Chronic venous leg ulcers: Effects of foam sclerotherapy on healing and recurrence

Grover, Gagandeep Singh; Tănase, Andrei; Elstone, A.; Ashley, S.

doi:10.1177/0268355514557854

Cited by 27 publications

(16 citation statements)

References 19 publications

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“…According to Grover et al, in a sample of 50 limbs with a median follow-up time of 15.2 months, there was recurrence in 4/50 (8%) at 12 months. 19 The partial and total recanalization rates observed in the present study were 26% and 21%, respectively. In some aspects these results are similar to those reported by Howard et al, 18 who observed complete recanalization in 27% and partial recanalization in 58%.…”

Section: Discussionsupporting

confidence: 49%

Impacto da escleroterapia com espuma de polidocanol guiada por ultrassom em pacientes com úlcera venosa

Silva¹,

Araujo²,

Amaral³

et al. 2017

J. vasc. bras.

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Background: Ultrasound-guided polidocanol foam sclerotherapy is used to treat patients with venous ulcers. It is a minimally invasive procedure and is simple to perform, but it has high relapse rates. Objectives: To report short to medium term results in patients with venous ulcers treated using ultrasound-guided polidocanol foam sclerotherapy. Methods: A sample of 19 patients who had been treated with ultrasound-guided polidocanol foam sclerotherapy between January 2013 and December 2014 were followed-up. Time taken for ulcers to heal, improvement of clinical symptoms, recanalization of treated veins, and relapse of symptoms and of venous ulcers were analyzed. Results: Fifteen of the patients analyzed were female (78.9%) and four were male (21.1%). Overall mean age was 53 years. Follow-up times ranged from 448 days to 1,276 days (mean of 791 days). The mean duration of active ulcers was 53 months. At postoperative follow-up assessments, total recanalization was observed in 15.7%, partial recanalization in 21%, and occlusion in 47.3% of the veins that had been treated. There was only one case of ulcer relapse. Analysis of mean Venous Clinical Severity Scores (VCSS) revealed a significant difference from before to after the procedure, with a variation of 11.2 (p < 0.01). Conclusions: Ultrasound-guided foam sclerotherapy has high rates of therapeutic success and achieves high rates of venous ulcer healing.

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Section: Discussionsupporting

confidence: 49%

Impacto da escleroterapia com espuma de polidocanol guiada por ultrassom em pacientes com úlcera venosa

Silva¹,

Araujo²,

Amaral³

et al. 2017

J. vasc. bras.

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“…26 Abolition of venous reflux performed by UGFS also promotes ulcer healing. 27,28 Deep venous reflux is the main risk factor for delayed healing, according to the present multivariate analysis. Ulcer size and duration, claimed to be other main determinants of healing time, 29 are also important negative prognostic factors in the present case series, together with PAOD.…”

Section: Discussionmentioning

confidence: 52%

Recalcitrant Venous Leg Ulcers May Heal by Outpatient Treatment of Venous Disease Even in the Presence of Concomitant Arterial Occlusive Disease

Mosti¹,

Cavezzi

Massimetti

et al. 2016

European Journal of Vascular and Endovascular Surgery

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“…[ 9 – 13 ] Emerging evidence of several randomized controlled trials (RCTs) published in recent years suggests a benefit of SF in patients with VLUs. [ 14 – 16 ] A prospective randomized study from Kulkarni et al [ 17 ] shows that SF agents can significantly improve the healing rate of VLUs and reduce the recurrence rate of VLUs. Another study showed that correction of superficial venous reflux in the lower limbs can help the healing of venous ulcers in the lower limbs.…”

Section: Introductionmentioning

confidence: 99%

The safety and efficacy of Sclerosing foam on treating venous leg ulcers

Fan

Yang

et al. 2020

Medicine

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Background: Venous leg ulcers (VLUs) are common throughout the world, which seriously affects the patient's work and life. Relevant researches suggested that sclerosing foam (SF) has potential benefits for VLUs. However, there is no consistent conclusion. The purpose of our study is to assess whether SF is effective and safe for VLUs. Methods: Relevant clinical randomized controlled trials will be obtained from a search of 8 databases (with no language restrictions) from their inception to May 2020: PubMed, the Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure Database, Wanfang Database, China Science and Technology Journal Database, and Chinese Biological Medicine. Data will be analyzed using RevMan 5.3 after literature screening and data extraction according to predefined inclusion and exclusion criteria. Cochrane Collaboration Risk of bias Tool will be applied in evaluating the quality of enrolled articles. The primary outcome is Closure of venous leg ulcers, ulcer healing rate, adverse events related to SF. The secondary outcomes include ulcer healing time, ulcer recurrence rate, pain. Risk ratio will be used for categorical data; mean differences will be used for measurement data. Where possible and appropriate, meta-analysis will be performed for each outcome. Results: To clarify whether Sclerosing foam can be safe and efficient on treating venous leg ulcers. Conclusion: Our review will provide useful information to judge whether Sclerosing Foam is an effective and safe intervention for patients with venous leg ulcers.

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Chronic venous leg ulcers: Effects of foam sclerotherapy on healing and recurrence

Abstract: This study affirms the role of ultrasound-guided foam sclerotherapy as a safe and effective option for abolition of superficial reflux.

Cited by 27 publications

References 19 publications

Impacto da escleroterapia com espuma de polidocanol guiada por ultrassom em pacientes com úlcera venosa

Impacto da escleroterapia com espuma de polidocanol guiada por ultrassom em pacientes com úlcera venosa

Recalcitrant Venous Leg Ulcers May Heal by Outpatient Treatment of Venous Disease Even in the Presence of Concomitant Arterial Occlusive Disease

The safety and efficacy of Sclerosing foam on treating venous leg ulcers

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