Chronic Upper Airway Cough Syndrome Secondary to Rhinosinus Diseases (Previously Referred to as Postnasal Drip Syndrome )

Pratter, Melvin R.

doi:10.1378/chest.129.1_suppl.63s

Cited by 236 publications

(192 citation statements)

References 44 publications

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“…More recently, the term ''upper airway cough syndrome'' has been favoured [73]. Despite sparse evidence from randomised controlled trials, nasal decongestants and first-generation antihistamines have been advocated as first-line therapy [74].…”

Section: Question 15mentioning

confidence: 99%

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

et al. 2014

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In 2011, a European Respiratory Society Task Force embarked on a process to determine the position and clinical relevance of the cough hypersensitivity syndrome, a disorder characterised by troublesome coughing often triggered by low levels of thermal, mechanical or chemical exposure, in the management of patients with chronic cough. A 21-component questionnaire was developed by an iterative process supported by a literature review. 44 key opinion leaders in respiratory medicine were selected and interviewed as to their opinions.There was a high degree of unanimity in the responses obtained, with all opinion leaders supporting the concept of cough hypersensitivity as a clinically useful paradigm. The classic stratification of cough into asthmatic, rhinitic and reflux-related phenotypes was supported. Significant disparity of opinion was seen in the response to two questions concerning the therapy of chronic cough. First, the role of acid suppression in reflux cough was questioned. Secondly, the opinion leaders were split as to whether a trial of oral steroids was indicated to establish a diagnosis of eosinophilic cough.The cough hypersensitivity syndrome was clearly endorsed by the opinion leaders as a valid and useful concept. They considered that support of patients with chronic cough was inadequate and the Task Force recommends that further work is urgently required in this neglected area. @ERSpublications Cough hypersensitivity syndrome was clearly endorsed by opinion leaders as a valid and useful concept

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Section: Question 15mentioning

confidence: 99%

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

et al. 2014

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“…The diagnosis of PND-induced cough is made by symptom history, physical examination, radiological findings and response to therapy. 10 There are numerous rhinological conditions that can give rise to a PND including allergic/non-allergic rhinitis, nasal polyps and rhinosinusitis. The latter is the main, however, is considered the most common pathology associated with PND.…”

Section: Post Nasal Dripmentioning

confidence: 99%

“…Recent clinical guidelines for the management of chronic cough by the American College of Chest Physicians recommend using the term upper airway cough syndrome (UACS), instead of 10 to reflect fact that this is often associated with upper airway abnormalities, such as extrathoracic airway hypersensitivity. 18 Recent studies on patients with allergic and nonallergic rhinitis showed increased neuronal receptors in their nasal mucosa compared to controls.…”

Section: Relationship Between Cough and Gord And Pndmentioning

confidence: 99%

Rhinosinusitis, laryngopharyngeal reflux and cough: An ENT viewpoint

Saleh

2009

Pulmonary Pharmacology & Therapeutics

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Chronic cough is a common presentation. Post nasal drip (PND) and gastro-oesophageal reflux are mostly implicated in the aetiology. Directly examining the larynx can often help to demonstrate laryngitis or inter-arytenoid oedema that is mostly attributed to reflux. Although "the syndrome of postnasal drip" is considered as a major cause for chronic cough, evidence of its existence is mostly difficult to elicit on examination. Furthermore, the majority of patients with "postnasal drip" seen in ENT outpatients do not complain of cough. Evidence does suggest there is a link between post nasal drip and cough. The fact that some patients present with cough in association with this syndrome and others do not is still not well understood.

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“…Differential diagnosis of the PNDS-induced cough includes bacterial sinusitis, post-infectious rhinitis, allergic rhinitis, drug-induced rhinitis, rhinitis gravidarum etc. In recent years it has been suggested to use the term "upper airway cough syndrome" (UACS) as cough may be caused not only be nasal and nasopharyngeal mucus drip, but also inflammation of the upper respiratory tract in the area of cough receptors [1]. Doctors' awareness of this syndrome is important, as cough in this situation is not always correctly interpreted and erroneously considered a symptom of chronic bronchitis.…”

mentioning

confidence: 99%