Chryseobacterium gleum infection in patient with extreme malnutrition and hepatic lesion – case report

Abstract

Chrysobacterium gleum is a nonmotile, oxidase positive, non-fermentative unsporulate Gram-negative bacillus, bacteria belonging to the genus Chrysobacterium. Infections caused by Chrysobacterium spp are usually health care associated and the most frequent in immunocompromised patients and neonates. In this report we present a case of a 35-yearold female patient admitted to the hospital for extreme malnutrition and a hepatic lesion. Chrysobacterium gleum was isolated from tracheal aspirate and blood culture. The strain was identified with Microflex MALDI Biotyper (Bruker Daltonik, Fremont, CA). The patient was successfully treated with piperacillin/tazobactam. Empirical therapy is difficult due to intrinsic resistance to most antimicrobials which are usually effective against Gram-negative bacteria.

Emerging Bacterial Pathogens in the COVID-19 Era: Chryseobacterium gleum—A Case in Point

“…A long hospital stay and empirical broad-spectrum antibiotics make the patients prone to acquire nosocomial infections especially with unconventional organisms and C. gleum is one such rare nosocomial pathogen. [8][9][10][11] This study highlights the role of C. gleum in patients who recovered from COVID-19-induced pneumonia and later presented with bacterial pneumonia. To the best of our knowledge, this is the first case series-based study showing ventilator-associated pneumonia (VAP) due to C. gleum in patients recovered post-COVID-19 pneumonia.…”

Chryseobacterium gleum in a man with prostatectomy in Senegal: a case report and review of the literature

“…In Croatia, Dijana et al . published in 2015 a case of C. gleum infection in a patient with malnutrition and hepatic lesion [5]. The patient with respiratory insufficiency had developed septic shock, which necessitated intubation and mechanical ventilation.…”

“…(2015) [18]IndiaM/48UrineCuredPyonephrosisTetracyclineDijana et al . (2015) [5]CroatiaF/35Blood/Tracheal aspirateCuredHepatic lesion/malnutritionPiperacillin/TazobactamRamya et al . (2015) [4]IndiaM/62UrineCuredRenal calculi/HydronephrosisPiperacillin/TazobactamBaha et al .…”

Sepsis Due to <i>Chryseobacterium gleum</i> in a Diabetic Patient with Chronic Obstructive Pulmonary Disease: a Case Report and Mini Review

“…Very limited clinical data are available for this newly identified pathogen, and it has been rarely reported as a cause of sepsis anywhere in the world (Table 1) (8). The correct identification of this pathogen is essential due to its contrasting susceptibility pattern to other NFGNBs.…”

“…To the best of our knowledge, the present case is the second reported case of sepsis due to C. gleum in the world. In 2015, Brkic et al reported a case of a 35-year-old female patient with extreme malnutrition and a hepatic lesion, whose blood and tracheal aspirate cultures showed growth of C. gleum (8).…”