Chronisch rezidivierende multifokale Osteomyelitis

Schultz, Christian; Jonas, S.; Schnekenburger, F. G.; Russlies, Martin; Kruse, K.; Bucsky, Peter

doi:10.1007/s001120050218

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…Schulz et al . reported their own experiences in treating a total of 5 patients between 7–17 years old [ 5 ]. These patients had initial complaints involving the ankles, the thoracic vertebrae, a rib and the clavicle.…”

Section: Case Presentationmentioning

confidence: 99%

Chronic recurrent multifocal osteomyelitis manifested as painful clavicular swelling: a case report

Bleckwenn

Sommer²,

Weckbecker

2014

BMC Res Notes

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BackgroundChronic recurrent multifocal osteomyelitis is a form of non-bacterial osteomyelitis which occurs primarily in childhood. In some cases painful bone swelling occurs. After a malignancy has been ruled out, antibiotic therapy is often started to treat the osteomyelitis. The course of this benign disease is self-limiting and is not positively affected by the antibiotic therapy.Case presentationA 14-year-old German girl from South Africa came to the surgery with painful swelling in the right clavicle. The condition had first appeared two months earlier. The patient was unable to identify a trigger. In addition, the patient exhibited painless swelling in the area of the 5th metatarsal of the left foot. Chronic recurrent multifocal osteomyelitis was diagnosed based on characteristic clinical symptoms and imaging. Treatment with ibuprofen had caused the symptoms to regress rapidly.ConclusionThe case demonstrates to general practitioners and other clinicians that a prolonged administration of antibiotics can be prevented by means of a comprehensive diagnostic procedure for possible bacterial osteomyelitis.

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Section: Case Presentationmentioning

confidence: 99%

Chronic recurrent multifocal osteomyelitis manifested as painful clavicular swelling: a case report

Bleckwenn

Sommer²,

Weckbecker

2014

BMC Res Notes

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“…Sie fanden bei 4 Kindern (davon 3 Mädchen) zwischen 5 und 11 Jahren eine als ¹chronisch oder subakutª bezeichnete, nicht-eitrige und symmetrische Osteomyelitis, histopathologisch ± bereits wegweisend ± unter dem Bild der plasmazellulären Osteomyelitis, im Röntgenbild asteolytisch bis hyperostototisch und bezüglich des Befallmusters ¹cleido-metaphysärª (Probst 1976 So ist also die CRMO vor wenigen Jahren umfassend beschrieben [61,62,66] und durch die Definition ihrer Erscheinungsform im Erwachsenenalter (adulte CRMO) ergänzt worden [56]. Sie wird jetzt auch im deutschsprachigen Raum häufiger gefunden, in der Pädiatrie [20,21,23,27,65,67,73], in der Rheumatologie [51,52,57,61] und in der Radiologie [13,43,62]. Noch nicht ausreichend informativ ist die orthopädische und die pathologisch-anatomische Literatur über die CRMO, deren Einzeldarstellungen in ihrer Deutung international noch auseinanderdriften [1, 10,12,20,22,25,39,68,71,72,74,79].…”

Section: Rückblickunclassified

Die chronische rekurrierende multifokale Osteomyelitis

Schilling

Eckardt²,

Kessler³

2000

Z Orthop Ihre Grenzgeb

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The aim of this paper is to give a detailed description of the so-called "chronic recurrent multifocal osteomyelitis" (CRMO). The clinical, radiological and histopathological results of an analysis of 29 cases (15 children/adolescents and 14 adults) are presented and correlated to current data from the literature. We could delinate the following points: 1. CRMO is a systemic aseptic inflammation of the bone marrow (Osteitis), it can occur polytopically and association with pustulous dermatologic symptoms is possible. 2. It is not a rare disease 3. Osteomyelitis is probably "reactive" and a plasma-cell sclerotic process with ist own characteristic histologic three-phase course. 4. We could observe 5 specific types of localization which can be documented by X-ray or bone scan. 5. Accompanying arthritis os often present, especially "sympathetic coxitis". 6. The use of drugs in treatment of CRMO (i.e. azithromycin, calcitonin, and bisphosphonates) is discussed. In conclusion we want to point out, that 1. 99mTC bone scan should always be performed when there is suspicion for CRMO to reveal the pattern of affection, 2. the rheumatologist and dermatologist should be contacted, 3. operation is normally not necessary for treatment of the mostly self-limitin disease, and 4. the term "SAPHO syndrome" should be avoided, further differentiation of the diagnosis is necessary.

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