Chronic wounds – Recommendations for diagnostics and therapy

Erfurt‐Berge, Cornelia; Renner, Regina

doi:10.1016/j.rvm.2015.05.001

Cited by 7 publications

(7 citation statements)

References 38 publications

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“…Wound healing has always been an area of concern for medical community, but the nowadays interest for this topic is significantly amplified, because of the increased mortality rate associated with chronic wounds. Several factors are important in the effective treatment of wounds, including the debridement stage that consists in removing the non-viable or infected tissue from wound environment [17]. In chronic wounds, it is recommended to perform the debridement process as early as possible, by using either non-selective (surgical and mechanical debridement) or selective (autolytic, enzymatic and biodebridement) methods.…”

Section: Wound Care and Dressingsmentioning

confidence: 99%

The importance of oxygen release in diabetic foot ulcer wounds

2019

Bioengineering Int

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Oxygen is the essential element required for proper physiological function of cells, tissues and organs within healthy human body. Thanks to its intricate structure, the skin provides a multiprotective barrier against traumatic and non-traumatic injuries, but also a complex and successful self-healing process of the affected tissue. In the particular case of chronic skin wounds, such as diabetic foot ulcer wounds, there is an immediate demand to develop alternative procedures that prevent infection, speed up healing and eliminate any disrupting factor that may interfere with the therapeutic process. Given the importance of oxygen during wound healing cascade, impressive attention was oriented towards the fabrication of oxygen-releasing wound dressings.

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Section: Wound Care and Dressingsmentioning

confidence: 99%

The importance of oxygen release in diabetic foot ulcer wounds

2019

Bioengineering Int

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“…These type of wounds are often caused by vascular, haemostaseological or metabolic disorders, as well as inflammatory skin diseases, cancer or infections. (Erfurt-Berge and Renner, 2015) Hospitalization is often required with consequent high costs for the healthcare system. For example, approximately 2 percent of health budgets are used for chronic wound therapies and care.…”

Section: Chronic Woundsmentioning

confidence: 99%

Hydrogels in Wound Management

Caló¹,

Ballamy²,

Khutoryanskiy³

2018

Hydrogels

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“…Aging is frequently associated with multimorbidity, and along with multiple diseases the occurrence of non-healing ulcers is relevant [ 1 ]. Most non-healing wounds are associated with some of the most common conditions among older patients, such as vascular disease, venous insufficiency, disability, unrelieved pressure, and diabetes [ 1 – 3 ]. Patients suffering from non-healing wounds are mostly in the aging population presenting with multimorbidity [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…Most non-healing wounds are associated with some of the most common conditions among older patients, such as vascular disease, venous insufficiency, disability, unrelieved pressure, and diabetes [ 1 – 3 ]. Patients suffering from non-healing wounds are mostly in the aging population presenting with multimorbidity [ 3 ]. Tissue repair capacity worsens with age and wound healing has been described as being reduced in older patients (> 70 years) in comparison with younger ones [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Assessment of frailty in elderly patients attending a multidisciplinary wound care centre: a cohort study

et al. 2021

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Background The incidence of frailty and non-healing wounds increases with patients’ age. Knowledge of the relationship between frailty and wound healing progress is greatly lacking. Methods The aim of this study is to characterize the degree of frailty in elderly patients attending a multidisciplinary wound care centres (MWCC). Additionally, we seek to assess the impact of frailty on the wound healing rate and wound healing time. An open cohort study was conducted on 51 consecutive patients aged > 70 years treated for wounds at an MWCC of an intermediate care hospital. The frailty score was determined according to the Frail-VIG index. Data were collected through patient questionnaires at the beginning of the study, and at 6 months or upon wound healing. Wounds were followed up every 2 weeks. To analyse the relationship between two variables was used the Chi-square test and Student’s or the ANOVA model. The t-test for paired data was used to analyse the evolution of the frailty index during follow-up. Results A total of 51 consecutive patients were included (aged 81.1 ± 6.1 years). Frailty prevalence was 74.5% according to the Frail-VIG index (47.1% mildly frail, 19.6% moderately frail, and 7.8% severely frail). Wounds healed in 69.6% of cases at 6 months. The frailty index (FI) was higher in patients with non-healing wounds in comparison with patients with healing wounds (IF 0.31 ± 0.15 vs IF 0.24 ± 0.11, p = 0.043). A strong correlation between FI and wound healing results was observed in patients with non-venous ulcers (FI 0.37 ± 0.13 vs FI 0.27 ± 0.10, p = 0.015). However, no correlation was observed in patients with venous ulcers (FI 0.17 ± 0.09 vs FI 0.19 ± 0.09, p = 0.637). Wound healing rate is statically significantly higher in non-frail patients (8.9% wound reduction/day, P25-P75 3.34–18.3%/day;AQ6 p = 0.044) in comparison with frail patients (3.26% wound reduction/day, P25-P75 0.8–8.8%/day). Conclusion Frailty is prevalent in elderly patients treated at an MWCC. Frailty degree is correlated with wound healing results and wound healing time.

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Chronic wounds – Recommendations for diagnostics and therapy

Cited by 7 publications

References 38 publications

The importance of oxygen release in diabetic foot ulcer wounds

The importance of oxygen release in diabetic foot ulcer wounds

Hydrogels in Wound Management

Assessment of frailty in elderly patients attending a multidisciplinary wound care centre: a cohort study

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