Introductionmentioning

confidence: 99%

“…Medical and surgical treatments of chronic sinusitis have different rates of success in improving the sense of smell in various pathologies [1]. Some reports claimed that only medical therapy using corticosteroids has effect on improving olfactory sensation [7], but other reports shows the effect of sinus surgery on it [8].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of FESS in Smell Improvement of Sinusitis Patients

Saedi

Sadeghi

Yazdani

et al. 2012

Indian J Otolaryngol Head Neck Surg

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The aim of this research was to verify the effect of functional endoscopic sinus surgery (FESS) on olfactory dysfunction in patients who suffer from chronic rhinosinusitis. We enrolled prospective consecutive patients at a tertiary institution who were undergoing FESS; for these patients prolonged medical therapy for chronic rhinosinusitis had failed. Patients were asked to grade their olfactory dysfunction from 1 to 5 with 1 representing lack of any smell function and 5 representing a completely normal sense of smell. Moreover, the pre-and postoperative smell identification test of the University of Pennsylvania was performed for all participating patients. In addition, data including computed tomography scores, nasal endoscopy, and the presence or absence of asthma as well as smoking habits were recorded and analyzed. Patients were followed at least 1 year after surgery. Data were collected on 89 patients who had undergone sinus surgery. Postoperative olfactory function was 77% improved for all subjects as a group. Higher involvement of sinus in computed tomography correlated with poorer results in olfactory UPSIT40 score. Patients' olfaction was significantly related to polyp pathology, duration of disease, age, smoking habits and history of asthma. A variety of patients' characteristics have impact on olfactory outcome of sinusitis patients after FESS.

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“…In the literature, CRS is described as the most common cause of olfactory dysfunction, accounting for 14-30% of cases (Holbrook and Leopold 2006;Mott and Leopold, 1991;Raviv and Kern 2004;Seiden and Duncan, 2001). Inversely, olfactory impairment is a common symptom affecting 61-83% of patients with CRS (Bhattacharyya, 2003;Litvak et al, 2008;Orlandi and Terrell, 2002;Soler et al, 2008).…”

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confidence: 99%

“…Nevertheless up to one quarter of patients with CRS are unaware of their decreased olfactory abilities, probably because the olfactory dysfunction in CRS develops slowly and in consequence only a few patients note this disorder (Nordin et al, 1995). Psychophysical tests results show that patients with CRS have quantitative disorders, between hyposmia and anosmia (Holbrook and Leopold 2006;Mott and Leopold, 1991;Raviv and Kern 2004;Seiden and Duncan, 2001;Welge-Luessen, 2009) and may report fluctuating symptoms (Apter et al, 1999). Also it is widely known that patients with CRS with polyps have a higher incidence of smell symptoms and anosmia than patients with CRS without polyps (Hellings and Rombaux, 2009).…”

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confidence: 99%