Circadian rhythmicity and photic plasticity of myosin gene transcription in fast skeletal muscle of Atlantic cod (Gadus morhua)

Lazado, Carlo C.; Nagasawa, Kazue; Babiak, Igor; Kumaratunga, Hiruni; Fernandes, Jorge M.O.

doi:10.1016/j.margen.2014.04.011

Cited by 17 publications

(14 citation statements)

References 40 publications

(44 reference statements)

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“…We have not investigated if the muscle cells express photopigments such as melanopsins in culture but we have previously reported that cryptochromes, a group of genes coding for photosensitive proteins, are expressed in Atlantic cod skeletal muscle [16]. Further, we cannot conclusively exclude light as a synchronization factor in Atlantic cod skeletal muscle, since the present study and previous reports suggest that this tissue is responsive to changes in lighting regimes [15,16,17,19].…”

Section: Discussioncontrasting

confidence: 59%

“…The rhythmic expression of several clock genes in fast skeletal muscle of Atlantic cod suggests the presence of a peripheral clock in this tissue [15,16]. In the present study, we developed in vitro (myosatellite cell culture) and ex vivo (muscle explant) models of muscle growth to ascertain its autonomy.…”

Section: Discussionmentioning

confidence: 98%

“…There is evidence that fishes have a functional clock system in fast skeletal muscle, based on the identification of several conserved molecular components of the core clock machinery and their rhythmicity during a daily/circadian cycle [5,15,16]. In some teleost species, muscle growth displays photic plasticity [15,17], thus making them a particularly interesting model to study the muscle peripheral clock system and its entrainment by light.…”

Section: Introductionmentioning

confidence: 99%

“…In some teleost species, muscle growth displays photic plasticity [15,17], thus making them a particularly interesting model to study the muscle peripheral clock system and its entrainment by light. It is known that photoperiod is an important environmental factor in driving a number of physiological processes in Atlantic cod (Gadus morhua), namely somatic growth and sexual maturation [17][18][19].…”

Section: Introductionmentioning

confidence: 99%

“…It is known that photoperiod is an important environmental factor in driving a number of physiological processes in Atlantic cod (Gadus morhua), namely somatic growth and sexual maturation [17][18][19]. In particular, Atlantic cod juveniles reared under continuous illumination were 13% heavier than those kept under natural photoperiod conditions for 120 days, and this effect was associated with changes in expression of muscle-and DNA methylation-related genes [15,17,20].…”

Section: Introductionmentioning

confidence: 99%

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In vitro and ex vivo models indicate that the molecular clock in fast skeletal muscle of Atlantic cod is not autonomous

et al. 2014

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Section: Discussioncontrasting

confidence: 59%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In vitro and ex vivo models indicate that the molecular clock in fast skeletal muscle of Atlantic cod is not autonomous

et al. 2014

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Myosin XVIII

Taft

Latham

2020

Advances in Experimental Medicine and Biology

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The Influence of Short-term Fasting on Muscle Growth and Fiber Hypotrophy Regulated by the Rhythmic Expression of Clock Genes and Myogenic Factors in Nile Tilapia

Chu

Liu

et al. 2018

Mar Biotechnol

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Circadian clock genes and myogenic factors are tightly integrated to influence muscle growth upon dietary deprivation in animals. In this study, we reported that upon short-term fasting of Nile tilapia juveniles for 7 and 15 days, the growth of the fish stagnated and the size of muscle fibers decreased. To reveal the molecular mechanisms of how starvation affects fish muscle growth, we analyzed the rhythmic expression of circadian clock genes and myogenic factors. After 7 and 15 days of fasting treatment, the muscle tissues were collected for 24 h (at zeitgeber times ZT0, ZT3, ZT6, ZT9, ZT12, ZT18, ZT21, and ZT24) from tilapia juveniles. Among the 27 clock genes, the expression of cyr1b, nr1d1, per1, clocka, clockb, ciarta, and aanat2 displayed a daily rhythmicity in normal daily cycle, while arntl2, cry1a, cry1b, npas2, nr1d2b, per2, per3, rorαb, clocka, clockb, nfil3, cipca, and cipcb exhibited daily rhythmicity in the fasting fish muscles. The transcript levels of clockb showed moderate positive correlation with the aanat2, ciarta, cry1b, and nr1d1 in the muscle tissue of normally fed Nile tilapia juvenile. In comparison of the two treatment modes, the expression levels of clocka, clockb, and cry1b showed the rhythmicity, but clockb expression was significantly decreased and the acrophase had shifted. The transcript levels of fbxo32 and pdk4 had either moderate or strong positive correlations with other daily expression of clock genes except arntl2 in the muscle after 7-day fasting. The expressions of myogenic regulatory factors were also either upregulated or downregulated. These observations demonstrated that dietary starvation might affect fish muscle growth by modulating the differential expression of circadian clock genes and myogenic factors. Thus, our work provides a better understanding of the molecular mechanism of dietary starvation on fish growth and may provide dietary administration in aquiculture.

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Circadian rhythmicity and photic plasticity of myosin gene transcription in fast skeletal muscle of Atlantic cod (Gadus morhua)

Abstract: Circadian rhythmicity and photic plasticity of myosin gene transcription in fast skeletal muscle of Atlantic cod (Gadus morhua

Cited by 17 publications

References 40 publications

In vitro and ex vivo models indicate that the molecular clock in fast skeletal muscle of Atlantic cod is not autonomous

In vitro and ex vivo models indicate that the molecular clock in fast skeletal muscle of Atlantic cod is not autonomous

Myosin XVIII

The Influence of Short-term Fasting on Muscle Growth and Fiber Hypotrophy Regulated by the Rhythmic Expression of Clock Genes and Myogenic Factors in Nile Tilapia

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