Circalunar clocks—Old experiments for a new era

Kaiser, Tobias S; Neumann, Jule

doi:10.1002/bies.202100074

Cited by 25 publications

(25 citation statements)

References 98 publications

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“…an endogenous time-keeping mechanism which synchronizes development and maturation with lunar phase. Circalunar clocks are common in marine organisms, but their molecular basis is still unknown 17 . Additionally, a circadian clock ensures that C. marinus adults only emerge during the low tide 18 .…”

Section: Introductionmentioning

confidence: 99%

An oligogenic architecture underlying ecological and reproductive divergence in sympatric populations

Brisevac

Peralta

Kaiser

2022

Preprint

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The evolutionary trajectories and genetic architectures underlying ecological divergence with gene flow are poorly understood. Sympatric timing types of the intertidal insect Clunio marinus (Diptera) from Roscoff (France) differ in lunar reproductive timing. One type reproduces at full moon, the other at new moon, controlled by a circalunar clock of yet unknown molecular nature. Lunar reproductive timing is a magic trait for a sympatric speciation process, as it is both ecologically relevant and entails assortative mating. Here we show that the difference in reproductive timing is controlled by at least four quantitative trait loci (QTL) on three different chromosomes. They are partly associated with complex inversions, but differentiation of the inversion haplotypes cannot explain the different phenotypes. The most differentiated locus in the entire genome, with QTL support, is the period locus, implying that this gene could not only be involved in circadian timing but also in lunar timing. Our data indicate that magic traits can be based on an oligogenic architecture and can be maintained by selection on several unlinked loci.

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Section: Introductionmentioning

confidence: 99%

An oligogenic architecture underlying ecological and reproductive divergence in sympatric populations

Brisevac

Peralta

Kaiser

2022

Preprint

Self Cite

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“…However, there are two reasons why the Moon phase should not affect the processes of the human body. In particular, gravitational forces do not depend on the phases of the Moon, but on the distance between the Earth and the Moon , and the alignment of the Sun, the Earth and the Moon [9]. Secondly, the lunar gravity is an extremely weak force.…”

Section: Discussionmentioning

confidence: 99%

Impact of Cosmobiological Factors on Chromosomal Anomalies Rates - Ethical Consideration

Serapinas

Narbekovas²

2022

JAMMR

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Backround: In recent years, there is an increasing number of data supporting the relation between lunar cycle and alterations in human body. For instance, it has been proved that hospitalized spontaneous abortions are significantly associated with the lunar cycle . Given that the most common cause of spontaneous abortion is chromosomal abnormalities of the embryo, we presumed that the lunar cycle could influence the occurrence of chromosomal diseases. From the point of bioethics it is a question if it is applicable to talk with patients about possible impact of cosmobiological factors on their case of chromosomal anomaly. Patients and Methods: We have selected 52 patients, who were bearing a fetus with a prenatally diagnosed chromosomal disorder, which included Down, Turner, Klinefelter, Patau and Edward syndromes. The control group (n=92) consisted of families, that were prenatally tested for chromosomal abnormalities and the results were negative. Then we gathered and analyzed information from patients' medical histories about various factors, which could have predisposed chromosomal disorders: age of both progenitors, consumption of medications during pregnancy, number of miscarriages, number of abortions, cases of genetic disorders in relatives, lunar phase on the day of conception. Results: Lunar phases at the time of conception in the test group distributed as following: new Moon 32.7 percent, first quarter 25.0 percent, full Moon 28.8 percent, third quarter 13.5 percent. In the control group lunar phases distributed as following: new Moon 29.3 percent, first quarter 27.2 percent, full Moon 26.1 percent, third quarter 17.4 percent. There was observed no statistically significant difference between test and control groups (p>0.05). OR for conception with chromosomal anomalies were increased in July (2.7(CI 95% 1.5-4.9) and December (3.2 (CI 95% 1.5-5.2) (p<0.05). OR showed decreased risk for chromosomal anomalies during conception at January (0.3 (CI 95% 0.1-0.7) , April (0.5 (CI 95% 0.2-0.7) and June 0.5 (CI 95% 0.2-0.8) (p<0.05). Conclusions: Our study showed there were no associations between lunar phase at the time of conception with the rates of chromosomal mutations. Conception in July and December increases the risk of chromosomal anomalies during conception. In contrast conception in January, April and June decreases chromosomal anomalies rates.

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“…Separate circadian and circatidal clockwork, as proposed by Naylor, also provide an explanation for seemingly endogenous semilunar rhythms, given their natural harmonic relationship; the Beat Hypothesis (Bünning and Müller, 1961) states that independent circadian and circatidal clocks would come into phase every ~14.8 days thereby generating a circasemilunar rhythm of behaviour coincident with the spring/neap tidal cycle (Neumann, 2014;Kaiser and Neumann, 2021). Tidalrelated rhythms may also emerge where sensitivity to an exogenous stimulus is regulated by the circadian clock, explained by the Coincidence Detection Hypothesis (Kaiser and Neumann, 2021). Tidal turbulence is strongest during the rising high tide, which occurs at the same time of day every ~14.8 days.…”

Section: How Are Circatidal Clocks Entrained?mentioning

confidence: 99%

“…Tidal turbulence is strongest during the rising high tide, which occurs at the same time of day every ~14.8 days. Therefore, if the circadian clock was to regulate the sensitivity of turbulence receptors to engage at a consistent time of day, the turbulence of the rising tide would be detected once every ~14.8 days and produce a circasemilunar stimulus (Kaiser and Neumann, 2021).…”

Section: How Are Circatidal Clocks Entrained?mentioning

confidence: 99%

Towards an Understanding of Circatidal Clocks

2022

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Circadian clocks are an intrinsic element of life that orchestrate appropriately timed daily physiological and behavioural rhythms entrained to the solar cycle, thereby conferring increased fitness. However, it is thought that the first archaic ‘proto-clocks’ evolved in ancient cyanobacteria in a marine environment, where the dominant time cues (zeitgebers) probably would have been lunar-driven and included tidal cycles. To date, non-circadian ‘marine clocks’ have been described with circatidal (~12.4 h), circasemilunar (~14.8 days), and circalunar (~29.5 days) periodicity, mostly studied in accessible but temporally complex intertidal habitats. In contrast to the well-described circadian clock, their molecular machinery is poorly understood, and fundamental mechanisms remain unclear. We propose that a multi-species approach is the most apposite strategy to resolve the divergence that arose from non-circadian clockwork forged in an evolutionary environment with multiple zeitgebers. We review circatidal clock models with a focus on intertidal organisms, for which robust behavioural, physiological, or genetic underpinnings have been explicated, and discuss their relative experimental merits. Developing a comprehensive mechanistic understanding of circatidal clocks should be a priority because it will ultimately contribute to a more holistic understanding of the origins and evolution of chronobiology itself.

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Circalunar clocks—Old experiments for a new era

Cited by 25 publications

References 98 publications

An oligogenic architecture underlying ecological and reproductive divergence in sympatric populations

An oligogenic architecture underlying ecological and reproductive divergence in sympatric populations

Impact of Cosmobiological Factors on Chromosomal Anomalies Rates - Ethical Consideration

Towards an Understanding of Circatidal Clocks

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