Chronic spontaneous urticaria

Hsieh, Jane; Lee, Jason K.

doi:10.1503/cmaj.150951

Cited by 1 publication

(1 citation statement)

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“…The prevalence of CSU has been reported to be about 0.5% to 1%, [ 5 – 7 ] with a peak incidence between the ages of 20 and 40 years. [ 8 ] Women are affected twice as often as men. [ 9 ] The etiology of CSU is difficult to determine, but it has been reported to be related to food, medicine, physical factors, vitamin D deficiency, [ 10 ] stress, [ 2 , 11 ] chronic occult infection, [ 12 ] and autoimmune diseases.…”

Section: Introductionmentioning

confidence: 99%

Multi-center study for acupuncture combined with Chinese medicine in the treatment of chronic spontaneous urticaria based on the theory of taking shu-stream points when the disease is aggravated

et al. 2020

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Chronic spontaneous urticaria (CSU) is a common dermatologic disease that seriously affects patient quality of life. The choice of therapy to control the disease and prevent its recurrence has always presented a difficult clinical issue. Previous studies have shown that traditional Chinese medicine is a safe and effective treatment for CSU. Recently, the temporal rhythms of CSU, a disease characterized by intermittent flares of active disease and periods of little or no disease, have attracted the attention of traditional Chinese medicine researchers. We designed a multicenter, randomized, controlled study to evaluate the efficacy and safety of combining a Chinese herbal formulation with acupuncture using shu-stream acupoints applied on the corresponding time meridians during disease exacerbations. We plan to recruit 111 outpatients with CSU aged 18 to 65 years. Participants will be randomized to 1 of the 3 groups: group A, which will be given basic acupuncture and the herbal formulation dangui yinzi; group B, which will be given danggui yinzi and shu-stream acupuncture; and a control group, which will be given danggui yinzi alone. Patients will be treated for 4 weeks and followed for 8 additional weeks. Investigators will evaluate the following parameters: the symptoms and side effects of treatment, quality of life (using the chronic urticaria quality of life questionnaire), and overall patient condition. Each week, patients will also complete the measurement of 7-day urticarial activity score. This is the first use of a combination of shu-stream acupoints and Chinese herbal medicine in the treatment of CSU. If successful, it will prove to be a simple, inexpensive, treatment strategy for solving a difficult clinical problem.

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