Archaeological interpretations of ancient economies have been strengthened by chemical analyses of ceramics, which provide the clearest evidence for economic activity, and comprise both the objects of exchange and its means. Pottery is often manufactured from local materials, but its compositional diversity typically prevents significant patterns of resource utilization from being identified. Centrally located and positioned on traditional shipping routes, Cyprus maintained ties with and supplied a variety of distinctive ceramic products to the major commercial centres in the eastern Mediterranean throughout Antiquity. We analysed two Cypriot fine wares and a variety of utilitarian pottery, as well as samples of extant Cypriot clays to determine source provenance. These chemical analyses provide an objective indication of the origins of ancient (Bronze Age and Roman) ceramics manufactured on Cyprus. The distribution of the probable clay sources and the links between pottery style and the material environment also afford a perspective on the spatial organization of large-scale pottery production on the island. Compositional analysis provides the means to assemble geographies of pottery production and to unravel the interregional system of exchange that operated in Antiquity, but the ability to accomplish these tasks is predicated on systematic analyses of ceramic products and raw materials that are found far beyond the bounds of individual archaeological sites.