2003
DOI: 10.1152/ajpcell.00084.2002
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Circadian rhythms in surface molecules of rat blood lymphocytes

Abstract: Pelegrí, Carme, Jordi Vilaplana, Cristina Castellote, Manel Rabanal, À ngels Franch, and Margarida Castell. Circadian rhythms in surface molecules of rat blood lymphocytes.

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Cited by 44 publications
(27 citation statements)
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“…Exactly why we failed to replicate their Hct QTL is unknown at this time. One factor may have been time of day of collection, as Hct is known to show a circadian rhythm in rabbits and rats and (24,54) and probably in mice as well. In our work, we routinely kill and harvest between the hours of 0900 and 1200, i.e., 3-6 h after lights are turned on in the vivarium.…”
Section: Discussionmentioning
confidence: 99%
“…Exactly why we failed to replicate their Hct QTL is unknown at this time. One factor may have been time of day of collection, as Hct is known to show a circadian rhythm in rabbits and rats and (24,54) and probably in mice as well. In our work, we routinely kill and harvest between the hours of 0900 and 1200, i.e., 3-6 h after lights are turned on in the vivarium.…”
Section: Discussionmentioning
confidence: 99%
“…Circadian rhythmicity is revealed in most immune functions, including circulating cells, lymphocyte metabolism and transformability, circulating hormones and other substances that may exert various actions on different targets of the immune system, cytokines, receptors, and adhesion molecules, cell cycle events in health and cancer, reactions to antigen challenge, and disease etiology and symptoms [24][25][26] . Circadian changes in the circulation of T, B, or natural killer lymphocyte subsets in peripheral blood and in the density of epitope molecules at their surface, which may be related to cell reactivity to antigen exposure, have been reported [27] .…”
Section: Discussionmentioning
confidence: 99%
“…Virtually all immunological variables investigated to date in animals and humans have been shown to display biological periodicity. In most of its components, the immune system shows regularly recurring, rhythmic variations in numerous frequencies, the circadian being the best known [43][44][45]. The results of our own studies on the circadian rhythmicity of immune parameters in rats receiving FCA or its vehicle are summarized in table 1.…”
Section: The Immune System Shows a Circadian Organizationmentioning
confidence: 99%