2023
DOI: 10.1007/s10528-023-10332-w
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CircRNA Circ_0000118 Regulates Malignancy of Cervical Cancer Cells by Regulating miR-211-5p/miR-377-3p/AKT2 Axis

Abstract: CircRNAs are implicated in the development of several cancers. Nevertheless, the involvement of circ_0000118 in the development of cervical cancer (CC) remains unclear. Circ_0000118 levels in tumor tissues and cells were examined by qRT-PCR. The function of circ_0000118 in regulating the malignancy of CC cells was investigated using functional assays, including CCK-8, colony formation, transwell, and tube formation experiments. The functional interaction between circ_0000118 and microRNAs were validated by dua… Show more

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Cited by 2 publications
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“…CircRNA-00284 arrests the cell cycle at the G0/G1 phase, increasing CC invasion through miRNA-506 sponging and Snail-2 upregulation (Ma et al, 2018). Hsa-circRNA-0000118 is implicated in cervical cancer malignancy by targeting miR-211-5p and miR-377-3p, preserving AKT2 levels (Wu et al, 2023) (Table 2).…”
Section: Circular Rna and Modulation Micrornas In Cervical Cancermentioning
confidence: 99%
“…CircRNA-00284 arrests the cell cycle at the G0/G1 phase, increasing CC invasion through miRNA-506 sponging and Snail-2 upregulation (Ma et al, 2018). Hsa-circRNA-0000118 is implicated in cervical cancer malignancy by targeting miR-211-5p and miR-377-3p, preserving AKT2 levels (Wu et al, 2023) (Table 2).…”
Section: Circular Rna and Modulation Micrornas In Cervical Cancermentioning
confidence: 99%