2023
DOI: 10.3390/ijms24032103
|View full text |Cite
|
Sign up to set email alerts
|

CircAMOTL1 RNA and AMOTL1 Protein: Complex Functions of AMOTL1 Gene Products

Abstract: The complexity of the cellular proteome facilitates the control of a wide range of cellular processes. Non-coding RNAs, including microRNAs and long non-coding RNAs, greatly contribute to the repertoire of tools used by cells to orchestrate various functions. Circular RNAs (circRNAs) constitute a specific class of non-coding RNAs that have recently emerged as a widely generated class of molecules produced from many eukaryotic genes that play essential roles in regulating cellular processes in health and diseas… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2

Citation Types

0
2
0

Year Published

2023
2023
2025
2025

Publication Types

Select...
2
1

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
(2 citation statements)
references
References 112 publications
0
2
0
Order By: Relevance
“…AMOTL1 is a component of tight junctions, interacting with actin to regulate cellular polarity and adhesion 37,38 . Recent studies have established a strong link between AMOTL1 and Hippo signaling pathway 39,40 . Specifically, AMOTL1 promotes the tumorigenesis via interacting with YAP1, a key factor of Hippo pathway, to induce its nuclear accumulation in gastric cancer and glioma 27,32 .…”
Section: Discussionmentioning
confidence: 99%
“…AMOTL1 is a component of tight junctions, interacting with actin to regulate cellular polarity and adhesion 37,38 . Recent studies have established a strong link between AMOTL1 and Hippo signaling pathway 39,40 . Specifically, AMOTL1 promotes the tumorigenesis via interacting with YAP1, a key factor of Hippo pathway, to induce its nuclear accumulation in gastric cancer and glioma 27,32 .…”
Section: Discussionmentioning
confidence: 99%
“…AMOTL1 is a component of tight junctions, interacting with actin to regulate cellular polarity and adhesion [ 38 , 39 ]. Recent studies have established a strong link between AMOTL1 and Hippo signaling pathway [ 40 , 41 ]. Specifically, AMOTL1 promotes tumorigenesis via interacting with YAP1, a vital factor of the Hippo pathway, to induce its nuclear accumulation in gastric cancer and glioma [ 27 , 32 ].…”
Section: Discussionmentioning
confidence: 99%